| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMS39129.1 | AMS39506.1 | AA2016_0187 | AA2016_0567 | Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cystathionine beta-lyase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. | 0.969 |
| AMS39129.1 | AMS41572.1 | AA2016_0187 | AA2016_2647 | Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | metFprotein; Pfam:pfam02219 Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.989 |
| AMS39129.1 | AMS41708.1 | AA2016_0187 | AA2016_2783 | Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Pfam:pfam02219 Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.991 |
| AMS39129.1 | AMS41723.1 | AA2016_0187 | AA2016_2798 | Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cystathionine gamma-lyase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. | 0.969 |
| AMS39129.1 | AMS41957.1 | AA2016_0187 | AA2016_3033 | Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methionine synthase; Pfam:pfam02574 Homocysteine S-methyltransferase. | 0.956 |
| AMS39129.1 | AMS42929.1 | AA2016_0187 | AA2016_4012 | Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | O-acetylhomoserine aminocarboxypropyltransferase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. | 0.953 |
| AMS39129.1 | AMS43012.1 | AA2016_0187 | AA2016_4095 | Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 5,10-methylenetetrahydrofolate reductase. | 0.989 |
| AMS39129.1 | AMS43155.1 | AA2016_0187 | AA2016_4239 | Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cystathionine beta-lyase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. | 0.969 |
| AMS39129.1 | metH_2 | AA2016_0187 | AA2016_3011 | Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methyltetrahydrofolate:corrinoid methyltransferase; Pfam:pfam00809 Pterin binding enzyme. | 0.955 |
| AMS39129.1 | metZ | AA2016_0187 | AA2016_5304 | Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.969 |
| AMS39506.1 | AMS39129.1 | AA2016_0567 | AA2016_0187 | Cystathionine beta-lyase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. | Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.969 |
| AMS39506.1 | AMS41572.1 | AA2016_0567 | AA2016_2647 | Cystathionine beta-lyase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. | metFprotein; Pfam:pfam02219 Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.537 |
| AMS39506.1 | AMS41708.1 | AA2016_0567 | AA2016_2783 | Cystathionine beta-lyase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. | Pfam:pfam02219 Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.564 |
| AMS39506.1 | AMS41723.1 | AA2016_0567 | AA2016_2798 | Cystathionine beta-lyase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. | Cystathionine gamma-lyase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. | 0.922 |
| AMS39506.1 | AMS41957.1 | AA2016_0567 | AA2016_3033 | Cystathionine beta-lyase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. | Methionine synthase; Pfam:pfam02574 Homocysteine S-methyltransferase. | 0.940 |
| AMS39506.1 | AMS42929.1 | AA2016_0567 | AA2016_4012 | Cystathionine beta-lyase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. | O-acetylhomoserine aminocarboxypropyltransferase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. | 0.866 |
| AMS39506.1 | AMS43012.1 | AA2016_0567 | AA2016_4095 | Cystathionine beta-lyase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. | 5,10-methylenetetrahydrofolate reductase. | 0.537 |
| AMS39506.1 | AMS43155.1 | AA2016_0567 | AA2016_4239 | Cystathionine beta-lyase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. | Cystathionine beta-lyase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. | 0.920 |
| AMS39506.1 | metH_2 | AA2016_0567 | AA2016_3011 | Cystathionine beta-lyase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. | Methyltetrahydrofolate:corrinoid methyltransferase; Pfam:pfam00809 Pterin binding enzyme. | 0.921 |
| AMS39506.1 | metZ | AA2016_0567 | AA2016_5304 | Cystathionine beta-lyase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.831 |