| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMS39488.1 | AMS42948.1 | AA2016_0549 | AA2016_4031 | Pfam:pfam00908 dTDP-4-dehydrorhamnose 3,5-epimerase. | UDP-phosphate glucose phosphotransferase; Pfam:pfam02397 Bacterial sugar transferase. | 0.763 |
| AMS39488.1 | glnD | AA2016_0549 | AA2016_0547 | Pfam:pfam00908 dTDP-4-dehydrorhamnose 3,5-epimerase. | protein-PII uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | 0.407 |
| AMS39488.1 | murJ | AA2016_0549 | AA2016_0548 | Pfam:pfam00908 dTDP-4-dehydrorhamnose 3,5-epimerase. | Multidrug transporter MurJ; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.567 |
| AMS39488.1 | trpS | AA2016_0549 | AA2016_0552 | Pfam:pfam00908 dTDP-4-dehydrorhamnose 3,5-epimerase. | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.527 |
| AMS41727.1 | AMS41732.1 | AA2016_2802 | AA2016_2807 | Cell division protein; Pfam:pfam00905 Penicillin binding protein transpeptidase domain. | Pfam:pfam01098 Cell cycle protein; Belongs to the SEDS family. | 0.985 |
| AMS41727.1 | murC | AA2016_2802 | AA2016_2809 | Cell division protein; Pfam:pfam00905 Penicillin binding protein transpeptidase domain. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.910 |
| AMS41727.1 | murG | AA2016_2802 | AA2016_2808 | Cell division protein; Pfam:pfam00905 Penicillin binding protein transpeptidase domain. | UDP-diphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.844 |
| AMS41727.1 | murJ | AA2016_2802 | AA2016_0548 | Cell division protein; Pfam:pfam00905 Penicillin binding protein transpeptidase domain. | Multidrug transporter MurJ; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.560 |
| AMS41727.1 | rpoD | AA2016_2802 | AA2016_2578 | Cell division protein; Pfam:pfam00905 Penicillin binding protein transpeptidase domain. | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.577 |
| AMS41732.1 | AMS41727.1 | AA2016_2807 | AA2016_2802 | Pfam:pfam01098 Cell cycle protein; Belongs to the SEDS family. | Cell division protein; Pfam:pfam00905 Penicillin binding protein transpeptidase domain. | 0.985 |
| AMS41732.1 | murC | AA2016_2807 | AA2016_2809 | Pfam:pfam01098 Cell cycle protein; Belongs to the SEDS family. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.993 |
| AMS41732.1 | murG | AA2016_2807 | AA2016_2808 | Pfam:pfam01098 Cell cycle protein; Belongs to the SEDS family. | UDP-diphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.990 |
| AMS41732.1 | murJ | AA2016_2807 | AA2016_0548 | Pfam:pfam01098 Cell cycle protein; Belongs to the SEDS family. | Multidrug transporter MurJ; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.621 |
| AMS41732.1 | rpoD | AA2016_2807 | AA2016_2578 | Pfam:pfam01098 Cell cycle protein; Belongs to the SEDS family. | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.566 |
| AMS42948.1 | AMS39488.1 | AA2016_4031 | AA2016_0549 | UDP-phosphate glucose phosphotransferase; Pfam:pfam02397 Bacterial sugar transferase. | Pfam:pfam00908 dTDP-4-dehydrorhamnose 3,5-epimerase. | 0.763 |
| AMS42948.1 | murC | AA2016_4031 | AA2016_2809 | UDP-phosphate glucose phosphotransferase; Pfam:pfam02397 Bacterial sugar transferase. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.433 |
| AMS42948.1 | murJ | AA2016_4031 | AA2016_0548 | UDP-phosphate glucose phosphotransferase; Pfam:pfam02397 Bacterial sugar transferase. | Multidrug transporter MurJ; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.584 |
| glnD | AMS39488.1 | AA2016_0547 | AA2016_0549 | protein-PII uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | Pfam:pfam00908 dTDP-4-dehydrorhamnose 3,5-epimerase. | 0.407 |
| glnD | murJ | AA2016_0547 | AA2016_0548 | protein-PII uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | Multidrug transporter MurJ; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.788 |
| glnD | trpS | AA2016_0547 | AA2016_0552 | protein-PII uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.494 |