Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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glcB-2Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (725 aa)    
Predicted Functional Partners:
icl
Pfam:pfam00463 Isocitrate lyase family.
 
 
 0.989
AMS39462.1
Malic enzyme; Pfam:pfam01515 Phosphate acetyl/butaryl transferase.
  
 
 0.975
AMS42802.1
Malic enzyme; Pfam:pfam01515 Phosphate acetyl/butaryl transferase.
  
 
 0.975
AMS41509.1
Hypothetical protein; Pfam:pfam00285 Citrate synthase; Belongs to the citrate synthase family.
  
 0.951
AMS41510.1
Pfam:pfam00285 Citrate synthase; Belongs to the citrate synthase family.
   
 0.949
AMS42729.1
Pfam:pfam00285 Citrate synthase; Belongs to the citrate synthase family.
   
 0.949
acsA
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 0.932
AMS40708.1
AMP-dependent synthetase; Pfam:pfam00501 AMP-binding enzyme.
   
 0.932
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
   
 0.930
AMS44055.1
2-hydroxy-acid oxidase; Pfam:pfam02754 Cysteine-rich domain.
  
 
 0.926
Your Current Organism:
Aminobacter aminovorans
NCBI taxonomy Id: 83263
Other names: A. aminovorans, ATCC 23314, ATCC 29600, Aminobacter heintzii, CCUG 2081, CIP 106737, Chelatobacter heintzii, DSM 10368, DSM 7048, JCM 7852, KCTC 2477, LMG 2122, LMG:2122, NCCB 26039, NCIB 9039, NCIB:9039, NCIMB 9039, NCTC 10684, Pseudomonas aminovorans, VKM B-2058
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