| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMS39129.1 | AMS39505.1 | AA2016_0187 | AA2016_0566 | Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cystathionine beta-synthase; Pfam:pfam00291 Pyridoxal-phosphate dependent enzyme. | 0.942 |
| AMS39129.1 | AMS41957.1 | AA2016_0187 | AA2016_3033 | Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methionine synthase; Pfam:pfam02574 Homocysteine S-methyltransferase. | 0.953 |
| AMS39129.1 | AMS42929.1 | AA2016_0187 | AA2016_4012 | Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | O-acetylhomoserine aminocarboxypropyltransferase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. | 0.961 |
| AMS39129.1 | AMS43155.1 | AA2016_0187 | AA2016_4239 | Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cystathionine beta-lyase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. | 0.959 |
| AMS39129.1 | ahcY | AA2016_0187 | AA2016_0763 | Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.960 |
| AMS39129.1 | metH_2 | AA2016_0187 | AA2016_3011 | Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methyltetrahydrofolate:corrinoid methyltransferase; Pfam:pfam00809 Pterin binding enzyme. | 0.956 |
| AMS39129.1 | metZ | AA2016_0187 | AA2016_5304 | Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.959 |
| AMS39505.1 | AMS39129.1 | AA2016_0566 | AA2016_0187 | Cystathionine beta-synthase; Pfam:pfam00291 Pyridoxal-phosphate dependent enzyme. | Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.942 |
| AMS39505.1 | AMS41957.1 | AA2016_0566 | AA2016_3033 | Cystathionine beta-synthase; Pfam:pfam00291 Pyridoxal-phosphate dependent enzyme. | Methionine synthase; Pfam:pfam02574 Homocysteine S-methyltransferase. | 0.916 |
| AMS39505.1 | AMS42929.1 | AA2016_0566 | AA2016_4012 | Cystathionine beta-synthase; Pfam:pfam00291 Pyridoxal-phosphate dependent enzyme. | O-acetylhomoserine aminocarboxypropyltransferase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. | 0.959 |
| AMS39505.1 | AMS43155.1 | AA2016_0566 | AA2016_4239 | Cystathionine beta-synthase; Pfam:pfam00291 Pyridoxal-phosphate dependent enzyme. | Cystathionine beta-lyase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. | 0.979 |
| AMS39505.1 | ahcY | AA2016_0566 | AA2016_0763 | Cystathionine beta-synthase; Pfam:pfam00291 Pyridoxal-phosphate dependent enzyme. | S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.945 |
| AMS39505.1 | metH_2 | AA2016_0566 | AA2016_3011 | Cystathionine beta-synthase; Pfam:pfam00291 Pyridoxal-phosphate dependent enzyme. | Methyltetrahydrofolate:corrinoid methyltransferase; Pfam:pfam00809 Pterin binding enzyme. | 0.914 |
| AMS39505.1 | metZ | AA2016_0566 | AA2016_5304 | Cystathionine beta-synthase; Pfam:pfam00291 Pyridoxal-phosphate dependent enzyme. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.977 |
| AMS39588.1 | AMS41186.1 | AA2016_0649 | AA2016_2258 | Cytosine deaminase-like metal-dependent hydrolase; Pfam:pfam01979 Amidohydrolase family. | Modification methylase; Pfam:pfam00145 C-5 cytosine-specific DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.904 |
| AMS39588.1 | AMS44039.1 | AA2016_0649 | AA2016_5132 | Cytosine deaminase-like metal-dependent hydrolase; Pfam:pfam01979 Amidohydrolase family. | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Pfam:pfam01048 Phosphorylase superfamily. | 0.905 |
| AMS39588.1 | ahcY | AA2016_0649 | AA2016_0763 | Cytosine deaminase-like metal-dependent hydrolase; Pfam:pfam01979 Amidohydrolase family. | S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.925 |
| AMS41186.1 | AMS39588.1 | AA2016_2258 | AA2016_0649 | Modification methylase; Pfam:pfam00145 C-5 cytosine-specific DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Cytosine deaminase-like metal-dependent hydrolase; Pfam:pfam01979 Amidohydrolase family. | 0.904 |
| AMS41186.1 | AMS44039.1 | AA2016_2258 | AA2016_5132 | Modification methylase; Pfam:pfam00145 C-5 cytosine-specific DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Pfam:pfam01048 Phosphorylase superfamily. | 0.903 |
| AMS41186.1 | ahcY | AA2016_2258 | AA2016_0763 | Modification methylase; Pfam:pfam00145 C-5 cytosine-specific DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.908 |