STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMS39874.1Pfam:pfam00171 Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family. (504 aa)    
Predicted Functional Partners:
acsA
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.932
AMS40708.1
AMP-dependent synthetase; Pfam:pfam00501 AMP-binding enzyme.
  
 0.932
AMS40118.1
Pfam:pfam00202 Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.924
AMS43046.1
Pfam:pfam00202 Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.924
AMS44230.1
Pfam:pfam02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.
  
 0.921
AMS40612.1
Pfam:pfam08240 Alcohol dehydrogenase GroES-like domain; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
 
 0.919
ackA
Hypothetical protein; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
  
 
 0.918
AMS41971.1
3-hydroxyisobutyrate dehydrogenase; Pfam:pfam03446 NAD binding domain of 6-phosphogluconate dehydrogenase; Belongs to the HIBADH-related family.
  
 
 0.912
AMS42149.1
Hypothetical protein; Pfam:pfam08240 Alcohol dehydrogenase GroES-like domain.
  
 
 0.912
AMS39104.1
Amidase; Pfam:pfam01425 Amidase.
   
 0.911
Your Current Organism:
Aminobacter aminovorans
NCBI taxonomy Id: 83263
Other names: A. aminovorans, ATCC 23314, ATCC 29600, Aminobacter heintzii, CCUG 2081, CIP 106737, Chelatobacter heintzii, DSM 10368, DSM 7048, JCM 7852, KCTC 2477, LMG 2122, LMG:2122, NCCB 26039, NCIB 9039, NCIB:9039, NCIMB 9039, NCTC 10684, Pseudomonas aminovorans, VKM B-2058
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