STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMS39940.1Pfam:pfam01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit. (131 aa)    
Predicted Functional Partners:
AMS39939.1
Pfam:pfam01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit.
 
 0.999
AMS39941.1
Succinate dehydrogenase; Pfam:pfam00890 FAD binding domain; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
 
 0.999
sdhB
Succinate dehydrogenase iron-sulfur subunit; Pfam:pfam13085 2Fe-2S iron-sulfur cluster binding domain; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
 
 0.999
sucC
malate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.987
sucD
Succinyl-CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.954
fumC
Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 
 0.924
AMS39526.1
Pfam:pfam00171 Aldehyde dehydrogenase family.
   
 
 0.906
AMS41998.1
Succinate-semialdehyde dehdyrogenase; Pfam:pfam00171 Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family.
   
 
 0.906
AMS42896.1
Pfam:pfam00171 Aldehyde dehydrogenase family.
   
 
 0.906
AMS43047.1
Succinic semialdehyde dehydrogenase; Pfam:pfam00171 Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family.
   
 
 0.906
Your Current Organism:
Aminobacter aminovorans
NCBI taxonomy Id: 83263
Other names: A. aminovorans, ATCC 23314, ATCC 29600, Aminobacter heintzii, CCUG 2081, CIP 106737, Chelatobacter heintzii, DSM 10368, DSM 7048, JCM 7852, KCTC 2477, LMG 2122, LMG:2122, NCCB 26039, NCIB 9039, NCIB:9039, NCIMB 9039, NCTC 10684, Pseudomonas aminovorans, VKM B-2058
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