Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AMS40073.1Diaminopropionate ammonia-lyase; Pfam:pfam00291 Pyridoxal-phosphate dependent enzyme. (402 aa)    
Predicted Functional Partners:
AMS40074.1
Pyridoxal-5'-phosphate-dependent protein subunit beta; Pfam:pfam00291 Pyridoxal-phosphate dependent enzyme.
 
  
 0.806
AMS41983.1
Succinyl-diaminopimelate desuccinylase; Pfam:pfam01546 Peptidase family M20/M25/M40.
 
  
 0.784
AMS40081.1
Hypothetical protein; Pfam:pfam01546 Peptidase family M20/M25/M40.
  
 0.664
AMS40947.1
Glutamate synthase; Pfam:pfam01645 Conserved region in glutamate synthase.
  
 
 0.596
AMS40070.1
Hypothetical protein; Pfam:pfam02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Belongs to the TPP enzyme family.
  
 
 0.527
AMS40072.1
AsnC family transcriptional regulator; Pfam:pfam07729 FCD domain.
       0.506
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
  
 0.487
ilvD
Pfam:pfam00920 Dehydratase family; Belongs to the IlvD/Edd family.
  
 
 0.486
AMS40133.1
Pfam:pfam00920 Dehydratase family; Belongs to the IlvD/Edd family.
  
 
 0.486
AMS43849.1
Pfam:pfam00920 Dehydratase family; Belongs to the IlvD/Edd family.
  
 
 0.486
Your Current Organism:
Aminobacter aminovorans
NCBI taxonomy Id: 83263
Other names: A. aminovorans, ATCC 23314, ATCC 29600, Aminobacter heintzii, CCUG 2081, CIP 106737, Chelatobacter heintzii, DSM 10368, DSM 7048, JCM 7852, KCTC 2477, LMG 2122, LMG:2122, NCCB 26039, NCIB 9039, NCIB:9039, NCIMB 9039, NCTC 10684, Pseudomonas aminovorans, VKM B-2058
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.