Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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AMS40269.1Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1152 aa)    
Predicted Functional Partners:
AMS40397.1
Pfam:pfam00224 Pyruvate kinase, barrel domain; Belongs to the pyruvate kinase family.
   
 0.963
AMS39462.1
Malic enzyme; Pfam:pfam01515 Phosphate acetyl/butaryl transferase.
   
 0.961
AMS42802.1
Malic enzyme; Pfam:pfam01515 Phosphate acetyl/butaryl transferase.
   
 0.961
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.948
pckA
Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
    
 0.938
AMS41509.1
Hypothetical protein; Pfam:pfam00285 Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.934
AMS43682.1
Pyruvate phosphate dikinase; Pfam:pfam02896 PEP-utilizing enzyme, TIM barrel domain; Belongs to the PEP-utilizing enzyme family.
    
 0.931
AMS41510.1
Pfam:pfam00285 Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.928
AMS42028.1
Pfam:pfam01070 FMN-dependent dehydrogenase.
  
 
 0.928
AMS42729.1
Pfam:pfam00285 Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.928
Your Current Organism:
Aminobacter aminovorans
NCBI taxonomy Id: 83263
Other names: A. aminovorans, ATCC 23314, ATCC 29600, Aminobacter heintzii, CCUG 2081, CIP 106737, Chelatobacter heintzii, DSM 10368, DSM 7048, JCM 7852, KCTC 2477, LMG 2122, LMG:2122, NCCB 26039, NCIB 9039, NCIB:9039, NCIMB 9039, NCTC 10684, Pseudomonas aminovorans, VKM B-2058
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