Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AMS40399.1TPR repeat-containing protein; Pfam:pfam13414 TPR repeat. (193 aa)    
Predicted Functional Partners:
AMS40680.1
Hypothetical protein; Pfam:pfam13779 Domain of unknown function (DUF4175).
 
   
 0.714
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 0.695
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 0.668
AMS41293.1
ATPase AAA; Pfam:pfam00004 ATPase family associated with various cellular activities (AAA).
  
 0.663
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 0.654
AMS40398.1
Hypothetical protein; Pfam:pfam12697 Alpha/beta hydrolase family.
 
   0.651
AMS41312.1
RNA-binding protein; Pfam:pfam13709 Domain of unknown function (DUF4159).
  
     0.641
AMS43288.1
Cysteine desulfurase; Pfam:pfam12796 Ankyrin repeats (3 copies).
 
 0.637
AMS41311.1
Pfam:pfam07090 Protein of unknown function (DUF1355).
 
     0.619
AMS43787.1
Tetratricopeptide TPR_1 repeat-containing protein; Pfam:pfam13414 TPR repeat.
 
 
 
 0.616
Your Current Organism:
Aminobacter aminovorans
NCBI taxonomy Id: 83263
Other names: A. aminovorans, ATCC 23314, ATCC 29600, Aminobacter heintzii, CCUG 2081, CIP 106737, Chelatobacter heintzii, DSM 10368, DSM 7048, JCM 7852, KCTC 2477, LMG 2122, LMG:2122, NCCB 26039, NCIB 9039, NCIB:9039, NCIMB 9039, NCTC 10684, Pseudomonas aminovorans, VKM B-2058
Server load: low (24%) [HD]