Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AMS40429.1acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family. (384 aa)    
Predicted Functional Partners:
AMS42575.1
Hypothetical protein; Pfam:pfam02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.
 0.998
AMS44230.1
Pfam:pfam02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.
 
 0.998
AMS40690.1
Pfam:pfam02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.
 0.984
AMS40811.1
Pfam:pfam00441 Acyl-CoA dehydrogenase, C-terminal domain.
  
 0.952
AMS42572.1
Pfam:pfam00441 Acyl-CoA dehydrogenase, C-terminal domain.
  
 0.952
AMS41509.1
Hypothetical protein; Pfam:pfam00285 Citrate synthase; Belongs to the citrate synthase family.
  
 0.943
AMS41510.1
Pfam:pfam00285 Citrate synthase; Belongs to the citrate synthase family.
  
 0.940
AMS42729.1
Pfam:pfam00285 Citrate synthase; Belongs to the citrate synthase family.
  
 0.940
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 
 0.928
AMS43474.1
2-isopropylmalate synthase; Pfam:pfam00682 HMGL-like; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.928
Your Current Organism:
Aminobacter aminovorans
NCBI taxonomy Id: 83263
Other names: A. aminovorans, ATCC 23314, ATCC 29600, Aminobacter heintzii, CCUG 2081, CIP 106737, Chelatobacter heintzii, DSM 10368, DSM 7048, JCM 7852, KCTC 2477, LMG 2122, LMG:2122, NCCB 26039, NCIB 9039, NCIB:9039, NCIMB 9039, NCTC 10684, Pseudomonas aminovorans, VKM B-2058
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