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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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thiCPhosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (608 aa)    
Predicted Functional Partners:
AMS40615.1
Pfam:pfam08543 Phosphomethylpyrimidine kinase.
 
 
 0.998
thiG
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
  
 0.992
AMS40618.1
Hypothetical protein; Pfam:pfam02597 ThiS family.
  
  
 0.979
AMS40616.1
Thiamine-phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
 
  
 0.967
AMS38947.1
Thiamine biosynthesis protein ThiF; Pfam:pfam00899 ThiF family.
 
  
 0.857
AMS40619.1
Hypothetical protein; Pfam:pfam01266 FAD dependent oxidoreductase.
  
  
 0.856
purM
Phosphoribosylaminoimidazole synthetase; Pfam:pfam02769 AIR synthase related protein, C-terminal domain.
    
 0.815
purK
Phosphoribosylaminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
    
  0.802
AMS40348.1
Thiamine-phosphate pyrophosphorylase; Pfam:pfam02581 Thiamine monophosphate synthase/TENI.
  
  
 0.800
AMS41411.1
Pfam:pfam11335 Protein of unknown function (DUF3137).
  
  
 0.782
Your Current Organism:
Aminobacter aminovorans
NCBI taxonomy Id: 83263
Other names: A. aminovorans, ATCC 23314, ATCC 29600, Aminobacter heintzii, CCUG 2081, CIP 106737, Chelatobacter heintzii, DSM 10368, DSM 7048, JCM 7852, KCTC 2477, LMG 2122, LMG:2122, NCCB 26039, NCIB 9039, NCIB:9039, NCIMB 9039, NCTC 10684, Pseudomonas aminovorans, VKM B-2058
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