Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AMS40669.1Gamma-glutamyl cyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (172 aa)    
Predicted Functional Partners:
AMS41885.1
ChaC family protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
  
  
 
0.915
AMS42070.1
Glutathione reductase; Maintains high levels of reduced glutathione.
  
  
 0.912
gshB
Pfam:pfam02955 Prokaryotic glutathione synthetase, ATP-grasp domain; Belongs to the prokaryotic GSH synthase family.
    
 0.907
AMS43586.1
Pfam:pfam11940 Domain of unknown function (DUF3458).
    
 0.905
AMS39275.1
Gamma-glutamyltransferase; Pfam:pfam01019 Gamma-glutamyltranspeptidase.
   
 
 0.904
AMS42877.1
Hypothetical protein; Pfam:pfam01019 Gamma-glutamyltranspeptidase.
   
 
 0.904
AMS39545.1
5-oxoprolinase; Pfam:pfam02538 Hydantoinase B/oxoprolinase.
     
 0.903
pepA
Aminopeptidase A; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
     
 0.900
AMS43736.1
Alkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
     
  0.900
AMS44393.1
Cytochrome C oxidase subunit II; Pfam:pfam00883 Cytosol aminopeptidase family, catalytic domain; Belongs to the peptidase M17 family.
     
 0.900
Your Current Organism:
Aminobacter aminovorans
NCBI taxonomy Id: 83263
Other names: A. aminovorans, ATCC 23314, ATCC 29600, Aminobacter heintzii, CCUG 2081, CIP 106737, Chelatobacter heintzii, DSM 10368, DSM 7048, JCM 7852, KCTC 2477, LMG 2122, LMG:2122, NCCB 26039, NCIB 9039, NCIB:9039, NCIMB 9039, NCTC 10684, Pseudomonas aminovorans, VKM B-2058
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