Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AMS40918.1Pfam:pfam00171 Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family. (506 aa)    
Predicted Functional Partners:
AMS40917.1
Pfam:pfam00378 Enoyl-CoA hydratase/isomerase family; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.857
AMS40914.1
LacI family transcriptional regulator; Pfam:pfam13377 Periplasmic binding protein-like domain.
   
 
 0.830
AMS40916.1
CoA-transferase; CoA transferase having broad substrate specificity for short- chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons. Belongs to the 3-oxoacid CoA-transferase family.
     
 0.817
AMS40915.1
Pfam:pfam01408 Oxidoreductase family, NAD-binding Rossmann fold.
  
  
 0.778
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
 
      0.670
AMS40919.1
Sugar ABC transporter substrate-binding protein; Pfam:pfam01547 Bacterial extracellular solute-binding protein.
  
    0.554
AMS40923.1
Pfam:pfam05199 GMC oxidoreductase.
 
  
 0.480
AMS42575.1
Hypothetical protein; Pfam:pfam02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.
  
 0.460
AMS44230.1
Pfam:pfam02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.
  
 0.460
fumC
Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
 0.447
Your Current Organism:
Aminobacter aminovorans
NCBI taxonomy Id: 83263
Other names: A. aminovorans, ATCC 23314, ATCC 29600, Aminobacter heintzii, CCUG 2081, CIP 106737, Chelatobacter heintzii, DSM 10368, DSM 7048, JCM 7852, KCTC 2477, LMG 2122, LMG:2122, NCCB 26039, NCIB 9039, NCIB:9039, NCIMB 9039, NCTC 10684, Pseudomonas aminovorans, VKM B-2058
Server load: low (14%) [HD]