| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMS39211.1 | AMS40105.1 | AA2016_0271 | AA2016_1169 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Hypothetical protein; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. | 0.698 |
| AMS39211.1 | AMS40132.1 | AA2016_0271 | AA2016_1196 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Pyridine nucleotide-disulfide oxidoreductase domain protein; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. | 0.690 |
| AMS39211.1 | AMS43707.1 | AA2016_0271 | AA2016_4798 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Nitrate reductase; Pfam:pfam00384 Molybdopterin oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | 0.436 |
| AMS39211.1 | AMS43709.1 | AA2016_0271 | AA2016_4800 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Nitrite reductase (NAD(P)H), large subunit; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.630 |
| AMS39211.1 | AMS44286.1 | AA2016_0271 | AA2016_5380 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Hypothetical protein; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. | 0.696 |
| AMS39211.1 | ndoA | AA2016_0271 | AA2016_2136 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | MocE; Pfam:pfam00355 Rieske [2Fe-2S] domain. | 0.799 |
| AMS40105.1 | AMS39211.1 | AA2016_1169 | AA2016_0271 | Hypothetical protein; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.698 |
| AMS40105.1 | AMS40132.1 | AA2016_1169 | AA2016_1196 | Hypothetical protein; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. | Pyridine nucleotide-disulfide oxidoreductase domain protein; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. | 0.910 |
| AMS40105.1 | AMS41065.1 | AA2016_1169 | AA2016_2135 | Hypothetical protein; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. | Ferredoxin reductase; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. | 0.920 |
| AMS40105.1 | AMS43707.1 | AA2016_1169 | AA2016_4798 | Hypothetical protein; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. | Nitrate reductase; Pfam:pfam00384 Molybdopterin oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | 0.946 |
| AMS40105.1 | AMS44286.1 | AA2016_1169 | AA2016_5380 | Hypothetical protein; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. | Hypothetical protein; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. | 0.916 |
| AMS40105.1 | ndoA | AA2016_1169 | AA2016_2136 | Hypothetical protein; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. | MocE; Pfam:pfam00355 Rieske [2Fe-2S] domain. | 0.690 |
| AMS40132.1 | AMS39211.1 | AA2016_1196 | AA2016_0271 | Pyridine nucleotide-disulfide oxidoreductase domain protein; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.690 |
| AMS40132.1 | AMS40105.1 | AA2016_1196 | AA2016_1169 | Pyridine nucleotide-disulfide oxidoreductase domain protein; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. | Hypothetical protein; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. | 0.910 |
| AMS40132.1 | AMS41065.1 | AA2016_1196 | AA2016_2135 | Pyridine nucleotide-disulfide oxidoreductase domain protein; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. | Ferredoxin reductase; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. | 0.919 |
| AMS40132.1 | AMS43707.1 | AA2016_1196 | AA2016_4798 | Pyridine nucleotide-disulfide oxidoreductase domain protein; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. | Nitrate reductase; Pfam:pfam00384 Molybdopterin oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | 0.693 |
| AMS40132.1 | AMS44286.1 | AA2016_1196 | AA2016_5380 | Pyridine nucleotide-disulfide oxidoreductase domain protein; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. | Hypothetical protein; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. | 0.916 |
| AMS40132.1 | ndoA | AA2016_1196 | AA2016_2136 | Pyridine nucleotide-disulfide oxidoreductase domain protein; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. | MocE; Pfam:pfam00355 Rieske [2Fe-2S] domain. | 0.692 |
| AMS41065.1 | AMS40105.1 | AA2016_2135 | AA2016_1169 | Ferredoxin reductase; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. | Hypothetical protein; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. | 0.920 |
| AMS41065.1 | AMS40132.1 | AA2016_2135 | AA2016_1196 | Ferredoxin reductase; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. | Pyridine nucleotide-disulfide oxidoreductase domain protein; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. | 0.919 |