STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMS41260.1Hypothetical protein; Pfam:pfam12697 Alpha/beta hydrolase family. (266 aa)    
Predicted Functional Partners:
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 
 0.945
AMS41509.1
Hypothetical protein; Pfam:pfam00285 Citrate synthase; Belongs to the citrate synthase family.
  
 0.915
AMS43474.1
2-isopropylmalate synthase; Pfam:pfam00682 HMGL-like; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.915
pdhA
Pyruvate dehydrogenase E1 subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.914
AMS41510.1
Pfam:pfam00285 Citrate synthase; Belongs to the citrate synthase family.
  
 0.911
AMS42729.1
Pfam:pfam00285 Citrate synthase; Belongs to the citrate synthase family.
  
 0.911
AMS42707.1
Branched-chain alpha-keto acid dehydrogenase subunit E2; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
   
 0.910
AMS40292.1
acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.908
AMS40429.1
acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.908
AMS42569.1
Hypothetical protein; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.908
Your Current Organism:
Aminobacter aminovorans
NCBI taxonomy Id: 83263
Other names: A. aminovorans, ATCC 23314, ATCC 29600, Aminobacter heintzii, CCUG 2081, CIP 106737, Chelatobacter heintzii, DSM 10368, DSM 7048, JCM 7852, KCTC 2477, LMG 2122, LMG:2122, NCCB 26039, NCIB 9039, NCIB:9039, NCIMB 9039, NCTC 10684, Pseudomonas aminovorans, VKM B-2058
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