close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMS41287.1Ser/Thr protein phosphatase family protein; Pfam:pfam02872 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family. (684 aa)    
Predicted Functional Partners:
AMS39070.1
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
 
 
 0.643
AMS39064.1
Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.
 
  
 0.610
ade
Pfam:pfam13382 Adenine deaminase C-terminal domain; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
  
  
 0.566
guaB
Inosine-5`-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.563
AMS43007.1
Pfam:pfam00962 Adenosine/AMP deaminase.
    
 0.556
deoD
Hypothetical protein; Pfam:pfam01048 Phosphorylase superfamily.
    
 0.525
AMS42216.1
Inosine-5-monophosphate dehydrogenase; Pfam:pfam00571 CBS domain.
     
  0.499
AMS41288.1
Hypothetical protein; Pfam:pfam13411 MerR HTH family regulatory protein.
       0.495
AMS41289.1
Transcriptional regulator, MerR family protein; Pfam:pfam07739 TipAS antibiotic-recognition domain.
       0.495
AMS43134.1
Multi antimicrobial extrusion protein MatE; Pfam:pfam01554 MatE.
 
 
 0.415
Your Current Organism:
Aminobacter aminovorans
NCBI taxonomy Id: 83263
Other names: A. aminovorans, ATCC 23314, ATCC 29600, Aminobacter heintzii, CCUG 2081, CIP 106737, Chelatobacter heintzii, DSM 10368, DSM 7048, JCM 7852, KCTC 2477, LMG 2122, LMG:2122, NCCB 26039, NCIB 9039, NCIB:9039, NCIMB 9039, NCTC 10684, Pseudomonas aminovorans, VKM B-2058
Server load: low (26%) [HD]