| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMS38978.1 | AMS39129.1 | AA2016_0035 | AA2016_0187 | Pfam:pfam02773 S-adenosylmethionine synthetase, C-terminal domain; Belongs to the AdoMet synthase family. | Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.957 |
| AMS38978.1 | AMS41359.1 | AA2016_0035 | AA2016_2433 | Pfam:pfam02773 S-adenosylmethionine synthetase, C-terminal domain; Belongs to the AdoMet synthase family. | Methionine ABC transporter substrate-binding protein; Pfam:pfam03180 NLPA lipoprotein; Belongs to the nlpA lipoprotein family. | 0.553 |
| AMS38978.1 | AMS41572.1 | AA2016_0035 | AA2016_2647 | Pfam:pfam02773 S-adenosylmethionine synthetase, C-terminal domain; Belongs to the AdoMet synthase family. | metFprotein; Pfam:pfam02219 Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.595 |
| AMS38978.1 | AMS41708.1 | AA2016_0035 | AA2016_2783 | Pfam:pfam02773 S-adenosylmethionine synthetase, C-terminal domain; Belongs to the AdoMet synthase family. | Pfam:pfam02219 Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.763 |
| AMS38978.1 | AMS41936.1 | AA2016_0035 | AA2016_3012 | Pfam:pfam02773 S-adenosylmethionine synthetase, C-terminal domain; Belongs to the AdoMet synthase family. | Pfam:pfam02219 Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.595 |
| AMS38978.1 | AMS41937.1 | AA2016_0035 | AA2016_3013 | Pfam:pfam02773 S-adenosylmethionine synthetase, C-terminal domain; Belongs to the AdoMet synthase family. | Pfam:pfam12225 Methylene-tetrahydrofolate reductase C terminal. | 0.566 |
| AMS38978.1 | AMS43012.1 | AA2016_0035 | AA2016_4095 | Pfam:pfam02773 S-adenosylmethionine synthetase, C-terminal domain; Belongs to the AdoMet synthase family. | 5,10-methylenetetrahydrofolate reductase. | 0.595 |
| AMS38978.1 | metAA | AA2016_0035 | AA2016_1733 | Pfam:pfam02773 S-adenosylmethionine synthetase, C-terminal domain; Belongs to the AdoMet synthase family. | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.678 |
| AMS38978.1 | metN | AA2016_0035 | AA2016_2434 | Pfam:pfam02773 S-adenosylmethionine synthetase, C-terminal domain; Belongs to the AdoMet synthase family. | Methionine ABC transporter ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | 0.706 |
| AMS39129.1 | AMS38978.1 | AA2016_0187 | AA2016_0035 | Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Pfam:pfam02773 S-adenosylmethionine synthetase, C-terminal domain; Belongs to the AdoMet synthase family. | 0.957 |
| AMS39129.1 | AMS41359.1 | AA2016_0187 | AA2016_2433 | Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methionine ABC transporter substrate-binding protein; Pfam:pfam03180 NLPA lipoprotein; Belongs to the nlpA lipoprotein family. | 0.431 |
| AMS39129.1 | AMS41572.1 | AA2016_0187 | AA2016_2647 | Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | metFprotein; Pfam:pfam02219 Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.988 |
| AMS39129.1 | AMS41708.1 | AA2016_0187 | AA2016_2783 | Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Pfam:pfam02219 Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.991 |
| AMS39129.1 | AMS41936.1 | AA2016_0187 | AA2016_3012 | Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Pfam:pfam02219 Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.988 |
| AMS39129.1 | AMS41937.1 | AA2016_0187 | AA2016_3013 | Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Pfam:pfam12225 Methylene-tetrahydrofolate reductase C terminal. | 0.841 |
| AMS39129.1 | AMS43012.1 | AA2016_0187 | AA2016_4095 | Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 5,10-methylenetetrahydrofolate reductase. | 0.988 |
| AMS39129.1 | metAA | AA2016_0187 | AA2016_1733 | Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.868 |
| AMS39129.1 | metN | AA2016_0187 | AA2016_2434 | Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methionine ABC transporter ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | 0.455 |
| AMS41359.1 | AMS38978.1 | AA2016_2433 | AA2016_0035 | Methionine ABC transporter substrate-binding protein; Pfam:pfam03180 NLPA lipoprotein; Belongs to the nlpA lipoprotein family. | Pfam:pfam02773 S-adenosylmethionine synthetase, C-terminal domain; Belongs to the AdoMet synthase family. | 0.553 |
| AMS41359.1 | AMS39129.1 | AA2016_2433 | AA2016_0187 | Methionine ABC transporter substrate-binding protein; Pfam:pfam03180 NLPA lipoprotein; Belongs to the nlpA lipoprotein family. | Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.431 |