Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AMS41397.1Hypothetical protein; Pfam:pfam00291 Pyridoxal-phosphate dependent enzyme. (409 aa)    
Predicted Functional Partners:
AMS40081.1
Hypothetical protein; Pfam:pfam01546 Peptidase family M20/M25/M40.
  
 0.763
AMS41398.1
Leucine-responsive regulatory protein; Pfam:pfam01037 AsnC family.
 
   
 0.652
AMS40947.1
Glutamate synthase; Pfam:pfam01645 Conserved region in glutamate synthase.
  
 
 0.596
AMS41983.1
Succinyl-diaminopimelate desuccinylase; Pfam:pfam01546 Peptidase family M20/M25/M40.
 
  
 0.593
AMS41396.1
Hypothetical protein; Pfam:pfam00144 Beta-lactamase.
  
    0.547
AMS41395.1
Beta-lactamase; Pfam:pfam00144 Beta-lactamase.
  
    0.509
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
  
 0.487
ilvD
Pfam:pfam00920 Dehydratase family; Belongs to the IlvD/Edd family.
  
 
 0.486
AMS40133.1
Pfam:pfam00920 Dehydratase family; Belongs to the IlvD/Edd family.
  
 
 0.486
AMS43849.1
Pfam:pfam00920 Dehydratase family; Belongs to the IlvD/Edd family.
  
 
 0.486
Your Current Organism:
Aminobacter aminovorans
NCBI taxonomy Id: 83263
Other names: A. aminovorans, ATCC 23314, ATCC 29600, Aminobacter heintzii, CCUG 2081, CIP 106737, Chelatobacter heintzii, DSM 10368, DSM 7048, JCM 7852, KCTC 2477, LMG 2122, LMG:2122, NCCB 26039, NCIB 9039, NCIB:9039, NCIMB 9039, NCTC 10684, Pseudomonas aminovorans, VKM B-2058
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