Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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AMS41779.1Hypothetical protein; Pfam:pfam14415 Domain of unknown function (DUF4424). (339 aa)    
Predicted Functional Partners:
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
       0.792
AMS41780.1
Diacylglycerol kinase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
       0.659
AMS43518.1
Transcriptional regulator, repressor protein MphR(A).
  
     0.625
AMS38996.1
Pfam:pfam06532 Protein of unknown function (DUF1109).
  
     0.543
AMS41777.1
YHS domain protein.
       0.512
AMS39360.1
Hypothetical protein.
  
     0.511
AMS43054.1
Aminotransferase; Pfam:pfam01380 SIS domain.
  
     0.493
AMS43936.1
Copper binding protein; Pfam:pfam04234 CopC domain.
  
     0.472
AMS39878.1
Hypothetical protein; Pfam:pfam04234 CopC domain.
  
     0.452
AMS43919.1
Amicyanin; Pfam:pfam13473 Cupredoxin-like domain.
  
     0.426
Your Current Organism:
Aminobacter aminovorans
NCBI taxonomy Id: 83263
Other names: A. aminovorans, ATCC 23314, ATCC 29600, Aminobacter heintzii, CCUG 2081, CIP 106737, Chelatobacter heintzii, DSM 10368, DSM 7048, JCM 7852, KCTC 2477, LMG 2122, LMG:2122, NCCB 26039, NCIB 9039, NCIB:9039, NCIMB 9039, NCTC 10684, Pseudomonas aminovorans, VKM B-2058
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