Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
AMS41814.1Pfam:pfam00440 Bacterial regulatory proteins, tetR family. (217 aa)    
Predicted Functional Partners:
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
       0.746
AMS43604.1
Hypothetical protein.
  
     0.599
AMS42069.1
Pfam:pfam09832 Uncharacterized protein conserved in bacteria (DUF2059).
  
     0.514
AMS42982.1
Membrane protein; Pfam:pfam06271 RDD family.
  
     0.512
AMS43494.1
Pfam:pfam13316 Protein of unknown function (DUF4087).
  
     0.493
AMS41813.1
Hypothetical protein; Pfam:pfam03466 LysR substrate binding domain; Belongs to the LysR transcriptional regulatory family.
   
   0.486
AMS43779.1
Hypothetical protein.
  
     0.476
AMS44123.1
Hypothetical protein.
  
     0.458
AMS39824.1
Hypothetical protein; Pfam:pfam08410 Domain of unknown function (DUF1737).
  
    0.454
AMS42078.1
Hypothetical protein; Pfam:pfam10016 Predicted secreted protein (DUF2259).
  
     0.441
Your Current Organism:
Aminobacter aminovorans
NCBI taxonomy Id: 83263
Other names: A. aminovorans, ATCC 23314, ATCC 29600, Aminobacter heintzii, CCUG 2081, CIP 106737, Chelatobacter heintzii, DSM 10368, DSM 7048, JCM 7852, KCTC 2477, LMG 2122, LMG:2122, NCCB 26039, NCIB 9039, NCIB:9039, NCIMB 9039, NCTC 10684, Pseudomonas aminovorans, VKM B-2058
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