Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AMS41847.1Cobalamin biosynthesis protein CobG; Pfam:pfam03460 Nitrite/Sulfite reductase ferredoxin-like half domain. (505 aa)    
Predicted Functional Partners:
AMS41845.1
Precorrin-2 C20-methyltransferase; Pfam:pfam00590 Tetrapyrrole (Corrin/Porphyrin) Methylases; Belongs to the precorrin methyltransferase family.
 
 
 0.993
AMS41844.1
precorrin-3B C17-methyltransferase; Pfam:pfam00590 Tetrapyrrole (Corrin/Porphyrin) Methylases.
 
 
 0.991
cysN
Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
  
  
 0.989
AMS39086.1
Pfam:pfam00175 Oxidoreductase NAD-binding domain.
  
 
 0.946
AMS41846.1
Pfam:pfam02570 Precorrin-8X methylmutase.
 
  
 0.919
AMS39211.1
Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
  
  
 0.915
AMS41850.1
Pfam:pfam07845 Protein of unknown function (DUF1636).
 
     0.915
AMS41848.1
Cobalt chelatase; Pfam:pfam02514 CobN/Magnesium Chelatase.
 
   
 0.905
AMS39209.1
Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
  
  
 0.848
cysD
Sulfate adenylyltransferase subunit 2; Pfam:pfam01507 Phosphoadenosine phosphosulfate reductase family.
  
  
 0.834
Your Current Organism:
Aminobacter aminovorans
NCBI taxonomy Id: 83263
Other names: A. aminovorans, ATCC 23314, ATCC 29600, Aminobacter heintzii, CCUG 2081, CIP 106737, Chelatobacter heintzii, DSM 10368, DSM 7048, JCM 7852, KCTC 2477, LMG 2122, LMG:2122, NCCB 26039, NCIB 9039, NCIB:9039, NCIMB 9039, NCTC 10684, Pseudomonas aminovorans, VKM B-2058
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.