Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AMS41868.1methylmalonyl-CoA epimerase; Pfam:pfam13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily. (134 aa)    
Predicted Functional Partners:
AMS39762.1
Pfam:pfam01642 Methylmalonyl-CoA mutase.
 
  
 0.987
AMS39765.1
methylmalonyl-CoA carboxyltransferase; Pfam:pfam01039 Carboxyl transferase domain.
 
 
 0.978
AMS43687.1
methylmalonyl-CoA mutase; Pfam:pfam02310 B12 binding domain.
  
 0.956
AMS39764.1
acetyl-CoA carboxylase; Pfam:pfam02786 Carbamoyl-phosphate synthase L chain, ATP binding domain.
 
 
 0.930
AMS43689.1
Methylmalonyl-CoA mutase, large subunit; Pfam:pfam01642 Methylmalonyl-CoA mutase.
 
  
 0.892
AMS43688.1
Putative enzyme; Pfam:pfam03308 ArgK protein.
 
  
 0.820
AMS41869.1
Pfam:pfam07330 Protein of unknown function (DUF1467).
       0.814
nuoI
NADH-quinone oxidoreductase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
  
 0.689
AMS41866.1
Biotin; Pfam:pfam03099 Biotin/lipoate A/B protein ligase family.
  
    0.650
AMS41867.1
Beta-lactamase; Pfam:pfam00753 Metallo-beta-lactamase superfamily.
       0.625
Your Current Organism:
Aminobacter aminovorans
NCBI taxonomy Id: 83263
Other names: A. aminovorans, ATCC 23314, ATCC 29600, Aminobacter heintzii, CCUG 2081, CIP 106737, Chelatobacter heintzii, DSM 10368, DSM 7048, JCM 7852, KCTC 2477, LMG 2122, LMG:2122, NCCB 26039, NCIB 9039, NCIB:9039, NCIMB 9039, NCTC 10684, Pseudomonas aminovorans, VKM B-2058
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