| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMS38978.1 | AMS39129.1 | AA2016_0035 | AA2016_0187 | Pfam:pfam02773 S-adenosylmethionine synthetase, C-terminal domain; Belongs to the AdoMet synthase family. | Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.952 |
| AMS38978.1 | AMS41936.1 | AA2016_0035 | AA2016_3012 | Pfam:pfam02773 S-adenosylmethionine synthetase, C-terminal domain; Belongs to the AdoMet synthase family. | Pfam:pfam02219 Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.581 |
| AMS38978.1 | AMS41937.1 | AA2016_0035 | AA2016_3013 | Pfam:pfam02773 S-adenosylmethionine synthetase, C-terminal domain; Belongs to the AdoMet synthase family. | Pfam:pfam12225 Methylene-tetrahydrofolate reductase C terminal. | 0.574 |
| AMS38978.1 | metAA | AA2016_0035 | AA2016_1733 | Pfam:pfam02773 S-adenosylmethionine synthetase, C-terminal domain; Belongs to the AdoMet synthase family. | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.677 |
| AMS38978.1 | metH_2 | AA2016_0035 | AA2016_3011 | Pfam:pfam02773 S-adenosylmethionine synthetase, C-terminal domain; Belongs to the AdoMet synthase family. | Methyltetrahydrofolate:corrinoid methyltransferase; Pfam:pfam00809 Pterin binding enzyme. | 0.924 |
| AMS39129.1 | AMS38978.1 | AA2016_0187 | AA2016_0035 | Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Pfam:pfam02773 S-adenosylmethionine synthetase, C-terminal domain; Belongs to the AdoMet synthase family. | 0.952 |
| AMS39129.1 | AMS41934.1 | AA2016_0187 | AA2016_3010 | Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Drug:proton antiporter; Pfam:pfam14574 Domain of unknown function (DUF4445). | 0.509 |
| AMS39129.1 | AMS41936.1 | AA2016_0187 | AA2016_3012 | Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Pfam:pfam02219 Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.897 |
| AMS39129.1 | AMS41937.1 | AA2016_0187 | AA2016_3013 | Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Pfam:pfam12225 Methylene-tetrahydrofolate reductase C terminal. | 0.892 |
| AMS39129.1 | metAA | AA2016_0187 | AA2016_1733 | Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.824 |
| AMS39129.1 | metH_2 | AA2016_0187 | AA2016_3011 | Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methyltetrahydrofolate:corrinoid methyltransferase; Pfam:pfam00809 Pterin binding enzyme. | 0.955 |
| AMS41294.1 | AMS41937.1 | AA2016_2368 | AA2016_3013 | Hypothetical protein. | Pfam:pfam12225 Methylene-tetrahydrofolate reductase C terminal. | 0.589 |
| AMS41934.1 | AMS39129.1 | AA2016_3010 | AA2016_0187 | Drug:proton antiporter; Pfam:pfam14574 Domain of unknown function (DUF4445). | Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.509 |
| AMS41934.1 | AMS41936.1 | AA2016_3010 | AA2016_3012 | Drug:proton antiporter; Pfam:pfam14574 Domain of unknown function (DUF4445). | Pfam:pfam02219 Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.727 |
| AMS41934.1 | AMS41937.1 | AA2016_3010 | AA2016_3013 | Drug:proton antiporter; Pfam:pfam14574 Domain of unknown function (DUF4445). | Pfam:pfam12225 Methylene-tetrahydrofolate reductase C terminal. | 0.777 |
| AMS41934.1 | AMS41938.1 | AA2016_3010 | AA2016_3014 | Drug:proton antiporter; Pfam:pfam14574 Domain of unknown function (DUF4445). | Hypothetical protein; Pfam:pfam13769 Virulence factor. | 0.868 |
| AMS41934.1 | AMS41942.1 | AA2016_3010 | AA2016_3018 | Drug:proton antiporter; Pfam:pfam14574 Domain of unknown function (DUF4445). | Pfam:pfam07796 Protein of unknown function (DUF1638). | 0.850 |
| AMS41934.1 | metH_2 | AA2016_3010 | AA2016_3011 | Drug:proton antiporter; Pfam:pfam14574 Domain of unknown function (DUF4445). | Methyltetrahydrofolate:corrinoid methyltransferase; Pfam:pfam00809 Pterin binding enzyme. | 0.907 |
| AMS41936.1 | AMS38978.1 | AA2016_3012 | AA2016_0035 | Pfam:pfam02219 Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Pfam:pfam02773 S-adenosylmethionine synthetase, C-terminal domain; Belongs to the AdoMet synthase family. | 0.581 |
| AMS41936.1 | AMS39129.1 | AA2016_3012 | AA2016_0187 | Pfam:pfam02219 Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.897 |