Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AMS41937.1Pfam:pfam12225 Methylene-tetrahydrofolate reductase C terminal. (194 aa)    
Predicted Functional Partners:
AMS41936.1
Pfam:pfam02219 Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
     0.985
AMS41938.1
Hypothetical protein; Pfam:pfam13769 Virulence factor.
 
    0.897
metH_2
Methyltetrahydrofolate:corrinoid methyltransferase; Pfam:pfam00809 Pterin binding enzyme.
 
  
 0.848
AMS39129.1
Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
  
 0.841
AMS41934.1
Drug:proton antiporter; Pfam:pfam14574 Domain of unknown function (DUF4445).
 
     0.776
metAA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
  
  
 0.633
AMS41939.1
Hypothetical protein; Pfam:pfam00551 Formyl transferase.
 
   
 0.622
AMS41942.1
Pfam:pfam07796 Protein of unknown function (DUF1638).
 
     0.621
AMS41294.1
Hypothetical protein.
  
     0.589
AMS44071.1
Pfam:pfam06078 Bacterial protein of unknown function (DUF937).
  
     0.572
Your Current Organism:
Aminobacter aminovorans
NCBI taxonomy Id: 83263
Other names: A. aminovorans, ATCC 23314, ATCC 29600, Aminobacter heintzii, CCUG 2081, CIP 106737, Chelatobacter heintzii, DSM 10368, DSM 7048, JCM 7852, KCTC 2477, LMG 2122, LMG:2122, NCCB 26039, NCIB 9039, NCIB:9039, NCIMB 9039, NCTC 10684, Pseudomonas aminovorans, VKM B-2058
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