Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AMS41957.1Methionine synthase; Pfam:pfam02574 Homocysteine S-methyltransferase. (343 aa)    
Predicted Functional Partners:
metH_2
Methyltetrahydrofolate:corrinoid methyltransferase; Pfam:pfam00809 Pterin binding enzyme.
 
 0.998
AMS41936.1
Pfam:pfam02219 Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
 
 0.995
AMS41944.1
5-methyltetrahydrofolate--homocysteine methyltransferase; Pfam:pfam02310 B12 binding domain.
  
 0.986
AMS41708.1
Pfam:pfam02219 Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
 
 
 0.968
AMS43012.1
5,10-methylenetetrahydrofolate reductase.
 
 
 0.959
AMS41572.1
metFprotein; Pfam:pfam02219 Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
 
 
 0.958
AMS39129.1
Homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
 
 
0.953
AMS41964.1
Glycine cleavage system protein T; Pfam:pfam01266 FAD dependent oxidoreductase; Belongs to the GcvT family.
 
 
 0.942
AMS39506.1
Cystathionine beta-lyase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme.
  
 
 0.932
AMS41723.1
Cystathionine gamma-lyase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme.
  
 
 0.932
Your Current Organism:
Aminobacter aminovorans
NCBI taxonomy Id: 83263
Other names: A. aminovorans, ATCC 23314, ATCC 29600, Aminobacter heintzii, CCUG 2081, CIP 106737, Chelatobacter heintzii, DSM 10368, DSM 7048, JCM 7852, KCTC 2477, LMG 2122, LMG:2122, NCCB 26039, NCIB 9039, NCIB:9039, NCIMB 9039, NCTC 10684, Pseudomonas aminovorans, VKM B-2058
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.