Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
kuATP-dependent DNA ligase; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. (290 aa)    
Predicted Functional Partners:
AMS42506.1
Pfam:pfam13298 DNA polymerase Ligase (LigD).
 
  
 0.991
AMS39342.1
Pfam:pfam01068 ATP dependent DNA ligase domain.
 
  
 0.856
AMS41138.1
Hypothetical protein; Pfam:pfam01068 ATP dependent DNA ligase domain.
 
  
 0.856
AMS42502.1
Exodeoxyribonuclease III; Pfam:pfam03372 Endonuclease/Exonuclease/phosphatase family.
 
  
 0.812
AMS42504.1
O-linked GlcNAc transferase; Pfam:pfam13414 TPR repeat.
       0.785
AMS42503.1
Pfam:pfam12695 Alpha/beta hydrolase family.
       0.779
AMS40001.1
Pfam:pfam01028 Eukaryotic DNA topoisomerase I, catalytic core.
 
    0.726
AMS42507.1
Hypothetical protein.
       0.645
AMS44243.1
Pfam:pfam01068 ATP dependent DNA ligase domain.
 
  
 0.586
AMS42671.1
Pfam:pfam01904 Protein of unknown function DUF72.
 
    0.522
Your Current Organism:
Aminobacter aminovorans
NCBI taxonomy Id: 83263
Other names: A. aminovorans, ATCC 23314, ATCC 29600, Aminobacter heintzii, CCUG 2081, CIP 106737, Chelatobacter heintzii, DSM 10368, DSM 7048, JCM 7852, KCTC 2477, LMG 2122, LMG:2122, NCCB 26039, NCIB 9039, NCIB:9039, NCIMB 9039, NCTC 10684, Pseudomonas aminovorans, VKM B-2058
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.