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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
Score
AMS42644.1Serine dehydratase; Pfam:pfam00291 Pyridoxal-phosphate dependent enzyme. (324 aa)    
Predicted Functional Partners:
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
  
 0.611
AMS40133.1
Pfam:pfam00920 Dehydratase family; Belongs to the IlvD/Edd family.
 
 
 0.607
AMS40947.1
Glutamate synthase; Pfam:pfam01645 Conserved region in glutamate synthase.
  
 
 0.596
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 
 
 0.567
AMS43849.1
Pfam:pfam00920 Dehydratase family; Belongs to the IlvD/Edd family.
 
 
 0.564
AMS44274.1
Pfam:pfam00920 Dehydratase family; Belongs to the IlvD/Edd family.
 
 
 0.559
AMS42643.1
Hypothetical protein; Pfam:pfam12847 Methyltransferase domain.
  
 
 0.556
ilvD
Pfam:pfam00920 Dehydratase family; Belongs to the IlvD/Edd family.
 
 
 0.554
dinB-2
DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
  
  
 0.541
AMS43814.1
Pfam:pfam01042 Endoribonuclease L-PSP.
 
 
 0.522
Your Current Organism:
Aminobacter aminovorans
NCBI taxonomy Id: 83263
Other names: A. aminovorans, ATCC 23314, ATCC 29600, Aminobacter heintzii, CCUG 2081, CIP 106737, Chelatobacter heintzii, DSM 10368, DSM 7048, JCM 7852, KCTC 2477, LMG 2122, LMG:2122, NCCB 26039, NCIB 9039, NCIB:9039, NCIMB 9039, NCTC 10684, Pseudomonas aminovorans, VKM B-2058
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