Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AMS43393.1Pfam:pfam00474 Sodium:solute symporter family; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (660 aa)    
Predicted Functional Partners:
AMS43394.1
Membrane protein; Pfam:pfam13937 Domain of unknown function (DUF4212).
 
    0.965
AMS43396.1
DNA polymerase III subunit epsilon; Pfam:pfam03445 Putative nucleotidyltransferase DUF294.
 
  
 0.917
AMS43392.1
Hypothetical protein.
       0.592
AMS43395.1
Hypothetical protein.
       0.543
AMS43391.1
Hypothetical protein.
       0.510
acsA
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 0.508
AMS40464.1
acyl-CoA synthetase; Pfam:pfam00501 AMP-binding enzyme.
  
  
 0.508
AMS40708.1
AMP-dependent synthetase; Pfam:pfam00501 AMP-binding enzyme.
  
  
 0.508
AMS44079.1
acetoacetyl-CoA synthetase; Pfam:pfam00501 AMP-binding enzyme.
  
  
 0.508
AMS42216.1
Inosine-5-monophosphate dehydrogenase; Pfam:pfam00571 CBS domain.
  
  
 0.435
Your Current Organism:
Aminobacter aminovorans
NCBI taxonomy Id: 83263
Other names: A. aminovorans, ATCC 23314, ATCC 29600, Aminobacter heintzii, CCUG 2081, CIP 106737, Chelatobacter heintzii, DSM 10368, DSM 7048, JCM 7852, KCTC 2477, LMG 2122, LMG:2122, NCCB 26039, NCIB 9039, NCIB:9039, NCIMB 9039, NCTC 10684, Pseudomonas aminovorans, VKM B-2058
Server load: medium (54%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.