| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMS38945.1 | AMS40947.1 | AA2016_0002 | AA2016_2017 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Glutamate synthase; Pfam:pfam01645 Conserved region in glutamate synthase. | 0.497 |
| AMS38945.1 | AMS43396.1 | AA2016_0002 | AA2016_4484 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase III subunit epsilon; Pfam:pfam03445 Putative nucleotidyltransferase DUF294. | 0.702 |
| AMS38945.1 | dnaG | AA2016_0002 | AA2016_2577 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.542 |
| AMS38945.1 | guaB | AA2016_0002 | AA2016_4077 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Inosine-5`-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.462 |
| AMS38945.1 | polA | AA2016_0002 | AA2016_0291 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.995 |
| AMS39739.1 | AMS43396.1 | AA2016_0801 | AA2016_4484 | PEP synthetase regulatory protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. | DNA polymerase III subunit epsilon; Pfam:pfam03445 Putative nucleotidyltransferase DUF294. | 0.589 |
| AMS40947.1 | AMS38945.1 | AA2016_2017 | AA2016_0002 | Glutamate synthase; Pfam:pfam01645 Conserved region in glutamate synthase. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.497 |
| AMS40947.1 | AMS43396.1 | AA2016_2017 | AA2016_4484 | Glutamate synthase; Pfam:pfam01645 Conserved region in glutamate synthase. | DNA polymerase III subunit epsilon; Pfam:pfam03445 Putative nucleotidyltransferase DUF294. | 0.639 |
| AMS40947.1 | dnaG | AA2016_2017 | AA2016_2577 | Glutamate synthase; Pfam:pfam01645 Conserved region in glutamate synthase. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.639 |
| AMS40947.1 | guaA | AA2016_2017 | AA2016_5129 | Glutamate synthase; Pfam:pfam01645 Conserved region in glutamate synthase. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.720 |
| AMS40947.1 | guaB | AA2016_2017 | AA2016_4077 | Glutamate synthase; Pfam:pfam01645 Conserved region in glutamate synthase. | Inosine-5`-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.668 |
| AMS40947.1 | polA | AA2016_2017 | AA2016_0291 | Glutamate synthase; Pfam:pfam01645 Conserved region in glutamate synthase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.484 |
| AMS43393.1 | AMS43394.1 | AA2016_4481 | AA2016_4482 | Pfam:pfam00474 Sodium:solute symporter family; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | Membrane protein; Pfam:pfam13937 Domain of unknown function (DUF4212). | 0.965 |
| AMS43393.1 | AMS43396.1 | AA2016_4481 | AA2016_4484 | Pfam:pfam00474 Sodium:solute symporter family; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | DNA polymerase III subunit epsilon; Pfam:pfam03445 Putative nucleotidyltransferase DUF294. | 0.917 |
| AMS43394.1 | AMS43393.1 | AA2016_4482 | AA2016_4481 | Membrane protein; Pfam:pfam13937 Domain of unknown function (DUF4212). | Pfam:pfam00474 Sodium:solute symporter family; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.965 |
| AMS43394.1 | AMS43396.1 | AA2016_4482 | AA2016_4484 | Membrane protein; Pfam:pfam13937 Domain of unknown function (DUF4212). | DNA polymerase III subunit epsilon; Pfam:pfam03445 Putative nucleotidyltransferase DUF294. | 0.803 |
| AMS43396.1 | AMS38945.1 | AA2016_4484 | AA2016_0002 | DNA polymerase III subunit epsilon; Pfam:pfam03445 Putative nucleotidyltransferase DUF294. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.702 |
| AMS43396.1 | AMS39739.1 | AA2016_4484 | AA2016_0801 | DNA polymerase III subunit epsilon; Pfam:pfam03445 Putative nucleotidyltransferase DUF294. | PEP synthetase regulatory protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. | 0.589 |
| AMS43396.1 | AMS40947.1 | AA2016_4484 | AA2016_2017 | DNA polymerase III subunit epsilon; Pfam:pfam03445 Putative nucleotidyltransferase DUF294. | Glutamate synthase; Pfam:pfam01645 Conserved region in glutamate synthase. | 0.639 |
| AMS43396.1 | AMS43393.1 | AA2016_4484 | AA2016_4481 | DNA polymerase III subunit epsilon; Pfam:pfam03445 Putative nucleotidyltransferase DUF294. | Pfam:pfam00474 Sodium:solute symporter family; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.917 |