STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMS43474.12-isopropylmalate synthase; Pfam:pfam00682 HMGL-like; Belongs to the alpha-IPM synthase/homocitrate synthase family. (537 aa)    
Predicted Functional Partners:
leuD
Isopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 
 
 0.987
leuC
Isopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
 
 0.986
ilvD
Pfam:pfam00920 Dehydratase family; Belongs to the IlvD/Edd family.
 
 
 0.969
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 0.969
AMS43625.1
Pfam:pfam01063 Aminotransferase class IV.
  
 0.969
AMS40133.1
Pfam:pfam00920 Dehydratase family; Belongs to the IlvD/Edd family.
 
 
 0.965
AMS41793.1
Pfam:pfam10369 Small subunit of acetolactate synthase.
 
 
 0.962
AMS44274.1
Pfam:pfam00920 Dehydratase family; Belongs to the IlvD/Edd family.
 
 
 0.962
AMS41703.1
Pfam:pfam01063 Aminotransferase class IV.
  
 0.956
AMS41792.1
Acetolactate synthase; Pfam:pfam02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain.
 
 
 0.940
Your Current Organism:
Aminobacter aminovorans
NCBI taxonomy Id: 83263
Other names: A. aminovorans, ATCC 23314, ATCC 29600, Aminobacter heintzii, CCUG 2081, CIP 106737, Chelatobacter heintzii, DSM 10368, DSM 7048, JCM 7852, KCTC 2477, LMG 2122, LMG:2122, NCCB 26039, NCIB 9039, NCIB:9039, NCIMB 9039, NCTC 10684, Pseudomonas aminovorans, VKM B-2058
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