Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
AMS43591.1Pfam:pfam02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (478 aa)    
Predicted Functional Partners:
AMS43592.1
Pfam:pfam00486 Transcriptional regulatory protein, C terminal.
 
 0.969
phoP
Pfam:pfam00486 Transcriptional regulatory protein, C terminal.
 
 
 0.822
glnE
Glutamine-synthetase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transducti [...]
     
 0.820
AMS40554.1
Hypothetical protein; Pfam:pfam02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 
 0.759
AMS43593.1
Serine protease; Pfam:pfam13365 Trypsin-like peptidase domain; Belongs to the peptidase S1C family.
 
  
 0.701
arlR
Pfam:pfam00072 Response regulator receiver domain.
 
 
 0.699
AMS41364.1
Chemotaxis protein CheY; Pfam:pfam00072 Response regulator receiver domain.
 
 
 0.695
phoB_1
Response regulator in two-component regulatory system with PhoR (CreC); Regulation of Pi uptake (OmpR family); Pfam:pfam00072 Response regulator receiver domain.
 
 
 0.691
AMS40756.1
Hypothetical protein; Pfam:pfam00072 Response regulator receiver domain.
 
 
 0.691
AMS40677.1
Hypothetical protein; Pfam:pfam00072 Response regulator receiver domain.
 
 
 0.665
Your Current Organism:
Aminobacter aminovorans
NCBI taxonomy Id: 83263
Other names: A. aminovorans, ATCC 23314, ATCC 29600, Aminobacter heintzii, CCUG 2081, CIP 106737, Chelatobacter heintzii, DSM 10368, DSM 7048, JCM 7852, KCTC 2477, LMG 2122, LMG:2122, NCCB 26039, NCIB 9039, NCIB:9039, NCIMB 9039, NCTC 10684, Pseudomonas aminovorans, VKM B-2058
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