Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AMS43720.1Hypothetical protein; Adenine glycosylase active on G-A mispairs. (374 aa)    
Predicted Functional Partners:
AMS43721.1
Pfam:pfam13419 Haloacid dehalogenase-like hydrolase.
     
 0.850
AMS38945.1
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 
 0.831
AMS39961.1
Exodeoxyribonuclease III; Pfam:pfam03372 Endonuclease/Exonuclease/phosphatase family.
  
 
 0.719
AMS42502.1
Exodeoxyribonuclease III; Pfam:pfam03372 Endonuclease/Exonuclease/phosphatase family.
  
 
 0.715
AMS42253.1
Exodeoxyribonuclease III; Pfam:pfam03372 Endonuclease/Exonuclease/phosphatase family.
  
 
 0.714
AMS39791.1
Metal-dependent hydrolase; Pfam:pfam03372 Endonuclease/Exonuclease/phosphatase family.
    
 0.665
AMS43719.1
Pfam:pfam05258 Protein of unknown function (DUF721).
       0.647
AMS39039.1
Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
 
    0.549
AMS43718.1
Disulfide bond formation protein DsbD; Pfam:pfam13462 Thioredoxin.
     
 0.546
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
  
 0.538
Your Current Organism:
Aminobacter aminovorans
NCBI taxonomy Id: 83263
Other names: A. aminovorans, ATCC 23314, ATCC 29600, Aminobacter heintzii, CCUG 2081, CIP 106737, Chelatobacter heintzii, DSM 10368, DSM 7048, JCM 7852, KCTC 2477, LMG 2122, LMG:2122, NCCB 26039, NCIB 9039, NCIB:9039, NCIMB 9039, NCTC 10684, Pseudomonas aminovorans, VKM B-2058
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