| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMS39952.1 | ubiA | AA2016_1014 | AA2016_4869 | 2-octaprenyl-6-methoxyphenyl hydroxylase; Pfam:pfam01494 FAD binding domain. | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.611 |
| AMS39952.1 | ubiE | AA2016_1014 | AA2016_0120 | 2-octaprenyl-6-methoxyphenyl hydroxylase; Pfam:pfam01494 FAD binding domain. | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.943 |
| AMS39952.1 | ubiG | AA2016_1014 | AA2016_1804 | 2-octaprenyl-6-methoxyphenyl hydroxylase; Pfam:pfam01494 FAD binding domain. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.982 |
| AMS43578.1 | AMS43788.1 | AA2016_4668 | AA2016_4879 | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. | Pfam:pfam00348 Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.547 |
| AMS43578.1 | ubiA | AA2016_4668 | AA2016_4869 | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.648 |
| AMS43578.1 | ubiG | AA2016_4668 | AA2016_1804 | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.486 |
| AMS43788.1 | AMS43578.1 | AA2016_4879 | AA2016_4668 | Pfam:pfam00348 Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. | 0.547 |
| AMS43788.1 | ubiA | AA2016_4879 | AA2016_4869 | Pfam:pfam00348 Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.919 |
| AMS43788.1 | ubiE | AA2016_4879 | AA2016_0120 | Pfam:pfam00348 Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.657 |
| AMS43926.1 | ubiA | AA2016_5018 | AA2016_4869 | 3-octaprenyl-4hydroxybenzoate decarboxylase; Pfam:pfam01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Belongs to the UbiD family. | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.946 |
| AMS43926.1 | ubiX | AA2016_5018 | AA2016_1198 | 3-octaprenyl-4hydroxybenzoate decarboxylase; Pfam:pfam01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Belongs to the UbiD family. | Aromatic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.987 |
| AMS43926.1 | ubiX-2 | AA2016_5018 | AA2016_4959 | 3-octaprenyl-4hydroxybenzoate decarboxylase; Pfam:pfam01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Belongs to the UbiD family. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.987 |
| AMS43926.1 | ubiX-3 | AA2016_5018 | AA2016_5017 | 3-octaprenyl-4hydroxybenzoate decarboxylase; Pfam:pfam01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Belongs to the UbiD family. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.997 |
| purD | ubiA | AA2016_4868 | AA2016_4869 | Phosphoribosylamine--glycine ligase; Pfam:pfam01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Belongs to the GARS family. | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.693 |
| ubiA | AMS39952.1 | AA2016_4869 | AA2016_1014 | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 2-octaprenyl-6-methoxyphenyl hydroxylase; Pfam:pfam01494 FAD binding domain. | 0.611 |
| ubiA | AMS43578.1 | AA2016_4869 | AA2016_4668 | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. | 0.648 |
| ubiA | AMS43788.1 | AA2016_4869 | AA2016_4879 | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | Pfam:pfam00348 Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.919 |
| ubiA | AMS43926.1 | AA2016_4869 | AA2016_5018 | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 3-octaprenyl-4hydroxybenzoate decarboxylase; Pfam:pfam01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Belongs to the UbiD family. | 0.946 |
| ubiA | purD | AA2016_4869 | AA2016_4868 | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | Phosphoribosylamine--glycine ligase; Pfam:pfam01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Belongs to the GARS family. | 0.693 |
| ubiA | ubiE | AA2016_4869 | AA2016_0120 | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.670 |