| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMS43780.1 | AMS43781.1 | AA2016_4871 | AA2016_4872 | 2-hydroxyacid dehydrogenase; Pfam:pfam02913 FAD linked oxidases, C-terminal domain. | Translation factor Sua5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.752 |
| AMS43780.1 | AMS43782.1 | AA2016_4871 | AA2016_4873 | 2-hydroxyacid dehydrogenase; Pfam:pfam02913 FAD linked oxidases, C-terminal domain. | Hypothetical protein. | 0.490 |
| AMS43781.1 | AMS43780.1 | AA2016_4872 | AA2016_4871 | Translation factor Sua5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 2-hydroxyacid dehydrogenase; Pfam:pfam02913 FAD linked oxidases, C-terminal domain. | 0.752 |
| AMS43781.1 | AMS43782.1 | AA2016_4872 | AA2016_4873 | Translation factor Sua5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Hypothetical protein. | 0.512 |
| AMS43781.1 | glmS | AA2016_4872 | AA2016_3706 | Translation factor Sua5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.473 |
| AMS43781.1 | glyA | AA2016_4872 | AA2016_2628 | Translation factor Sua5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.472 |
| AMS43781.1 | polA | AA2016_4872 | AA2016_0291 | Translation factor Sua5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.500 |
| AMS43781.1 | prmC | AA2016_4872 | AA2016_1808 | Translation factor Sua5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Hypothetical protein; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.702 |
| AMS43781.1 | rho | AA2016_4872 | AA2016_0804 | Translation factor Sua5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.477 |
| AMS43781.1 | rpoZ | AA2016_4872 | AA2016_4633 | Translation factor Sua5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.469 |
| AMS43781.1 | rsmA | AA2016_4872 | AA2016_4529 | Translation factor Sua5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 16S rRNA methyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.535 |
| AMS43781.1 | tsaD | AA2016_4872 | AA2016_1033 | Translation factor Sua5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Protein kinase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.484 |
| AMS43782.1 | AMS43780.1 | AA2016_4873 | AA2016_4871 | Hypothetical protein. | 2-hydroxyacid dehydrogenase; Pfam:pfam02913 FAD linked oxidases, C-terminal domain. | 0.490 |
| AMS43782.1 | AMS43781.1 | AA2016_4873 | AA2016_4872 | Hypothetical protein. | Translation factor Sua5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.512 |
| glmS | AMS43781.1 | AA2016_3706 | AA2016_4872 | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Translation factor Sua5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.473 |
| glmS | polA | AA2016_3706 | AA2016_0291 | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.476 |
| glyA | AMS43781.1 | AA2016_2628 | AA2016_4872 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Translation factor Sua5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.472 |
| glyA | polA | AA2016_2628 | AA2016_0291 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.520 |
| polA | AMS43781.1 | AA2016_0291 | AA2016_4872 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Translation factor Sua5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.500 |
| polA | glmS | AA2016_0291 | AA2016_3706 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.476 |