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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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AMS43989.1Threonine synthase-like protein; Pfam:pfam00291 Pyridoxal-phosphate dependent enzyme. (423 aa)    
Predicted Functional Partners:
AMS40316.1
Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.
   
 0.944
AMS41455.1
Serine dehydratase; Pfam:pfam00291 Pyridoxal-phosphate dependent enzyme.
  
 
0.931
ilvA
Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
  
 
 0.931
AMS43637.1
Pyridoxal-5-phosphate-dependent protein subunit beta; Pfam:pfam00291 Pyridoxal-phosphate dependent enzyme.
  
 
 0.931
AMS40946.1
Hypothetical protein; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.
   
 0.928
thrB
Homoserine kinase; Pfam:pfam01636 Phosphotransferase enzyme family; Belongs to the pseudomonas-type ThrB family.
    
 0.917
AMS39548.1
L-threonine 3-dehydrogenase; Pfam:pfam08240 Alcohol dehydrogenase GroES-like domain.
   
 
 0.906
tdh
L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family.
   
 
 0.906
pdxA
4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
    
  0.903
AMS43730.1
Pfam:pfam14821 Threonine synthase N terminus.
     
  0.900
Your Current Organism:
Aminobacter aminovorans
NCBI taxonomy Id: 83263
Other names: A. aminovorans, ATCC 23314, ATCC 29600, Aminobacter heintzii, CCUG 2081, CIP 106737, Chelatobacter heintzii, DSM 10368, DSM 7048, JCM 7852, KCTC 2477, LMG 2122, LMG:2122, NCCB 26039, NCIB 9039, NCIB:9039, NCIMB 9039, NCTC 10684, Pseudomonas aminovorans, VKM B-2058
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