| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Rv2509 | aftB | Rv2509 | Rv3805c | Rv2509, (MTCY07A7.15), len: 268 aa. Probable ala-rich oxidoreductase, short-chain dehydrogenase/reductase, equivalent to O07709|MLCL383.36c|ML0429 dehydrogenase (putative oxidoreductase) from Mycobacterium leprae (268 aa), FASTA scores: opt: 1509, E(): 2.6e-84, (88.75% identity in 267 aa overlap). Also highly similar to others e.g. O86553|SC1F2.16c putative dehydrogenase from Streptomyces coelicolor (276 aa), FASTA scores: opt: 492, E(): 9.5e-23,(38.15% identity in 262 aa overlap); Q9I5R3|PA0658 probable short-chain dehydrogenase from Pseudomonas aeruginosa (266 aa), FASTA scores: opt: [...] | Possible arabinofuranosyltransferase AftB; Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the mycobacterial cell wall. Catalyzes the transfer of arabinofuranosyl (Araf) residues from the sugar donor decaprenyl-phospho-arabinose (DPA) to the arabinan domain to form terminal beta-(1->2)-linked Araf residues, which marks the end point for AG arabinan biosynthesis before decoration with mycolic acids. | 0.477 |
| Rv2509 | fbpA | Rv2509 | Rv3804c | Rv2509, (MTCY07A7.15), len: 268 aa. Probable ala-rich oxidoreductase, short-chain dehydrogenase/reductase, equivalent to O07709|MLCL383.36c|ML0429 dehydrogenase (putative oxidoreductase) from Mycobacterium leprae (268 aa), FASTA scores: opt: 1509, E(): 2.6e-84, (88.75% identity in 267 aa overlap). Also highly similar to others e.g. O86553|SC1F2.16c putative dehydrogenase from Streptomyces coelicolor (276 aa), FASTA scores: opt: 492, E(): 9.5e-23,(38.15% identity in 262 aa overlap); Q9I5R3|PA0658 probable short-chain dehydrogenase from Pseudomonas aeruginosa (266 aa), FASTA scores: opt: [...] | Diacylglycerol acyltransferase/mycolyltransferase Ag85A; The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria for fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M.tuberculosis to murine alveolar macrophages (AMs). They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan, and through the synthesis of alpha,alpha- trehalose dimycolate (TDM, cord factor). They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-treh [...] | 0.915 |
| Rv2509 | fbpB | Rv2509 | Rv1886c | Rv2509, (MTCY07A7.15), len: 268 aa. Probable ala-rich oxidoreductase, short-chain dehydrogenase/reductase, equivalent to O07709|MLCL383.36c|ML0429 dehydrogenase (putative oxidoreductase) from Mycobacterium leprae (268 aa), FASTA scores: opt: 1509, E(): 2.6e-84, (88.75% identity in 267 aa overlap). Also highly similar to others e.g. O86553|SC1F2.16c putative dehydrogenase from Streptomyces coelicolor (276 aa), FASTA scores: opt: 492, E(): 9.5e-23,(38.15% identity in 262 aa overlap); Q9I5R3|PA0658 probable short-chain dehydrogenase from Pseudomonas aeruginosa (266 aa), FASTA scores: opt: [...] | Diacylglycerol acyltransferase/mycolyltransferase Ag85B; The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria for fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M.tuberculosis to murine alveolar macrophages (AMs). They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan and through the synthesis of alpha,alpha- trehalose dimycolate (TDM, cord factor). They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-treha [...] | 0.918 |
| Rv2509 | fbpC | Rv2509 | Rv0129c | Rv2509, (MTCY07A7.15), len: 268 aa. Probable ala-rich oxidoreductase, short-chain dehydrogenase/reductase, equivalent to O07709|MLCL383.36c|ML0429 dehydrogenase (putative oxidoreductase) from Mycobacterium leprae (268 aa), FASTA scores: opt: 1509, E(): 2.6e-84, (88.75% identity in 267 aa overlap). Also highly similar to others e.g. O86553|SC1F2.16c putative dehydrogenase from Streptomyces coelicolor (276 aa), FASTA scores: opt: 492, E(): 9.5e-23,(38.15% identity in 262 aa overlap); Q9I5R3|PA0658 probable short-chain dehydrogenase from Pseudomonas aeruginosa (266 aa), FASTA scores: opt: [...] | Diacylglycerol acyltransferase/mycolyltransferase Ag85C; The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria to fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M.tuberculosis to murine alveolar macrophages (AMs). They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan and through the synthesis of alpha,alpha- trehalose dimycolate (TDM, cord factor). They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-trehal [...] | 0.929 |
| Rv2509 | pks13 | Rv2509 | Rv3800c | Rv2509, (MTCY07A7.15), len: 268 aa. Probable ala-rich oxidoreductase, short-chain dehydrogenase/reductase, equivalent to O07709|MLCL383.36c|ML0429 dehydrogenase (putative oxidoreductase) from Mycobacterium leprae (268 aa), FASTA scores: opt: 1509, E(): 2.6e-84, (88.75% identity in 267 aa overlap). Also highly similar to others e.g. O86553|SC1F2.16c putative dehydrogenase from Streptomyces coelicolor (276 aa), FASTA scores: opt: 492, E(): 9.5e-23,(38.15% identity in 262 aa overlap); Q9I5R3|PA0658 probable short-chain dehydrogenase from Pseudomonas aeruginosa (266 aa), FASTA scores: opt: [...] | Polyketide synthase Pks13; Rv3800c, (MTV026.05c), len: 1733 aa. Probable pks13,polyketide synthase, equivalent to Q9CDB1|PKS13|ML0101 polyketide synthase from Mycobacterium leprae (1784 aa),FASTA scores: opt: 7454, E(): 0, (83.6% identity in 1748 aa overlap); and similar to Q9Z5K6|ML2357|MLCB12.02c putative polyketide synthase from Mycobacterium leprae (1871 aa),FASTA scores: opt: 1682, E(): 1.2e-85, (38.3% identity in 1096 aa overlap). Also similar in part to many e.g. Q9ADL6|SORA soraphen polyketide synthase a from Polyangium cellulosum (6315 aa) FASTA scores: opt: 1422, E(): 1e-70,( [...] | 0.978 |
| Rv3267 | aftB | Rv3267 | Rv3805c | Rv3267, (MTCY71.07), len: 498 aa. Conserved protein,CPSA-related protein, equivalent to Q9CCK9|ML0750 hypothetical protein from Mycobacterium leprae (489 aa),FASTA scores: opt: 2523, E(): 5e-138, (78.9% identity in 498 aa overlap); and Q50160|CPSA (hypothetical protein CPSA) from Mycobacterium leprae (516 aa), FASTA scores: opt: 868, E(): 1.2e-42, (34.7% identity in 507 aa overlap). Also similar to O06347|CPSA|Rv3484|MTCY13E12.37 CPSA from Mycobacterium tuberculosis (512 aa), FASTA scores: opt: 928, E(): 4.2e-46, (37.35% identity in 498 aa overlap); and O53834|Rv0822c|MTV043.14c hypoth [...] | Possible arabinofuranosyltransferase AftB; Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the mycobacterial cell wall. Catalyzes the transfer of arabinofuranosyl (Araf) residues from the sugar donor decaprenyl-phospho-arabinose (DPA) to the arabinan domain to form terminal beta-(1->2)-linked Araf residues, which marks the end point for AG arabinan biosynthesis before decoration with mycolic acids. | 0.960 |
| Rv3267 | fbpA | Rv3267 | Rv3804c | Rv3267, (MTCY71.07), len: 498 aa. Conserved protein,CPSA-related protein, equivalent to Q9CCK9|ML0750 hypothetical protein from Mycobacterium leprae (489 aa),FASTA scores: opt: 2523, E(): 5e-138, (78.9% identity in 498 aa overlap); and Q50160|CPSA (hypothetical protein CPSA) from Mycobacterium leprae (516 aa), FASTA scores: opt: 868, E(): 1.2e-42, (34.7% identity in 507 aa overlap). Also similar to O06347|CPSA|Rv3484|MTCY13E12.37 CPSA from Mycobacterium tuberculosis (512 aa), FASTA scores: opt: 928, E(): 4.2e-46, (37.35% identity in 498 aa overlap); and O53834|Rv0822c|MTV043.14c hypoth [...] | Diacylglycerol acyltransferase/mycolyltransferase Ag85A; The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria for fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M.tuberculosis to murine alveolar macrophages (AMs). They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan, and through the synthesis of alpha,alpha- trehalose dimycolate (TDM, cord factor). They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-treh [...] | 0.912 |
| Rv3267 | fbpB | Rv3267 | Rv1886c | Rv3267, (MTCY71.07), len: 498 aa. Conserved protein,CPSA-related protein, equivalent to Q9CCK9|ML0750 hypothetical protein from Mycobacterium leprae (489 aa),FASTA scores: opt: 2523, E(): 5e-138, (78.9% identity in 498 aa overlap); and Q50160|CPSA (hypothetical protein CPSA) from Mycobacterium leprae (516 aa), FASTA scores: opt: 868, E(): 1.2e-42, (34.7% identity in 507 aa overlap). Also similar to O06347|CPSA|Rv3484|MTCY13E12.37 CPSA from Mycobacterium tuberculosis (512 aa), FASTA scores: opt: 928, E(): 4.2e-46, (37.35% identity in 498 aa overlap); and O53834|Rv0822c|MTV043.14c hypoth [...] | Diacylglycerol acyltransferase/mycolyltransferase Ag85B; The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria for fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M.tuberculosis to murine alveolar macrophages (AMs). They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan and through the synthesis of alpha,alpha- trehalose dimycolate (TDM, cord factor). They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-treha [...] | 0.913 |
| Rv3267 | fbpC | Rv3267 | Rv0129c | Rv3267, (MTCY71.07), len: 498 aa. Conserved protein,CPSA-related protein, equivalent to Q9CCK9|ML0750 hypothetical protein from Mycobacterium leprae (489 aa),FASTA scores: opt: 2523, E(): 5e-138, (78.9% identity in 498 aa overlap); and Q50160|CPSA (hypothetical protein CPSA) from Mycobacterium leprae (516 aa), FASTA scores: opt: 868, E(): 1.2e-42, (34.7% identity in 507 aa overlap). Also similar to O06347|CPSA|Rv3484|MTCY13E12.37 CPSA from Mycobacterium tuberculosis (512 aa), FASTA scores: opt: 928, E(): 4.2e-46, (37.35% identity in 498 aa overlap); and O53834|Rv0822c|MTV043.14c hypoth [...] | Diacylglycerol acyltransferase/mycolyltransferase Ag85C; The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria to fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M.tuberculosis to murine alveolar macrophages (AMs). They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan and through the synthesis of alpha,alpha- trehalose dimycolate (TDM, cord factor). They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-trehal [...] | 0.920 |
| aftB | Rv2509 | Rv3805c | Rv2509 | Possible arabinofuranosyltransferase AftB; Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the mycobacterial cell wall. Catalyzes the transfer of arabinofuranosyl (Araf) residues from the sugar donor decaprenyl-phospho-arabinose (DPA) to the arabinan domain to form terminal beta-(1->2)-linked Araf residues, which marks the end point for AG arabinan biosynthesis before decoration with mycolic acids. | Rv2509, (MTCY07A7.15), len: 268 aa. Probable ala-rich oxidoreductase, short-chain dehydrogenase/reductase, equivalent to O07709|MLCL383.36c|ML0429 dehydrogenase (putative oxidoreductase) from Mycobacterium leprae (268 aa), FASTA scores: opt: 1509, E(): 2.6e-84, (88.75% identity in 267 aa overlap). Also highly similar to others e.g. O86553|SC1F2.16c putative dehydrogenase from Streptomyces coelicolor (276 aa), FASTA scores: opt: 492, E(): 9.5e-23,(38.15% identity in 262 aa overlap); Q9I5R3|PA0658 probable short-chain dehydrogenase from Pseudomonas aeruginosa (266 aa), FASTA scores: opt: [...] | 0.477 |
| aftB | Rv3267 | Rv3805c | Rv3267 | Possible arabinofuranosyltransferase AftB; Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the mycobacterial cell wall. Catalyzes the transfer of arabinofuranosyl (Araf) residues from the sugar donor decaprenyl-phospho-arabinose (DPA) to the arabinan domain to form terminal beta-(1->2)-linked Araf residues, which marks the end point for AG arabinan biosynthesis before decoration with mycolic acids. | Rv3267, (MTCY71.07), len: 498 aa. Conserved protein,CPSA-related protein, equivalent to Q9CCK9|ML0750 hypothetical protein from Mycobacterium leprae (489 aa),FASTA scores: opt: 2523, E(): 5e-138, (78.9% identity in 498 aa overlap); and Q50160|CPSA (hypothetical protein CPSA) from Mycobacterium leprae (516 aa), FASTA scores: opt: 868, E(): 1.2e-42, (34.7% identity in 507 aa overlap). Also similar to O06347|CPSA|Rv3484|MTCY13E12.37 CPSA from Mycobacterium tuberculosis (512 aa), FASTA scores: opt: 928, E(): 4.2e-46, (37.35% identity in 498 aa overlap); and O53834|Rv0822c|MTV043.14c hypoth [...] | 0.960 |
| aftB | fbpA | Rv3805c | Rv3804c | Possible arabinofuranosyltransferase AftB; Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the mycobacterial cell wall. Catalyzes the transfer of arabinofuranosyl (Araf) residues from the sugar donor decaprenyl-phospho-arabinose (DPA) to the arabinan domain to form terminal beta-(1->2)-linked Araf residues, which marks the end point for AG arabinan biosynthesis before decoration with mycolic acids. | Diacylglycerol acyltransferase/mycolyltransferase Ag85A; The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria for fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M.tuberculosis to murine alveolar macrophages (AMs). They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan, and through the synthesis of alpha,alpha- trehalose dimycolate (TDM, cord factor). They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-treh [...] | 0.867 |
| aftB | fbpB | Rv3805c | Rv1886c | Possible arabinofuranosyltransferase AftB; Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the mycobacterial cell wall. Catalyzes the transfer of arabinofuranosyl (Araf) residues from the sugar donor decaprenyl-phospho-arabinose (DPA) to the arabinan domain to form terminal beta-(1->2)-linked Araf residues, which marks the end point for AG arabinan biosynthesis before decoration with mycolic acids. | Diacylglycerol acyltransferase/mycolyltransferase Ag85B; The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria for fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M.tuberculosis to murine alveolar macrophages (AMs). They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan and through the synthesis of alpha,alpha- trehalose dimycolate (TDM, cord factor). They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-treha [...] | 0.790 |
| aftB | fbpC | Rv3805c | Rv0129c | Possible arabinofuranosyltransferase AftB; Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the mycobacterial cell wall. Catalyzes the transfer of arabinofuranosyl (Araf) residues from the sugar donor decaprenyl-phospho-arabinose (DPA) to the arabinan domain to form terminal beta-(1->2)-linked Araf residues, which marks the end point for AG arabinan biosynthesis before decoration with mycolic acids. | Diacylglycerol acyltransferase/mycolyltransferase Ag85C; The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria to fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M.tuberculosis to murine alveolar macrophages (AMs). They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan and through the synthesis of alpha,alpha- trehalose dimycolate (TDM, cord factor). They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-trehal [...] | 0.824 |
| aftB | pirG | Rv3805c | Rv3810 | Possible arabinofuranosyltransferase AftB; Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the mycobacterial cell wall. Catalyzes the transfer of arabinofuranosyl (Araf) residues from the sugar donor decaprenyl-phospho-arabinose (DPA) to the arabinan domain to form terminal beta-(1->2)-linked Araf residues, which marks the end point for AG arabinan biosynthesis before decoration with mycolic acids. | Exported repetitive protein precursor PirG (cell surface protein) (EXP53); Surface-exposed protein required for multiplication and intracellular growth; To M.leprae 28 kDa antigen. | 0.686 |
| aftB | pks13 | Rv3805c | Rv3800c | Possible arabinofuranosyltransferase AftB; Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the mycobacterial cell wall. Catalyzes the transfer of arabinofuranosyl (Araf) residues from the sugar donor decaprenyl-phospho-arabinose (DPA) to the arabinan domain to form terminal beta-(1->2)-linked Araf residues, which marks the end point for AG arabinan biosynthesis before decoration with mycolic acids. | Polyketide synthase Pks13; Rv3800c, (MTV026.05c), len: 1733 aa. Probable pks13,polyketide synthase, equivalent to Q9CDB1|PKS13|ML0101 polyketide synthase from Mycobacterium leprae (1784 aa),FASTA scores: opt: 7454, E(): 0, (83.6% identity in 1748 aa overlap); and similar to Q9Z5K6|ML2357|MLCB12.02c putative polyketide synthase from Mycobacterium leprae (1871 aa),FASTA scores: opt: 1682, E(): 1.2e-85, (38.3% identity in 1096 aa overlap). Also similar in part to many e.g. Q9ADL6|SORA soraphen polyketide synthase a from Polyangium cellulosum (6315 aa) FASTA scores: opt: 1422, E(): 1e-70,( [...] | 0.712 |
| cut3 | fbpA | Rv3451 | Rv3804c | Rv3451, (MTCY13E12.04), len: 262 aa. Probable cut3,cutinase precursor, similar to others e.g. Q9KK87 from Mycobacterium avium (220 aa), FASTA scores: opt: 540, E(): 3.5e-24, (43.4% identity in 219 aa overlap); Q00298|CUTI_BOTCI|CUTA from Botrytis cinerea (Botryotinia fuckeliana) (202 aa), FASTA scores: opt: 214, E(): 2e-05,(31.45% identity in 210 aa overlap); Q9Y7G8 from Pyrenopeziza brassicae (203 aa), FASTA scores: opt: 203,E(): 8.5e-05, (31.05% identity in 190 aa overlap); P29292|CUTI_ASCRA from Ascochyta rabiei (223 aa), FASTA scores: opt: 155, E(): 0.054, (31.65% identity in 120 a [...] | Diacylglycerol acyltransferase/mycolyltransferase Ag85A; The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria for fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M.tuberculosis to murine alveolar macrophages (AMs). They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan, and through the synthesis of alpha,alpha- trehalose dimycolate (TDM, cord factor). They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-treh [...] | 0.915 |
| cut3 | fbpB | Rv3451 | Rv1886c | Rv3451, (MTCY13E12.04), len: 262 aa. Probable cut3,cutinase precursor, similar to others e.g. Q9KK87 from Mycobacterium avium (220 aa), FASTA scores: opt: 540, E(): 3.5e-24, (43.4% identity in 219 aa overlap); Q00298|CUTI_BOTCI|CUTA from Botrytis cinerea (Botryotinia fuckeliana) (202 aa), FASTA scores: opt: 214, E(): 2e-05,(31.45% identity in 210 aa overlap); Q9Y7G8 from Pyrenopeziza brassicae (203 aa), FASTA scores: opt: 203,E(): 8.5e-05, (31.05% identity in 190 aa overlap); P29292|CUTI_ASCRA from Ascochyta rabiei (223 aa), FASTA scores: opt: 155, E(): 0.054, (31.65% identity in 120 a [...] | Diacylglycerol acyltransferase/mycolyltransferase Ag85B; The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria for fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M.tuberculosis to murine alveolar macrophages (AMs). They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan and through the synthesis of alpha,alpha- trehalose dimycolate (TDM, cord factor). They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-treha [...] | 0.900 |
| cut3 | fbpC | Rv3451 | Rv0129c | Rv3451, (MTCY13E12.04), len: 262 aa. Probable cut3,cutinase precursor, similar to others e.g. Q9KK87 from Mycobacterium avium (220 aa), FASTA scores: opt: 540, E(): 3.5e-24, (43.4% identity in 219 aa overlap); Q00298|CUTI_BOTCI|CUTA from Botrytis cinerea (Botryotinia fuckeliana) (202 aa), FASTA scores: opt: 214, E(): 2e-05,(31.45% identity in 210 aa overlap); Q9Y7G8 from Pyrenopeziza brassicae (203 aa), FASTA scores: opt: 203,E(): 8.5e-05, (31.05% identity in 190 aa overlap); P29292|CUTI_ASCRA from Ascochyta rabiei (223 aa), FASTA scores: opt: 155, E(): 0.054, (31.65% identity in 120 a [...] | Diacylglycerol acyltransferase/mycolyltransferase Ag85C; The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria to fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M.tuberculosis to murine alveolar macrophages (AMs). They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan and through the synthesis of alpha,alpha- trehalose dimycolate (TDM, cord factor). They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-trehal [...] | 0.938 |
| dagK | fbpA | Rv2252 | Rv3804c | Diacylglycerol kinase; Catalyzes the phosphorylation of diacylglycerol (DAG) into phosphatidic acid. Is involved in the biosynthesis of phosphatidylinositol mannosides (PIMs), probably via a role in the biosynthesis of phosphatidylinositol (PI), a PIM precursor, which is derived from phosphatidic acid (By similarity); Belongs to the diacylglycerol/lipid kinase family. | Diacylglycerol acyltransferase/mycolyltransferase Ag85A; The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria for fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M.tuberculosis to murine alveolar macrophages (AMs). They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan, and through the synthesis of alpha,alpha- trehalose dimycolate (TDM, cord factor). They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-treh [...] | 0.900 |
