Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Rv1268c | Rv1269c | Rv1268c | Rv1269c | Hypothetical protein; Rv1268c, (MTCY50.14), len: 232 aa. Hypothetical unknown protein, probably secreted protein : contains possible signal peptide sequence (score 7.9 at residue 28). Predicted to be an outer membrane protein (See Song et al.,2008). | Rv1269c, (MTCY50.13), len: 124 aa. Conserved probable exported protein with putative N-terminal signal sequence. Similar to Mycobacterium tuberculosis protein Rv1813c|Y0DU_MYCTU|Q50620 hypothetical protein cy1a11.30 (137 aa), FASTA scores: E(): 9e-21, (41.6% identity in 137 aa overlap). | 0.491 |
| Rv1268c | lprA | Rv1268c | Rv1270c | Hypothetical protein; Rv1268c, (MTCY50.14), len: 232 aa. Hypothetical unknown protein, probably secreted protein : contains possible signal peptide sequence (score 7.9 at residue 28). Predicted to be an outer membrane protein (See Song et al.,2008). | Possible lipoprotein LprA; Constitutes a host TLR2 agonist (toll-like receptor), shown experimentally for human and mouse. In host cells full-length (acylated) protein acts as a TLR2 agonist, inducing human and murine macrophages to produce cytokines, inducing murine dendritic cell maturation and cytokine production and inhibiting antibody processing in murine macrophages. Binds diacylated phosphatidyl-myo-inositol mannosides (PIMs). Does not induce murine macrophage apoptosis or necrosis. Non- acylated protein does not act as a TLR2 agonist. Requires only host TLR2 as receptors to eli [...] | 0.402 |
| Rv1269c | Rv1268c | Rv1269c | Rv1268c | Rv1269c, (MTCY50.13), len: 124 aa. Conserved probable exported protein with putative N-terminal signal sequence. Similar to Mycobacterium tuberculosis protein Rv1813c|Y0DU_MYCTU|Q50620 hypothetical protein cy1a11.30 (137 aa), FASTA scores: E(): 9e-21, (41.6% identity in 137 aa overlap). | Hypothetical protein; Rv1268c, (MTCY50.14), len: 232 aa. Hypothetical unknown protein, probably secreted protein : contains possible signal peptide sequence (score 7.9 at residue 28). Predicted to be an outer membrane protein (See Song et al.,2008). | 0.491 |
| Rv1269c | Rv1747 | Rv1269c | Rv1747 | Rv1269c, (MTCY50.13), len: 124 aa. Conserved probable exported protein with putative N-terminal signal sequence. Similar to Mycobacterium tuberculosis protein Rv1813c|Y0DU_MYCTU|Q50620 hypothetical protein cy1a11.30 (137 aa), FASTA scores: E(): 9e-21, (41.6% identity in 137 aa overlap). | Probable conserved transmembrane ATP-binding protein ABC transporter; Involved in the translocation of an unknown substrate across the membrane. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation. Required for virulence; In the C-terminal section; belongs to the ABC-2 integral membrane protein family. | 0.457 |
| Rv1269c | Rv3005c | Rv1269c | Rv3005c | Rv1269c, (MTCY50.13), len: 124 aa. Conserved probable exported protein with putative N-terminal signal sequence. Similar to Mycobacterium tuberculosis protein Rv1813c|Y0DU_MYCTU|Q50620 hypothetical protein cy1a11.30 (137 aa), FASTA scores: E(): 9e-21, (41.6% identity in 137 aa overlap). | Rv3005c, (MTV012.19c), len: 279 aa. Conserved hypothetical protein, equivalent to O33110|MLCB637.18|ML1698 hypothetical 29.5 KDA protein from Mycobacterium leprae (277 aa), FASTA scores: opt: 1245,E(): 1.2e-65, (70.5% identity in 278 aa overlap). Also similar, but longer approximately 100 aa in N-terminus, to other hypothetical proteins, few membrane proteins, e.g. Q9RKN9|SCC75A.35 putative membrane protein from Streptomyces coelicolor (180 aa), FASTA scores: opt: 326,E(): 3.9e-12, (44.2% identity in 138 aa overlap); P96694|YDFP|AB001488 hypothetical protein from Bacillus subtilis (129 [...] | 0.651 |
| Rv1269c | lprA | Rv1269c | Rv1270c | Rv1269c, (MTCY50.13), len: 124 aa. Conserved probable exported protein with putative N-terminal signal sequence. Similar to Mycobacterium tuberculosis protein Rv1813c|Y0DU_MYCTU|Q50620 hypothetical protein cy1a11.30 (137 aa), FASTA scores: E(): 9e-21, (41.6% identity in 137 aa overlap). | Possible lipoprotein LprA; Constitutes a host TLR2 agonist (toll-like receptor), shown experimentally for human and mouse. In host cells full-length (acylated) protein acts as a TLR2 agonist, inducing human and murine macrophages to produce cytokines, inducing murine dendritic cell maturation and cytokine production and inhibiting antibody processing in murine macrophages. Binds diacylated phosphatidyl-myo-inositol mannosides (PIMs). Does not induce murine macrophage apoptosis or necrosis. Non- acylated protein does not act as a TLR2 agonist. Requires only host TLR2 as receptors to eli [...] | 0.668 |
| Rv1269c | mmpL4 | Rv1269c | Rv0450c | Rv1269c, (MTCY50.13), len: 124 aa. Conserved probable exported protein with putative N-terminal signal sequence. Similar to Mycobacterium tuberculosis protein Rv1813c|Y0DU_MYCTU|Q50620 hypothetical protein cy1a11.30 (137 aa), FASTA scores: E(): 9e-21, (41.6% identity in 137 aa overlap). | Probable conserved transmembrane transport protein MmpL4; Part of an export system, which is required for biosynthesis and secretion of siderophores. Essential for normal replication during the active-growth phase of the murine tuberculosis model. | 0.571 |
| Rv1269c | sseA | Rv1269c | Rv3283 | Rv1269c, (MTCY50.13), len: 124 aa. Conserved probable exported protein with putative N-terminal signal sequence. Similar to Mycobacterium tuberculosis protein Rv1813c|Y0DU_MYCTU|Q50620 hypothetical protein cy1a11.30 (137 aa), FASTA scores: E(): 9e-21, (41.6% identity in 137 aa overlap). | Rv3283, (MTCY71.23), len: 297 aa. Probable sseA,thiosulfate sulfurtransferase, equivalent P46700|THT2_MYCLE|SSEA|ML0728|B1308_C1_127 putative thiosulfate sulfurtransferase SSEA from Mycobacterium leprae (296 aa), FASTA scores: opt: 1742, E(): 5.5e-108,(83.45% identity in 296 aa overlap). Also highly similar to others e.g. Q9RXT9|DR0217 from Deinococcus radiodurans (286 aa), FASTA scores: opt: 1057, E(): 1.2e-62, (53.86% identity in 273 aa overlap); P16385|THTR_SACER|CYSA from Saccharopolyspora erythraea (Streptomyces erythraeus) (281 aa), FASTA scores: opt: 1006, E(): 2.7e-59, (51.25% [...] | 0.811 |
| Rv1747 | Rv1269c | Rv1747 | Rv1269c | Probable conserved transmembrane ATP-binding protein ABC transporter; Involved in the translocation of an unknown substrate across the membrane. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation. Required for virulence; In the C-terminal section; belongs to the ABC-2 integral membrane protein family. | Rv1269c, (MTCY50.13), len: 124 aa. Conserved probable exported protein with putative N-terminal signal sequence. Similar to Mycobacterium tuberculosis protein Rv1813c|Y0DU_MYCTU|Q50620 hypothetical protein cy1a11.30 (137 aa), FASTA scores: E(): 9e-21, (41.6% identity in 137 aa overlap). | 0.457 |
| Rv3005c | Rv1269c | Rv3005c | Rv1269c | Rv3005c, (MTV012.19c), len: 279 aa. Conserved hypothetical protein, equivalent to O33110|MLCB637.18|ML1698 hypothetical 29.5 KDA protein from Mycobacterium leprae (277 aa), FASTA scores: opt: 1245,E(): 1.2e-65, (70.5% identity in 278 aa overlap). Also similar, but longer approximately 100 aa in N-terminus, to other hypothetical proteins, few membrane proteins, e.g. Q9RKN9|SCC75A.35 putative membrane protein from Streptomyces coelicolor (180 aa), FASTA scores: opt: 326,E(): 3.9e-12, (44.2% identity in 138 aa overlap); P96694|YDFP|AB001488 hypothetical protein from Bacillus subtilis (129 [...] | Rv1269c, (MTCY50.13), len: 124 aa. Conserved probable exported protein with putative N-terminal signal sequence. Similar to Mycobacterium tuberculosis protein Rv1813c|Y0DU_MYCTU|Q50620 hypothetical protein cy1a11.30 (137 aa), FASTA scores: E(): 9e-21, (41.6% identity in 137 aa overlap). | 0.651 |
| Rv3005c | sseA | Rv3005c | Rv3283 | Rv3005c, (MTV012.19c), len: 279 aa. Conserved hypothetical protein, equivalent to O33110|MLCB637.18|ML1698 hypothetical 29.5 KDA protein from Mycobacterium leprae (277 aa), FASTA scores: opt: 1245,E(): 1.2e-65, (70.5% identity in 278 aa overlap). Also similar, but longer approximately 100 aa in N-terminus, to other hypothetical proteins, few membrane proteins, e.g. Q9RKN9|SCC75A.35 putative membrane protein from Streptomyces coelicolor (180 aa), FASTA scores: opt: 326,E(): 3.9e-12, (44.2% identity in 138 aa overlap); P96694|YDFP|AB001488 hypothetical protein from Bacillus subtilis (129 [...] | Rv3283, (MTCY71.23), len: 297 aa. Probable sseA,thiosulfate sulfurtransferase, equivalent P46700|THT2_MYCLE|SSEA|ML0728|B1308_C1_127 putative thiosulfate sulfurtransferase SSEA from Mycobacterium leprae (296 aa), FASTA scores: opt: 1742, E(): 5.5e-108,(83.45% identity in 296 aa overlap). Also highly similar to others e.g. Q9RXT9|DR0217 from Deinococcus radiodurans (286 aa), FASTA scores: opt: 1057, E(): 1.2e-62, (53.86% identity in 273 aa overlap); P16385|THTR_SACER|CYSA from Saccharopolyspora erythraea (Streptomyces erythraeus) (281 aa), FASTA scores: opt: 1006, E(): 2.7e-59, (51.25% [...] | 0.821 |
| lprA | Rv1268c | Rv1270c | Rv1268c | Possible lipoprotein LprA; Constitutes a host TLR2 agonist (toll-like receptor), shown experimentally for human and mouse. In host cells full-length (acylated) protein acts as a TLR2 agonist, inducing human and murine macrophages to produce cytokines, inducing murine dendritic cell maturation and cytokine production and inhibiting antibody processing in murine macrophages. Binds diacylated phosphatidyl-myo-inositol mannosides (PIMs). Does not induce murine macrophage apoptosis or necrosis. Non- acylated protein does not act as a TLR2 agonist. Requires only host TLR2 as receptors to eli [...] | Hypothetical protein; Rv1268c, (MTCY50.14), len: 232 aa. Hypothetical unknown protein, probably secreted protein : contains possible signal peptide sequence (score 7.9 at residue 28). Predicted to be an outer membrane protein (See Song et al.,2008). | 0.402 |
| lprA | Rv1269c | Rv1270c | Rv1269c | Possible lipoprotein LprA; Constitutes a host TLR2 agonist (toll-like receptor), shown experimentally for human and mouse. In host cells full-length (acylated) protein acts as a TLR2 agonist, inducing human and murine macrophages to produce cytokines, inducing murine dendritic cell maturation and cytokine production and inhibiting antibody processing in murine macrophages. Binds diacylated phosphatidyl-myo-inositol mannosides (PIMs). Does not induce murine macrophage apoptosis or necrosis. Non- acylated protein does not act as a TLR2 agonist. Requires only host TLR2 as receptors to eli [...] | Rv1269c, (MTCY50.13), len: 124 aa. Conserved probable exported protein with putative N-terminal signal sequence. Similar to Mycobacterium tuberculosis protein Rv1813c|Y0DU_MYCTU|Q50620 hypothetical protein cy1a11.30 (137 aa), FASTA scores: E(): 9e-21, (41.6% identity in 137 aa overlap). | 0.668 |
| lprA | mmpL4 | Rv1270c | Rv0450c | Possible lipoprotein LprA; Constitutes a host TLR2 agonist (toll-like receptor), shown experimentally for human and mouse. In host cells full-length (acylated) protein acts as a TLR2 agonist, inducing human and murine macrophages to produce cytokines, inducing murine dendritic cell maturation and cytokine production and inhibiting antibody processing in murine macrophages. Binds diacylated phosphatidyl-myo-inositol mannosides (PIMs). Does not induce murine macrophage apoptosis or necrosis. Non- acylated protein does not act as a TLR2 agonist. Requires only host TLR2 as receptors to eli [...] | Probable conserved transmembrane transport protein MmpL4; Part of an export system, which is required for biosynthesis and secretion of siderophores. Essential for normal replication during the active-growth phase of the murine tuberculosis model. | 0.423 |
| mmpL4 | Rv1269c | Rv0450c | Rv1269c | Probable conserved transmembrane transport protein MmpL4; Part of an export system, which is required for biosynthesis and secretion of siderophores. Essential for normal replication during the active-growth phase of the murine tuberculosis model. | Rv1269c, (MTCY50.13), len: 124 aa. Conserved probable exported protein with putative N-terminal signal sequence. Similar to Mycobacterium tuberculosis protein Rv1813c|Y0DU_MYCTU|Q50620 hypothetical protein cy1a11.30 (137 aa), FASTA scores: E(): 9e-21, (41.6% identity in 137 aa overlap). | 0.571 |
| mmpL4 | lprA | Rv0450c | Rv1270c | Probable conserved transmembrane transport protein MmpL4; Part of an export system, which is required for biosynthesis and secretion of siderophores. Essential for normal replication during the active-growth phase of the murine tuberculosis model. | Possible lipoprotein LprA; Constitutes a host TLR2 agonist (toll-like receptor), shown experimentally for human and mouse. In host cells full-length (acylated) protein acts as a TLR2 agonist, inducing human and murine macrophages to produce cytokines, inducing murine dendritic cell maturation and cytokine production and inhibiting antibody processing in murine macrophages. Binds diacylated phosphatidyl-myo-inositol mannosides (PIMs). Does not induce murine macrophage apoptosis or necrosis. Non- acylated protein does not act as a TLR2 agonist. Requires only host TLR2 as receptors to eli [...] | 0.423 |
| sseA | Rv1269c | Rv3283 | Rv1269c | Rv3283, (MTCY71.23), len: 297 aa. Probable sseA,thiosulfate sulfurtransferase, equivalent P46700|THT2_MYCLE|SSEA|ML0728|B1308_C1_127 putative thiosulfate sulfurtransferase SSEA from Mycobacterium leprae (296 aa), FASTA scores: opt: 1742, E(): 5.5e-108,(83.45% identity in 296 aa overlap). Also highly similar to others e.g. Q9RXT9|DR0217 from Deinococcus radiodurans (286 aa), FASTA scores: opt: 1057, E(): 1.2e-62, (53.86% identity in 273 aa overlap); P16385|THTR_SACER|CYSA from Saccharopolyspora erythraea (Streptomyces erythraeus) (281 aa), FASTA scores: opt: 1006, E(): 2.7e-59, (51.25% [...] | Rv1269c, (MTCY50.13), len: 124 aa. Conserved probable exported protein with putative N-terminal signal sequence. Similar to Mycobacterium tuberculosis protein Rv1813c|Y0DU_MYCTU|Q50620 hypothetical protein cy1a11.30 (137 aa), FASTA scores: E(): 9e-21, (41.6% identity in 137 aa overlap). | 0.811 |
| sseA | Rv3005c | Rv3283 | Rv3005c | Rv3283, (MTCY71.23), len: 297 aa. Probable sseA,thiosulfate sulfurtransferase, equivalent P46700|THT2_MYCLE|SSEA|ML0728|B1308_C1_127 putative thiosulfate sulfurtransferase SSEA from Mycobacterium leprae (296 aa), FASTA scores: opt: 1742, E(): 5.5e-108,(83.45% identity in 296 aa overlap). Also highly similar to others e.g. Q9RXT9|DR0217 from Deinococcus radiodurans (286 aa), FASTA scores: opt: 1057, E(): 1.2e-62, (53.86% identity in 273 aa overlap); P16385|THTR_SACER|CYSA from Saccharopolyspora erythraea (Streptomyces erythraeus) (281 aa), FASTA scores: opt: 1006, E(): 2.7e-59, (51.25% [...] | Rv3005c, (MTV012.19c), len: 279 aa. Conserved hypothetical protein, equivalent to O33110|MLCB637.18|ML1698 hypothetical 29.5 KDA protein from Mycobacterium leprae (277 aa), FASTA scores: opt: 1245,E(): 1.2e-65, (70.5% identity in 278 aa overlap). Also similar, but longer approximately 100 aa in N-terminus, to other hypothetical proteins, few membrane proteins, e.g. Q9RKN9|SCC75A.35 putative membrane protein from Streptomyces coelicolor (180 aa), FASTA scores: opt: 326,E(): 3.9e-12, (44.2% identity in 138 aa overlap); P96694|YDFP|AB001488 hypothetical protein from Bacillus subtilis (129 [...] | 0.821 |