| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PE_PGRS38 | Rv2159c | Rv2162c | Rv2159c | PE-PGRS family protein PE_PGRS38; Rv2162c, (MTCY270.06), len: 532 aa. PE_PGRS38,Member of M. tuberculosis PE_PGRS family (see citations below). FASTA score: Y03A_MYCTU Q 10637 hypothetical glycine-rich 49.6 kDa protein (603 aa) op t: 1798 z-score: 1220.0 E(): 0; (55.4% identity in 590 aa overlap). This region is a possible MT-complex-specific genomic island (See Becq et al., 2007). | Conserved protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | 0.780 |
| PE_PGRS38 | Rv2160c | Rv2162c | Rv2160c | PE-PGRS family protein PE_PGRS38; Rv2162c, (MTCY270.06), len: 532 aa. PE_PGRS38,Member of M. tuberculosis PE_PGRS family (see citations below). FASTA score: Y03A_MYCTU Q 10637 hypothetical glycine-rich 49.6 kDa protein (603 aa) op t: 1798 z-score: 1220.0 E(): 0; (55.4% identity in 590 aa overlap). This region is a possible MT-complex-specific genomic island (See Becq et al., 2007). | Rv2160c, (MTCY270.08), len: 113 aa. Conserved hypothetical protein, possibly a TetR-family transcriptional regulator, similar to C-terminal half of AL512667_12|Q9AD73|SCK31.01c putative TetR-family transcriptional regulator from Streptomyces coelicolor (200 aa), while Rv2160A is similar to the N-terminal half of 2SCK31.01c. This suggests possible frameshift near 2421978 but sequence of this region has been checked and is also identical in strain CDC1551. This region is a possible MT-complex-specific genomic island (See Becq et al.,2007). | 0.769 |
| PE_PGRS38 | Rv2161c | Rv2162c | Rv2161c | PE-PGRS family protein PE_PGRS38; Rv2162c, (MTCY270.06), len: 532 aa. PE_PGRS38,Member of M. tuberculosis PE_PGRS family (see citations below). FASTA score: Y03A_MYCTU Q 10637 hypothetical glycine-rich 49.6 kDa protein (603 aa) op t: 1798 z-score: 1220.0 E(): 0; (55.4% identity in 590 aa overlap). This region is a possible MT-complex-specific genomic island (See Becq et al., 2007). | Conserved protein; Rv2161c, (MTCY270.07), len: 288 aa. Conserved protein; shows some similarity to protein involved in lincomycin production and to other M. tuberculosis proteins e.g. Rv0953c, Rv0791c, Rv0132c, Rv2951c, Rv1855c. FASTA best: Q54379 (78-11) lincomycin production genes (295 aa) opt: 243, E(): 2.4e-09; (29.5% identity in 285 aa overlap). This region is a possible MT-complex-specific genomic island (See Becq et al., 2007). | 0.898 |
| PE_PGRS38 | ftsQ | Rv2162c | Rv2151c | PE-PGRS family protein PE_PGRS38; Rv2162c, (MTCY270.06), len: 532 aa. PE_PGRS38,Member of M. tuberculosis PE_PGRS family (see citations below). FASTA score: Y03A_MYCTU Q 10637 hypothetical glycine-rich 49.6 kDa protein (603 aa) op t: 1798 z-score: 1220.0 E(): 0; (55.4% identity in 590 aa overlap). This region is a possible MT-complex-specific genomic island (See Becq et al., 2007). | Possible cell division protein FtsQ; Essential cell division protein. | 0.439 |
| PE_PGRS38 | murE | Rv2162c | Rv2158c | PE-PGRS family protein PE_PGRS38; Rv2162c, (MTCY270.06), len: 532 aa. PE_PGRS38,Member of M. tuberculosis PE_PGRS family (see citations below). FASTA score: Y03A_MYCTU Q 10637 hypothetical glycine-rich 49.6 kDa protein (603 aa) op t: 1798 z-score: 1220.0 E(): 0; (55.4% identity in 590 aa overlap). This region is a possible MT-complex-specific genomic island (See Becq et al., 2007). | Probable UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase MurE; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. | 0.436 |
| Rv0148 | Rv2159c | Rv0148 | Rv2159c | Rv0148, (MTCI5.22), len: 286 aa. Probable short-chain dehydrogenase, similar to others, in particular Estradiol 17 beta-dehydrogenases, e.g. DHB4_MOUSE|P51660 estradiol 17 beta-dehydrogenase 4 (735 aa), FASTA scores: opt: 952, E(): 0, (52.5% identity in 276 aa overlap). Contains PS00061 Short-chain alcohol dehydrogenase family signature. Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Conserved protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | 0.835 |
| Rv2159c | PE_PGRS38 | Rv2159c | Rv2162c | Conserved protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | PE-PGRS family protein PE_PGRS38; Rv2162c, (MTCY270.06), len: 532 aa. PE_PGRS38,Member of M. tuberculosis PE_PGRS family (see citations below). FASTA score: Y03A_MYCTU Q 10637 hypothetical glycine-rich 49.6 kDa protein (603 aa) op t: 1798 z-score: 1220.0 E(): 0; (55.4% identity in 590 aa overlap). This region is a possible MT-complex-specific genomic island (See Becq et al., 2007). | 0.780 |
| Rv2159c | Rv0148 | Rv2159c | Rv0148 | Conserved protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | Rv0148, (MTCI5.22), len: 286 aa. Probable short-chain dehydrogenase, similar to others, in particular Estradiol 17 beta-dehydrogenases, e.g. DHB4_MOUSE|P51660 estradiol 17 beta-dehydrogenase 4 (735 aa), FASTA scores: opt: 952, E(): 0, (52.5% identity in 276 aa overlap). Contains PS00061 Short-chain alcohol dehydrogenase family signature. Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.835 |
| Rv2159c | Rv2160A | Rv2159c | Rv2160A | Conserved protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | Rv2160A, len: 211 aa. Conserved hypothetical protein, possibly a TetR-family transcriptional regulator,similar to N-terminal half of AL512667_12|Q9AD73|SCK31.01c putative TetR-family transcriptional regulator from Streptomyces coelicolor (200 aa), FASTA scores: opt: 285,E(): 1.4e-08, (51.042% identity in 96 aa overlap). Next gene, Rv2160c, is similar to C-terminal half of 2SCK31.01c suggesting possible frameshift near 2421978 but sequence of this region has been checked and is also identical in strain CDC1551. This region is a possible MT-complex-specific genomic island (See Becq et al [...] | 0.963 |
| Rv2159c | Rv2160c | Rv2159c | Rv2160c | Conserved protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | Rv2160c, (MTCY270.08), len: 113 aa. Conserved hypothetical protein, possibly a TetR-family transcriptional regulator, similar to C-terminal half of AL512667_12|Q9AD73|SCK31.01c putative TetR-family transcriptional regulator from Streptomyces coelicolor (200 aa), while Rv2160A is similar to the N-terminal half of 2SCK31.01c. This suggests possible frameshift near 2421978 but sequence of this region has been checked and is also identical in strain CDC1551. This region is a possible MT-complex-specific genomic island (See Becq et al.,2007). | 0.983 |
| Rv2159c | Rv2161c | Rv2159c | Rv2161c | Conserved protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | Conserved protein; Rv2161c, (MTCY270.07), len: 288 aa. Conserved protein; shows some similarity to protein involved in lincomycin production and to other M. tuberculosis proteins e.g. Rv0953c, Rv0791c, Rv0132c, Rv2951c, Rv1855c. FASTA best: Q54379 (78-11) lincomycin production genes (295 aa) opt: 243, E(): 2.4e-09; (29.5% identity in 285 aa overlap). This region is a possible MT-complex-specific genomic island (See Becq et al., 2007). | 0.981 |
| Rv2159c | ftsQ | Rv2159c | Rv2151c | Conserved protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | Possible cell division protein FtsQ; Essential cell division protein. | 0.827 |
| Rv2159c | murD | Rv2159c | Rv2155c | Conserved protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | Probable UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.727 |
| Rv2159c | murE | Rv2159c | Rv2158c | Conserved protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | Probable UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase MurE; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. | 0.848 |
| Rv2159c | murF | Rv2159c | Rv2157c | Conserved protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | Probable UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanyl ligase MurF; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. | 0.749 |
| Rv2159c | murX | Rv2159c | Rv2156c | Conserved protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | Probable phospho-N-acetylmuramoyl-pentappeptidetransferase MurX; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan. | 0.747 |
| Rv2160A | Rv2159c | Rv2160A | Rv2159c | Rv2160A, len: 211 aa. Conserved hypothetical protein, possibly a TetR-family transcriptional regulator,similar to N-terminal half of AL512667_12|Q9AD73|SCK31.01c putative TetR-family transcriptional regulator from Streptomyces coelicolor (200 aa), FASTA scores: opt: 285,E(): 1.4e-08, (51.042% identity in 96 aa overlap). Next gene, Rv2160c, is similar to C-terminal half of 2SCK31.01c suggesting possible frameshift near 2421978 but sequence of this region has been checked and is also identical in strain CDC1551. This region is a possible MT-complex-specific genomic island (See Becq et al [...] | Conserved protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | 0.963 |
| Rv2160A | Rv2160c | Rv2160A | Rv2160c | Rv2160A, len: 211 aa. Conserved hypothetical protein, possibly a TetR-family transcriptional regulator,similar to N-terminal half of AL512667_12|Q9AD73|SCK31.01c putative TetR-family transcriptional regulator from Streptomyces coelicolor (200 aa), FASTA scores: opt: 285,E(): 1.4e-08, (51.042% identity in 96 aa overlap). Next gene, Rv2160c, is similar to C-terminal half of 2SCK31.01c suggesting possible frameshift near 2421978 but sequence of this region has been checked and is also identical in strain CDC1551. This region is a possible MT-complex-specific genomic island (See Becq et al [...] | Rv2160c, (MTCY270.08), len: 113 aa. Conserved hypothetical protein, possibly a TetR-family transcriptional regulator, similar to C-terminal half of AL512667_12|Q9AD73|SCK31.01c putative TetR-family transcriptional regulator from Streptomyces coelicolor (200 aa), while Rv2160A is similar to the N-terminal half of 2SCK31.01c. This suggests possible frameshift near 2421978 but sequence of this region has been checked and is also identical in strain CDC1551. This region is a possible MT-complex-specific genomic island (See Becq et al.,2007). | 0.981 |
| Rv2160A | Rv2161c | Rv2160A | Rv2161c | Rv2160A, len: 211 aa. Conserved hypothetical protein, possibly a TetR-family transcriptional regulator,similar to N-terminal half of AL512667_12|Q9AD73|SCK31.01c putative TetR-family transcriptional regulator from Streptomyces coelicolor (200 aa), FASTA scores: opt: 285,E(): 1.4e-08, (51.042% identity in 96 aa overlap). Next gene, Rv2160c, is similar to C-terminal half of 2SCK31.01c suggesting possible frameshift near 2421978 but sequence of this region has been checked and is also identical in strain CDC1551. This region is a possible MT-complex-specific genomic island (See Becq et al [...] | Conserved protein; Rv2161c, (MTCY270.07), len: 288 aa. Conserved protein; shows some similarity to protein involved in lincomycin production and to other M. tuberculosis proteins e.g. Rv0953c, Rv0791c, Rv0132c, Rv2951c, Rv1855c. FASTA best: Q54379 (78-11) lincomycin production genes (295 aa) opt: 243, E(): 2.4e-09; (29.5% identity in 285 aa overlap). This region is a possible MT-complex-specific genomic island (See Becq et al., 2007). | 0.874 |
| Rv2160A | ftsQ | Rv2160A | Rv2151c | Rv2160A, len: 211 aa. Conserved hypothetical protein, possibly a TetR-family transcriptional regulator,similar to N-terminal half of AL512667_12|Q9AD73|SCK31.01c putative TetR-family transcriptional regulator from Streptomyces coelicolor (200 aa), FASTA scores: opt: 285,E(): 1.4e-08, (51.042% identity in 96 aa overlap). Next gene, Rv2160c, is similar to C-terminal half of 2SCK31.01c suggesting possible frameshift near 2421978 but sequence of this region has been checked and is also identical in strain CDC1551. This region is a possible MT-complex-specific genomic island (See Becq et al [...] | Possible cell division protein FtsQ; Essential cell division protein. | 0.715 |
