Rv2552c, (MTCY159.04), len: 269 aa. Probable aroE,shikimate 5-dehydrogenase, equivalent to Q9CCS7|AROE|ML0515 putative shikimate 5-dehydrogenase from Mycobacterium leprae (278 aa), FASTA scores: opt: 1452, E(): 1.8e-77,(81.5% identity in 270 aa overlap). Also highly similar,but longer 101 aa, to Q9KH59|AROE putative shikimate dehydrogenase (fragment) from Mycobacterium marinum (148 aa), FASTA scores: opt: 729, E(): 1.3e-35, (76.35% identity in 148 overlap); Q9F7W3|AROE from Mycobacterium ulcerans (148 aa), FASTA scores: opt: 718, E(): 5.9e-35, (75.7% identity in 148 aa overlap). And al [...]

Probable conserved membrane protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.

Rv2551c, (MTCY159.05), len: 139 aa. Conserved hypothetical protein, similar to the second part of Q9XAP1|SC10A7.34c putative type IV peptidase from Streptomyces coelicolor (259 aa), FASTA scores: opt: 243,E(): 7.4e-08, (40.95% identity in 144 aa overlap). Also some similarity with other proteins e.g. AAK58497|GSPO GSPO protein from Acetobacter diazotrophicus (261 aa), FASTA scores: opt: 152, E(): 0.025, (33.35% identity in 135 aa overlap).

Rv2556c, (MTCY09C4.12), len: 129 aa. Conserved hypothetical protein, highly similar to others e.g. Q9EWY5|2SCG38.34 conserved hypothetical protein from Streptomyces coelicolor (140 aa), FASTA scores: opt: 488,E(): 8.2e-26, (58.8% identity in 131 aa overlap); Q9L9G4|NOVD NOVD protein from Streptomyces sphaeroides (143 aa), FASTA scores: opt: 474, E(): 7.2e-25, (60.85% identity in 120 aa overlap); Q9X2I5|TM1872 from Thermotoga maritima (132 aa), FASTA scores: opt: 270, E(): 2.7e-11, (39.55% identity in 129 aa overlap); etc; Belongs to the UPF0047 family.

Conserved protein; Rv0038, (MTCY10H4.38), len: 202 aa. Conserved protein, similar to many; Belongs to the UPF0301 (AlgH) family.

Probable integrase/recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity).

Rv3022A, len: 104 aa. PE29, Member of the Mycobacterium tuberculosis PE family (see Brennan and Delogu, 2002), similar to many others e.g. Rv0285|AL021930_12 from Mycobacterium tuberculosis (102 aa), FASTA scores: opt: 497, E(): 3e-21, (80.39% identity in 102 aa overlap); etc.

Probable holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

Proteasome accessory factor B PafB; Part of the pafABC operon, however PafB does not seem to be involved in pupylation or substrate degradation. Appears to play at least a small role in resistance to reactive nitrogen intermediates (RNI) in vitro.