node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
alr | ddlA | Rv3423c | Rv2981c | Alanine racemase Alr; Catalyzes the interconversion of L-alanine and D-alanine. D- alanine plays a key role in peptidoglycan cross-linking. | Probable D-alanine--D-alanine ligase DdlA (D-alanylalanine synthetase) (D-ala-D-ala ligase); Catalyzes the ATP-driven ligation of two D-alanine molecules to form the D-alanyl-D-alanine dipeptide. This molecule is a key building block in peptidoglycan biosynthesis. | 0.998 |
alr | ftsW | Rv3423c | Rv2154c | Alanine racemase Alr; Catalyzes the interconversion of L-alanine and D-alanine. D- alanine plays a key role in peptidoglycan cross-linking. | FtsW-like protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.637 |
alr | murB | Rv3423c | Rv0482 | Alanine racemase Alr; Catalyzes the interconversion of L-alanine and D-alanine. D- alanine plays a key role in peptidoglycan cross-linking. | Probable UDP-N-acetylenolpyruvoylglucosamine reductase MurB (UDP-N-acetylmuramate dehydrogenase); Cell wall formation. | 0.624 |
alr | murC | Rv3423c | Rv2152c | Alanine racemase Alr; Catalyzes the interconversion of L-alanine and D-alanine. D- alanine plays a key role in peptidoglycan cross-linking. | Probable UDP-N-acetylmuramate-alanine ligase MurC; Cell wall formation; Belongs to the MurCDEF family. | 0.753 |
alr | murD | Rv3423c | Rv2155c | Alanine racemase Alr; Catalyzes the interconversion of L-alanine and D-alanine. D- alanine plays a key role in peptidoglycan cross-linking. | Probable UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.839 |
alr | murE | Rv3423c | Rv2158c | Alanine racemase Alr; Catalyzes the interconversion of L-alanine and D-alanine. D- alanine plays a key role in peptidoglycan cross-linking. | Probable UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase MurE; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. | 0.650 |
alr | murF | Rv3423c | Rv2157c | Alanine racemase Alr; Catalyzes the interconversion of L-alanine and D-alanine. D- alanine plays a key role in peptidoglycan cross-linking. | Probable UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanyl ligase MurF; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. | 0.987 |
alr | murG | Rv3423c | Rv2153c | Alanine racemase Alr; Catalyzes the interconversion of L-alanine and D-alanine. D- alanine plays a key role in peptidoglycan cross-linking. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II). | 0.711 |
alr | murX | Rv3423c | Rv2156c | Alanine racemase Alr; Catalyzes the interconversion of L-alanine and D-alanine. D- alanine plays a key role in peptidoglycan cross-linking. | Probable phospho-N-acetylmuramoyl-pentappeptidetransferase MurX; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan. | 0.514 |
ddlA | alr | Rv2981c | Rv3423c | Probable D-alanine--D-alanine ligase DdlA (D-alanylalanine synthetase) (D-ala-D-ala ligase); Catalyzes the ATP-driven ligation of two D-alanine molecules to form the D-alanyl-D-alanine dipeptide. This molecule is a key building block in peptidoglycan biosynthesis. | Alanine racemase Alr; Catalyzes the interconversion of L-alanine and D-alanine. D- alanine plays a key role in peptidoglycan cross-linking. | 0.998 |
ddlA | ftsW | Rv2981c | Rv2154c | Probable D-alanine--D-alanine ligase DdlA (D-alanylalanine synthetase) (D-ala-D-ala ligase); Catalyzes the ATP-driven ligation of two D-alanine molecules to form the D-alanyl-D-alanine dipeptide. This molecule is a key building block in peptidoglycan biosynthesis. | FtsW-like protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.876 |
ddlA | ftsZ | Rv2981c | Rv2150c | Probable D-alanine--D-alanine ligase DdlA (D-alanylalanine synthetase) (D-ala-D-ala ligase); Catalyzes the ATP-driven ligation of two D-alanine molecules to form the D-alanyl-D-alanine dipeptide. This molecule is a key building block in peptidoglycan biosynthesis. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.878 |
ddlA | murB | Rv2981c | Rv0482 | Probable D-alanine--D-alanine ligase DdlA (D-alanylalanine synthetase) (D-ala-D-ala ligase); Catalyzes the ATP-driven ligation of two D-alanine molecules to form the D-alanyl-D-alanine dipeptide. This molecule is a key building block in peptidoglycan biosynthesis. | Probable UDP-N-acetylenolpyruvoylglucosamine reductase MurB (UDP-N-acetylmuramate dehydrogenase); Cell wall formation. | 0.872 |
ddlA | murC | Rv2981c | Rv2152c | Probable D-alanine--D-alanine ligase DdlA (D-alanylalanine synthetase) (D-ala-D-ala ligase); Catalyzes the ATP-driven ligation of two D-alanine molecules to form the D-alanyl-D-alanine dipeptide. This molecule is a key building block in peptidoglycan biosynthesis. | Probable UDP-N-acetylmuramate-alanine ligase MurC; Cell wall formation; Belongs to the MurCDEF family. | 0.993 |
ddlA | murD | Rv2981c | Rv2155c | Probable D-alanine--D-alanine ligase DdlA (D-alanylalanine synthetase) (D-ala-D-ala ligase); Catalyzes the ATP-driven ligation of two D-alanine molecules to form the D-alanyl-D-alanine dipeptide. This molecule is a key building block in peptidoglycan biosynthesis. | Probable UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.959 |
ddlA | murE | Rv2981c | Rv2158c | Probable D-alanine--D-alanine ligase DdlA (D-alanylalanine synthetase) (D-ala-D-ala ligase); Catalyzes the ATP-driven ligation of two D-alanine molecules to form the D-alanyl-D-alanine dipeptide. This molecule is a key building block in peptidoglycan biosynthesis. | Probable UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase MurE; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. | 0.951 |
ddlA | murF | Rv2981c | Rv2157c | Probable D-alanine--D-alanine ligase DdlA (D-alanylalanine synthetase) (D-ala-D-ala ligase); Catalyzes the ATP-driven ligation of two D-alanine molecules to form the D-alanyl-D-alanine dipeptide. This molecule is a key building block in peptidoglycan biosynthesis. | Probable UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanyl ligase MurF; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. | 0.998 |
ddlA | murG | Rv2981c | Rv2153c | Probable D-alanine--D-alanine ligase DdlA (D-alanylalanine synthetase) (D-ala-D-ala ligase); Catalyzes the ATP-driven ligation of two D-alanine molecules to form the D-alanyl-D-alanine dipeptide. This molecule is a key building block in peptidoglycan biosynthesis. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II). | 0.964 |
ddlA | murX | Rv2981c | Rv2156c | Probable D-alanine--D-alanine ligase DdlA (D-alanylalanine synthetase) (D-ala-D-ala ligase); Catalyzes the ATP-driven ligation of two D-alanine molecules to form the D-alanyl-D-alanine dipeptide. This molecule is a key building block in peptidoglycan biosynthesis. | Probable phospho-N-acetylmuramoyl-pentappeptidetransferase MurX; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan. | 0.848 |
ftsW | alr | Rv2154c | Rv3423c | FtsW-like protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | Alanine racemase Alr; Catalyzes the interconversion of L-alanine and D-alanine. D- alanine plays a key role in peptidoglycan cross-linking. | 0.637 |