node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rv0187 | Rv3030 | Rv0187 | Rv3030 | Probable O-methyltransferase; Catechol O-methyltransferase that can use various catechol- like compounds such as gallic acid (GA), 3,4-dihydroxy-5-methoxy- benzoic acid (5OMeBA), protocatechuic acid (PCA), 3,4-dihydroxy- benzaldehyde (DHA), dopamine, caffeic acid (CA), luteolin, quercetin, and 5-hydroxyuridine; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. | Conserved protein; Probable S-adenosylmethionine-dependent methyltransferase required for the 6-O-methylation of the polysaccharide backbone of 6-O- methylglucosyl lipopolysaccharides (MGLP). | 0.648 |
Rv0187 | Rv3032 | Rv0187 | Rv3032 | Probable O-methyltransferase; Catechol O-methyltransferase that can use various catechol- like compounds such as gallic acid (GA), 3,4-dihydroxy-5-methoxy- benzoic acid (5OMeBA), protocatechuic acid (PCA), 3,4-dihydroxy- benzaldehyde (DHA), dopamine, caffeic acid (CA), luteolin, quercetin, and 5-hydroxyuridine; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. | Alpha (1->4) glucosyltransferase; Glucosyltransferase that uses UDP-glucose as the sugar donor to elongate alpha-(1->4)-glucans. Is involved in the biosynthesis of both 6-O-methylglucosyl lipopolysaccharides (MGLP) and glycogen. May also use ADP-glucose as substrate. | 0.408 |
Rv0187 | Rv3034c | Rv0187 | Rv3034c | Probable O-methyltransferase; Catechol O-methyltransferase that can use various catechol- like compounds such as gallic acid (GA), 3,4-dihydroxy-5-methoxy- benzoic acid (5OMeBA), protocatechuic acid (PCA), 3,4-dihydroxy- benzaldehyde (DHA), dopamine, caffeic acid (CA), luteolin, quercetin, and 5-hydroxyuridine; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. | Possible transferase; Putative acetyltransferase that is probably involved in the biosynthesis of 6-O-methylglucosyl lipopolysaccharides (MGLP). | 0.665 |
Rv0187 | gpgS | Rv0187 | Rv1208 | Probable O-methyltransferase; Catechol O-methyltransferase that can use various catechol- like compounds such as gallic acid (GA), 3,4-dihydroxy-5-methoxy- benzoic acid (5OMeBA), protocatechuic acid (PCA), 3,4-dihydroxy- benzaldehyde (DHA), dopamine, caffeic acid (CA), luteolin, quercetin, and 5-hydroxyuridine; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. | Probable glucosyl-3-phosphoglycerate synthase GpgS; Involved in the biosynthesis of 6-O-methylglucose lipopolysaccarides (MGLPs). Catalyzes the transfer of a glucose (Glc) moiety from uridine diphosphate (UDP-Glc) to the position 2 of 3- phospho-D-glycerate (3-PGA) to form glucosyl-3-phosphoglycerate (GPG). | 0.807 |
Rv0187 | octT | Rv0187 | Rv2418c | Probable O-methyltransferase; Catechol O-methyltransferase that can use various catechol- like compounds such as gallic acid (GA), 3,4-dihydroxy-5-methoxy- benzoic acid (5OMeBA), protocatechuic acid (PCA), 3,4-dihydroxy- benzaldehyde (DHA), dopamine, caffeic acid (CA), luteolin, quercetin, and 5-hydroxyuridine; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. | Unknown protein; Sugar octanoyltransferase likely involved in the biosynthesis of mycobacterial methylglucose lipopolysaccharide (MGLP). Catalyzes the transfer of an octanoyl group from octanoyl-CoA to the C6 OH of the second glucose in diglucosylglycerate (DGG). DGG is the preferred acceptor, but to a lesser extent, GG (glucosylglycerate) can also be used as substrate. DGG and GG are the two earliest intermediates in MGLP biosynthesis. | 0.806 |
Rv2186c | Rv2695 | Rv2186c | Rv2695 | Rv2186c, (MTV021.19c), len: 129 aa. Conserved hypothetical protein, equivalent to hypothetical Mycobacterium leprae protein ML0888 (135 aa). FASTA scores: ML0888 opt: 704, E(): 2.9e-43; 80.000% identity in 130 aa overlap CAA18694.1| (AL022602). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al.,2004). | Rv2695, (MTCY05A6.16), len: 235 aa. Conserved hypothetical ala-rich protein, equivalent to Q49994|ML1030|U1764L hypothetical protein from Mycobacterium leprae (232 aa), FASTA scores: opt: 1166,E(): 6.3e-63, (76.95% identity in 230 aa overlap). Also shows some similarity with other hypothetical proteins e.g. Q986S2|MLR7232 hypothetical protein from Rhizobium loti (Mesorhizobium loti) (277 aa), FASTA scores: opt: 150, E(): 0.059, (33.55% identity in 173 aa overlap); CAC47772|SMC03810 hypothetical protein from Rhizobium meliloti (Sinorhizobium meliloti) (269 aa), FASTA scores: opt: 143, E [...] | 0.748 |
Rv2186c | Rv3030 | Rv2186c | Rv3030 | Rv2186c, (MTV021.19c), len: 129 aa. Conserved hypothetical protein, equivalent to hypothetical Mycobacterium leprae protein ML0888 (135 aa). FASTA scores: ML0888 opt: 704, E(): 2.9e-43; 80.000% identity in 130 aa overlap CAA18694.1| (AL022602). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al.,2004). | Conserved protein; Probable S-adenosylmethionine-dependent methyltransferase required for the 6-O-methylation of the polysaccharide backbone of 6-O- methylglucosyl lipopolysaccharides (MGLP). | 0.707 |
Rv2186c | Rv3031 | Rv2186c | Rv3031 | Rv2186c, (MTV021.19c), len: 129 aa. Conserved hypothetical protein, equivalent to hypothetical Mycobacterium leprae protein ML0888 (135 aa). FASTA scores: ML0888 opt: 704, E(): 2.9e-43; 80.000% identity in 130 aa overlap CAA18694.1| (AL022602). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al.,2004). | Conserved protein; Catalyzes the formation of branch points in alpha-glucans by cleavage of an alpha-1,4 glycosidic bond and subsequent transfer of the cleaved-off oligosaccharide to a new alpha-1,6 position (Probable). Is probably involved in the biosynthesis of 6-O-methylglucosyl lipopolysaccharides (MGLP); Belongs to the glycosyl hydrolase 57 family. | 0.749 |
Rv2186c | Rv3032 | Rv2186c | Rv3032 | Rv2186c, (MTV021.19c), len: 129 aa. Conserved hypothetical protein, equivalent to hypothetical Mycobacterium leprae protein ML0888 (135 aa). FASTA scores: ML0888 opt: 704, E(): 2.9e-43; 80.000% identity in 130 aa overlap CAA18694.1| (AL022602). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al.,2004). | Alpha (1->4) glucosyltransferase; Glucosyltransferase that uses UDP-glucose as the sugar donor to elongate alpha-(1->4)-glucans. Is involved in the biosynthesis of both 6-O-methylglucosyl lipopolysaccharides (MGLP) and glycogen. May also use ADP-glucose as substrate. | 0.692 |
Rv2186c | Rv3034c | Rv2186c | Rv3034c | Rv2186c, (MTV021.19c), len: 129 aa. Conserved hypothetical protein, equivalent to hypothetical Mycobacterium leprae protein ML0888 (135 aa). FASTA scores: ML0888 opt: 704, E(): 2.9e-43; 80.000% identity in 130 aa overlap CAA18694.1| (AL022602). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al.,2004). | Possible transferase; Putative acetyltransferase that is probably involved in the biosynthesis of 6-O-methylglucosyl lipopolysaccharides (MGLP). | 0.769 |
Rv2186c | Rv3038c | Rv2186c | Rv3038c | Rv2186c, (MTV021.19c), len: 129 aa. Conserved hypothetical protein, equivalent to hypothetical Mycobacterium leprae protein ML0888 (135 aa). FASTA scores: ML0888 opt: 704, E(): 2.9e-43; 80.000% identity in 130 aa overlap CAA18694.1| (AL022602). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al.,2004). | Conserved protein; Rv3038c, (MTV012.53c), len: 327 aa. Conserved protein, equivalent to Q9CBQ9|ML1723 hypothetical protein from Mycobacterium leprae (327 aa), FASTA scores: opt: 1843, E(): 6.1e-108, (80.75% identity in 327 aa overlap). Weak similarity with e.g. Q9KZI3|SCG8A.16 putative methyltransferase from Streptomyces coelicolor (199 aa),FASTA scores: opt: 227, E(): 3.9e-07, (31.95% identity in 191 aa overlap) and O52570 methyltransferase from Amycolatopsis mediterranei (272 aa), FASTA scores: opt: 228, E(): 4.3e-07, (31.7% identity in 164 aa overlap). Contains PS00044 Bacterial reg [...] | 0.771 |
Rv2186c | octT | Rv2186c | Rv2418c | Rv2186c, (MTV021.19c), len: 129 aa. Conserved hypothetical protein, equivalent to hypothetical Mycobacterium leprae protein ML0888 (135 aa). FASTA scores: ML0888 opt: 704, E(): 2.9e-43; 80.000% identity in 130 aa overlap CAA18694.1| (AL022602). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al.,2004). | Unknown protein; Sugar octanoyltransferase likely involved in the biosynthesis of mycobacterial methylglucose lipopolysaccharide (MGLP). Catalyzes the transfer of an octanoyl group from octanoyl-CoA to the C6 OH of the second glucose in diglucosylglycerate (DGG). DGG is the preferred acceptor, but to a lesser extent, GG (glucosylglycerate) can also be used as substrate. DGG and GG are the two earliest intermediates in MGLP biosynthesis. | 0.778 |
Rv2695 | Rv2186c | Rv2695 | Rv2186c | Rv2695, (MTCY05A6.16), len: 235 aa. Conserved hypothetical ala-rich protein, equivalent to Q49994|ML1030|U1764L hypothetical protein from Mycobacterium leprae (232 aa), FASTA scores: opt: 1166,E(): 6.3e-63, (76.95% identity in 230 aa overlap). Also shows some similarity with other hypothetical proteins e.g. Q986S2|MLR7232 hypothetical protein from Rhizobium loti (Mesorhizobium loti) (277 aa), FASTA scores: opt: 150, E(): 0.059, (33.55% identity in 173 aa overlap); CAC47772|SMC03810 hypothetical protein from Rhizobium meliloti (Sinorhizobium meliloti) (269 aa), FASTA scores: opt: 143, E [...] | Rv2186c, (MTV021.19c), len: 129 aa. Conserved hypothetical protein, equivalent to hypothetical Mycobacterium leprae protein ML0888 (135 aa). FASTA scores: ML0888 opt: 704, E(): 2.9e-43; 80.000% identity in 130 aa overlap CAA18694.1| (AL022602). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al.,2004). | 0.748 |
Rv2695 | Rv3030 | Rv2695 | Rv3030 | Rv2695, (MTCY05A6.16), len: 235 aa. Conserved hypothetical ala-rich protein, equivalent to Q49994|ML1030|U1764L hypothetical protein from Mycobacterium leprae (232 aa), FASTA scores: opt: 1166,E(): 6.3e-63, (76.95% identity in 230 aa overlap). Also shows some similarity with other hypothetical proteins e.g. Q986S2|MLR7232 hypothetical protein from Rhizobium loti (Mesorhizobium loti) (277 aa), FASTA scores: opt: 150, E(): 0.059, (33.55% identity in 173 aa overlap); CAC47772|SMC03810 hypothetical protein from Rhizobium meliloti (Sinorhizobium meliloti) (269 aa), FASTA scores: opt: 143, E [...] | Conserved protein; Probable S-adenosylmethionine-dependent methyltransferase required for the 6-O-methylation of the polysaccharide backbone of 6-O- methylglucosyl lipopolysaccharides (MGLP). | 0.458 |
Rv2695 | Rv3031 | Rv2695 | Rv3031 | Rv2695, (MTCY05A6.16), len: 235 aa. Conserved hypothetical ala-rich protein, equivalent to Q49994|ML1030|U1764L hypothetical protein from Mycobacterium leprae (232 aa), FASTA scores: opt: 1166,E(): 6.3e-63, (76.95% identity in 230 aa overlap). Also shows some similarity with other hypothetical proteins e.g. Q986S2|MLR7232 hypothetical protein from Rhizobium loti (Mesorhizobium loti) (277 aa), FASTA scores: opt: 150, E(): 0.059, (33.55% identity in 173 aa overlap); CAC47772|SMC03810 hypothetical protein from Rhizobium meliloti (Sinorhizobium meliloti) (269 aa), FASTA scores: opt: 143, E [...] | Conserved protein; Catalyzes the formation of branch points in alpha-glucans by cleavage of an alpha-1,4 glycosidic bond and subsequent transfer of the cleaved-off oligosaccharide to a new alpha-1,6 position (Probable). Is probably involved in the biosynthesis of 6-O-methylglucosyl lipopolysaccharides (MGLP); Belongs to the glycosyl hydrolase 57 family. | 0.705 |
Rv2695 | Rv3032 | Rv2695 | Rv3032 | Rv2695, (MTCY05A6.16), len: 235 aa. Conserved hypothetical ala-rich protein, equivalent to Q49994|ML1030|U1764L hypothetical protein from Mycobacterium leprae (232 aa), FASTA scores: opt: 1166,E(): 6.3e-63, (76.95% identity in 230 aa overlap). Also shows some similarity with other hypothetical proteins e.g. Q986S2|MLR7232 hypothetical protein from Rhizobium loti (Mesorhizobium loti) (277 aa), FASTA scores: opt: 150, E(): 0.059, (33.55% identity in 173 aa overlap); CAC47772|SMC03810 hypothetical protein from Rhizobium meliloti (Sinorhizobium meliloti) (269 aa), FASTA scores: opt: 143, E [...] | Alpha (1->4) glucosyltransferase; Glucosyltransferase that uses UDP-glucose as the sugar donor to elongate alpha-(1->4)-glucans. Is involved in the biosynthesis of both 6-O-methylglucosyl lipopolysaccharides (MGLP) and glycogen. May also use ADP-glucose as substrate. | 0.538 |
Rv2695 | Rv3034c | Rv2695 | Rv3034c | Rv2695, (MTCY05A6.16), len: 235 aa. Conserved hypothetical ala-rich protein, equivalent to Q49994|ML1030|U1764L hypothetical protein from Mycobacterium leprae (232 aa), FASTA scores: opt: 1166,E(): 6.3e-63, (76.95% identity in 230 aa overlap). Also shows some similarity with other hypothetical proteins e.g. Q986S2|MLR7232 hypothetical protein from Rhizobium loti (Mesorhizobium loti) (277 aa), FASTA scores: opt: 150, E(): 0.059, (33.55% identity in 173 aa overlap); CAC47772|SMC03810 hypothetical protein from Rhizobium meliloti (Sinorhizobium meliloti) (269 aa), FASTA scores: opt: 143, E [...] | Possible transferase; Putative acetyltransferase that is probably involved in the biosynthesis of 6-O-methylglucosyl lipopolysaccharides (MGLP). | 0.584 |
Rv2695 | Rv3038c | Rv2695 | Rv3038c | Rv2695, (MTCY05A6.16), len: 235 aa. Conserved hypothetical ala-rich protein, equivalent to Q49994|ML1030|U1764L hypothetical protein from Mycobacterium leprae (232 aa), FASTA scores: opt: 1166,E(): 6.3e-63, (76.95% identity in 230 aa overlap). Also shows some similarity with other hypothetical proteins e.g. Q986S2|MLR7232 hypothetical protein from Rhizobium loti (Mesorhizobium loti) (277 aa), FASTA scores: opt: 150, E(): 0.059, (33.55% identity in 173 aa overlap); CAC47772|SMC03810 hypothetical protein from Rhizobium meliloti (Sinorhizobium meliloti) (269 aa), FASTA scores: opt: 143, E [...] | Conserved protein; Rv3038c, (MTV012.53c), len: 327 aa. Conserved protein, equivalent to Q9CBQ9|ML1723 hypothetical protein from Mycobacterium leprae (327 aa), FASTA scores: opt: 1843, E(): 6.1e-108, (80.75% identity in 327 aa overlap). Weak similarity with e.g. Q9KZI3|SCG8A.16 putative methyltransferase from Streptomyces coelicolor (199 aa),FASTA scores: opt: 227, E(): 3.9e-07, (31.95% identity in 191 aa overlap) and O52570 methyltransferase from Amycolatopsis mediterranei (272 aa), FASTA scores: opt: 228, E(): 4.3e-07, (31.7% identity in 164 aa overlap). Contains PS00044 Bacterial reg [...] | 0.559 |
Rv2695 | octT | Rv2695 | Rv2418c | Rv2695, (MTCY05A6.16), len: 235 aa. Conserved hypothetical ala-rich protein, equivalent to Q49994|ML1030|U1764L hypothetical protein from Mycobacterium leprae (232 aa), FASTA scores: opt: 1166,E(): 6.3e-63, (76.95% identity in 230 aa overlap). Also shows some similarity with other hypothetical proteins e.g. Q986S2|MLR7232 hypothetical protein from Rhizobium loti (Mesorhizobium loti) (277 aa), FASTA scores: opt: 150, E(): 0.059, (33.55% identity in 173 aa overlap); CAC47772|SMC03810 hypothetical protein from Rhizobium meliloti (Sinorhizobium meliloti) (269 aa), FASTA scores: opt: 143, E [...] | Unknown protein; Sugar octanoyltransferase likely involved in the biosynthesis of mycobacterial methylglucose lipopolysaccharide (MGLP). Catalyzes the transfer of an octanoyl group from octanoyl-CoA to the C6 OH of the second glucose in diglucosylglycerate (DGG). DGG is the preferred acceptor, but to a lesser extent, GG (glucosylglycerate) can also be used as substrate. DGG and GG are the two earliest intermediates in MGLP biosynthesis. | 0.779 |
Rv3030 | Rv0187 | Rv3030 | Rv0187 | Conserved protein; Probable S-adenosylmethionine-dependent methyltransferase required for the 6-O-methylation of the polysaccharide backbone of 6-O- methylglucosyl lipopolysaccharides (MGLP). | Probable O-methyltransferase; Catechol O-methyltransferase that can use various catechol- like compounds such as gallic acid (GA), 3,4-dihydroxy-5-methoxy- benzoic acid (5OMeBA), protocatechuic acid (PCA), 3,4-dihydroxy- benzaldehyde (DHA), dopamine, caffeic acid (CA), luteolin, quercetin, and 5-hydroxyuridine; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. | 0.648 |