STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rv3475Possible transposase for insertion element IS6110 [second part]; Rv3475, (MTCY13E12.28), len: 328 aa. Probable transposase subunit for IS6110. Identical to many other M. tuberculosis IS6110 transposase subunits. The transposase described here may be made by a frame shifting mechanism during translation that fuses Rv3474 and Rv3475, the sequence UUUUAAAG (directly upstream of Rv3475) maybe responsible for such a frameshifting event (see McAdam et al., 1990). Start changed since first submission (- 18 aa). (328 aa)    
Predicted Functional Partners:
Rv3474
Possible transposase for insertion element IS6110 (fragment); Rv3474, (MTCY13E12.27), len: 108 aa. Probable transposase subunit for IS6110. Identical to many other M. tuberculosis IS6110 transposase subunits. The transposase described here may be made by a frame shifting mechanism during translation that fuses Rv3474 and Rv3475, the sequence UUUUAAAG (directly upstream of Rv3475) maybe responsible for such a frameshifting event (see McAdam et al., 1990). Belongs to the transposase family 8.
  
  
 0.959
Rv1369c
Probable transposase; Rv1369c, (MTCY02B12.03c), len: 328 aa. Probable transposase subunit for IS6110. Identical to many other M. tuberculosis IS6110 transposase subunits. The transposase described here may be made by a frame shifting mechanism during translation that fuses Rv1368c and Rv1369c, the sequence UUUUAAAG (directly upstream of Rv1369c) maybe responsible for such a frameshifting event (see McAdam et al., 1990). Start changed since first submission (+ 34 aa).
  
   
0.860
Rv1756c
Putative transposase; Rv1756c, (MTCY28.22c), len: 328 aa. Putative Transposase subunit for IS6110. Identical to many other M. tuberculosis IS6110 transposase subunits. The transposase described here may be made by a frame shifting mechanism during translation that fuses Rv1756c and Rv1757c, the sequence UUUUAAAG (directly upstream of Rv1756c) maybe responsible for such a frameshifting event (see McAdam et al., 1990). Start changed since first submission (+ 34 aa).
  
   
0.860
Rv1764
Putative transposase; Rv1764, (MTCY28.30), len: 328 aa. Putative Transposase for IS6110 insertion element. Identical to many other M. tuberculosis IS6110 transposase subunits. The transposase described here may be made by a frame shifting mechanism during translation that fuses Rv1763 and Rv1764,the sequence UUUUAAAG (directly upstream of Rv1764) maybe responsible for such a frameshifting event (see McAdam et al., 1990). Start changed since first submission (+ 34 aa).
  
   
0.860
Rv2106
Probable transposase; Rv2106, (MTCY261.02), len: 328 aa. Probable transposase subunit for IS6110. Identical to many other M. tuberculosis IS6110 transposase subunits. The transposase described here may be made by a frame shifting mechanism during translation that fuses Rv2105 and Rv2106, the sequence UUUUAAAG (directly upstream of Rv2106) maybe responsible for such a frameshifting event (see McAdam et al., 1990). Start changed since first submission (+ 16 aa).
  
   
0.860
Rv2167c
Probable transposase; Rv2167c, (MTCY270.01), len: 328 aa. Probable IS6110 transposase. Identical to many other M. tuberculosis IS6110 transposase subunits. The transposase described here may be made by a frame shifting mechanism during translation that fuses Rv2167c and Rv2168c, the sequence UUUUAAAG (directly upstream of Rv2167c) maybe responsible for such a frameshifting event (see McAdam et al., 1990). Start changed since first submission (- 18 aa).
  
   
0.860
Rv2279
Probable transposase; Rv2279, (MTCY339.31c), len: 328 aa. Probable IS6110 transposase. Identical to many other M. tuberculosis IS6110 transposase subunits. The transposase described here may be made by a frame shifting mechanism during translation that fuses Rv2278 and Rv2279, the sequence UUUUAAAG (directly upstream of Rv2279) maybe responsible for such a frameshifting event (see McAdam et al., 1990). Start changed since first submission (+ 16 aa).
  
   
0.860
Rv2355
Probable transposase; Rv2355, (MTCY98.24), len: 328 aa. Probable IS6110 transposase. Identical to many other M. tuberculosis IS6110 transposase subunits. The transposase described here may be made by a frame shifting mechanism during translation that fuses Rv2354 and Rv2355, the sequence UUUUAAAG (directly upstream of Rv2355) maybe responsible for such a frameshifting event (see McAdam et al., 1990). Start changed since first submission (+ 16 aa).
  
   
0.860
Rv2479c
Probable transposase; Rv2479c, (MTV008.35c), len: 328 aa. Probable transposase for IS6110. Identical to many other M. tuberculosis IS6110 transposase subunits. The transposase described here may be made by a frame shifting mechanism during translation that fuses Rv2480c and Rv2479c, the sequence UUUUAAAG (directly upstream of Rv2479c) maybe responsible for such a frameshifting event (see McAdam et al., 1990). Start changed since first submission (- 18 aa).
  
   
0.860
Rv2649
Rv2649, (MTCY441.18), len: 328 aa. Probable transposase for IS6110. Identical to many other M. tuberculosis IS6110 transposase subunits. The transposase described here may be made by a frame shifting mechanism during translation that fuses Rv2648 and Rv2649, the sequence UUUUAAAG (directly upstream of Rv2649) maybe responsible for such a frameshifting event (see McAdam et al., 1990).
  
   
0.860
Your Current Organism:
Mycobacterium tuberculosis H37Rv
NCBI taxonomy Id: 83332
Other names: M. tuberculosis H37Rv, Mycobacterium sp. H37Rv, Mycobacterium tuberculosis str. H37Rv, Mycobacterium tuberculosis strain H37Rv
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