Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Rv0547c | Rv3740c | Rv0547c | Rv3740c | Possible oxidoreductase; Rv0547c, (MTCY25D10.26c), len: 294 aa. Possible oxidoreductase, similar to various oxidoreductases e.g. fatty acyl-CoA reductase from Acinetobacter calcoaceticus (295 aa); NP_280196.1|NC_002607 3-oxoacyl-[acyl-carrier-protein] reductase from Halobacterium sp. NRC-1 (255 aa); NP_349214.1|NC_003030 Short-chain alcohol dehydrogenase family protein from Clostridium acetobutylicum (255 aa); etc. Also similar to several proteins from Mycobacterium tuberculosis e.g. Y04M_MYCTU|Q10783 putative oxidoreductase (341 aa), FASTA scores: opt: 644, E(): 0, (46.1% identity in [...] | Possible triacylglycerol synthase (diacylglycerol acyltransferase); Upon expression in E.coli has a weak triacylglycerol synthase function, making triacylglycerol (TG) from diolein and long-chain fatty acyl-CoA. Also functions weakly as a wax synthase, as it incorporates palmityl alcohol into wax esters in the presence of palmitoyl-CoA. | 0.669 |
| Rv0825c | Rv3740c | Rv0825c | Rv3740c | Conserved protein; Rv0825c, (MTV043.17c), len: 213 aa. Conserved protein, highly similar, but in part (between aa ~43-96) to fadD27|Rv0275c|MTV035.03 putative fatty-acid-CoA ligase from Mycobacterium tuberculosis (241 aa), FASTA scores: E(): 7.3e-09, (32.6% identity in 190 aa overlap). Also shows similarity with other proteins from Mycobacterium tuberculosis e.g. Rv0078|AL0214|MTV030_22 (201 aa), FASTA scores: opt:118, E(): 0.32, (34.5% identity in 113 aa overlap); etc. | Possible triacylglycerol synthase (diacylglycerol acyltransferase); Upon expression in E.coli has a weak triacylglycerol synthase function, making triacylglycerol (TG) from diolein and long-chain fatty acyl-CoA. Also functions weakly as a wax synthase, as it incorporates palmityl alcohol into wax esters in the presence of palmitoyl-CoA. | 0.600 |
| Rv0825c | acrA1 | Rv0825c | Rv3391 | Conserved protein; Rv0825c, (MTV043.17c), len: 213 aa. Conserved protein, highly similar, but in part (between aa ~43-96) to fadD27|Rv0275c|MTV035.03 putative fatty-acid-CoA ligase from Mycobacterium tuberculosis (241 aa), FASTA scores: E(): 7.3e-09, (32.6% identity in 190 aa overlap). Also shows similarity with other proteins from Mycobacterium tuberculosis e.g. Rv0078|AL0214|MTV030_22 (201 aa), FASTA scores: opt:118, E(): 0.32, (34.5% identity in 113 aa overlap); etc. | Rv3391, (MTV004.49), len: 650 aa. Possible acrA1,multi functional protein with fatty acyl-CoA reductase activity in C-terminal part. Indeed C-terminal part highly similar to P94129|ACR1 fatty acyl-CoA reductase from Acinetobacter calcoaceticus (295 aa), FASTA scores: opt: 767, E(): 1.4e-36, (45.4% identity in 260 aa overlap); and similar to other oxidoreductases dehydrogenases/reductases e.g. Q9Y3A1 CGI-93 protein (similarity with SDR family) from Homo sapiens (Human) (291 aa), FASTA scores: opt: 363,E(): 1.5e-13, (38.65% identity in 194 aa overlap); Q9L146|SC6D11.09 putative oxidoredu [...] | 0.467 |
| Rv1543 | Rv3740c | Rv1543 | Rv3740c | Rv1543, (MTCY48.22c), len: 341 aa. Possible fatty-acyl CoA reductase, highly similar to P94129|U77680 fatty acyl-CoA reductase ACR1 from Acinetobacter calcoaceticus (295 aa), FASTA scores: opt: 899, E(): 0,(48.5% identity in 293 aa overlap). Also highly similar to acrA1|Rv3391|MTV004.49|NP_217908.1|NC_000962 fatty acyl-CoA reductase from Mycobacterium tuberculosis (650 aa). Also highly similar to many oxidoreductases short-chain family; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Possible triacylglycerol synthase (diacylglycerol acyltransferase); Upon expression in E.coli has a weak triacylglycerol synthase function, making triacylglycerol (TG) from diolein and long-chain fatty acyl-CoA. Also functions weakly as a wax synthase, as it incorporates palmityl alcohol into wax esters in the presence of palmitoyl-CoA. | 0.728 |
| Rv1543 | pks2 | Rv1543 | Rv3825c | Rv1543, (MTCY48.22c), len: 341 aa. Possible fatty-acyl CoA reductase, highly similar to P94129|U77680 fatty acyl-CoA reductase ACR1 from Acinetobacter calcoaceticus (295 aa), FASTA scores: opt: 899, E(): 0,(48.5% identity in 293 aa overlap). Also highly similar to acrA1|Rv3391|MTV004.49|NP_217908.1|NC_000962 fatty acyl-CoA reductase from Mycobacterium tuberculosis (650 aa). Also highly similar to many oxidoreductases short-chain family; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Polyketide synthase Pks2; Catalyzes the synthesis of the hepta- and octamethyl phthioceranic acids and/or hydroxyphthioceranic acids that are the major acyl constituents of sulfolipids. | 0.412 |
| Rv2627c | Rv3740c | Rv2627c | Rv3740c | Conserved protein; Rv2627c, (MTCY01A10.05), len: 413 aa. Conserved protein. Some similarity in C-terminal part of O53697|Rv0293c|MTV035.21c hypothetical 44.0 KDA protein from Mycobacterium tuberculosis (400 aa), FASTA scores: opt: 392, E(): 1.9e-17, (31.1% identity in 299 aa overlap). Alternative nucleotide at position 2954439 (T->C; R104G) has been observed. Predicted possible vaccine candidate (See Zvi et al., 2008). | Possible triacylglycerol synthase (diacylglycerol acyltransferase); Upon expression in E.coli has a weak triacylglycerol synthase function, making triacylglycerol (TG) from diolein and long-chain fatty acyl-CoA. Also functions weakly as a wax synthase, as it incorporates palmityl alcohol into wax esters in the presence of palmitoyl-CoA. | 0.664 |
| Rv3740c | Rv0547c | Rv3740c | Rv0547c | Possible triacylglycerol synthase (diacylglycerol acyltransferase); Upon expression in E.coli has a weak triacylglycerol synthase function, making triacylglycerol (TG) from diolein and long-chain fatty acyl-CoA. Also functions weakly as a wax synthase, as it incorporates palmityl alcohol into wax esters in the presence of palmitoyl-CoA. | Possible oxidoreductase; Rv0547c, (MTCY25D10.26c), len: 294 aa. Possible oxidoreductase, similar to various oxidoreductases e.g. fatty acyl-CoA reductase from Acinetobacter calcoaceticus (295 aa); NP_280196.1|NC_002607 3-oxoacyl-[acyl-carrier-protein] reductase from Halobacterium sp. NRC-1 (255 aa); NP_349214.1|NC_003030 Short-chain alcohol dehydrogenase family protein from Clostridium acetobutylicum (255 aa); etc. Also similar to several proteins from Mycobacterium tuberculosis e.g. Y04M_MYCTU|Q10783 putative oxidoreductase (341 aa), FASTA scores: opt: 644, E(): 0, (46.1% identity in [...] | 0.669 |
| Rv3740c | Rv0825c | Rv3740c | Rv0825c | Possible triacylglycerol synthase (diacylglycerol acyltransferase); Upon expression in E.coli has a weak triacylglycerol synthase function, making triacylglycerol (TG) from diolein and long-chain fatty acyl-CoA. Also functions weakly as a wax synthase, as it incorporates palmityl alcohol into wax esters in the presence of palmitoyl-CoA. | Conserved protein; Rv0825c, (MTV043.17c), len: 213 aa. Conserved protein, highly similar, but in part (between aa ~43-96) to fadD27|Rv0275c|MTV035.03 putative fatty-acid-CoA ligase from Mycobacterium tuberculosis (241 aa), FASTA scores: E(): 7.3e-09, (32.6% identity in 190 aa overlap). Also shows similarity with other proteins from Mycobacterium tuberculosis e.g. Rv0078|AL0214|MTV030_22 (201 aa), FASTA scores: opt:118, E(): 0.32, (34.5% identity in 113 aa overlap); etc. | 0.600 |
| Rv3740c | Rv1543 | Rv3740c | Rv1543 | Possible triacylglycerol synthase (diacylglycerol acyltransferase); Upon expression in E.coli has a weak triacylglycerol synthase function, making triacylglycerol (TG) from diolein and long-chain fatty acyl-CoA. Also functions weakly as a wax synthase, as it incorporates palmityl alcohol into wax esters in the presence of palmitoyl-CoA. | Rv1543, (MTCY48.22c), len: 341 aa. Possible fatty-acyl CoA reductase, highly similar to P94129|U77680 fatty acyl-CoA reductase ACR1 from Acinetobacter calcoaceticus (295 aa), FASTA scores: opt: 899, E(): 0,(48.5% identity in 293 aa overlap). Also highly similar to acrA1|Rv3391|MTV004.49|NP_217908.1|NC_000962 fatty acyl-CoA reductase from Mycobacterium tuberculosis (650 aa). Also highly similar to many oxidoreductases short-chain family; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.728 |
| Rv3740c | Rv2627c | Rv3740c | Rv2627c | Possible triacylglycerol synthase (diacylglycerol acyltransferase); Upon expression in E.coli has a weak triacylglycerol synthase function, making triacylglycerol (TG) from diolein and long-chain fatty acyl-CoA. Also functions weakly as a wax synthase, as it incorporates palmityl alcohol into wax esters in the presence of palmitoyl-CoA. | Conserved protein; Rv2627c, (MTCY01A10.05), len: 413 aa. Conserved protein. Some similarity in C-terminal part of O53697|Rv0293c|MTV035.21c hypothetical 44.0 KDA protein from Mycobacterium tuberculosis (400 aa), FASTA scores: opt: 392, E(): 1.9e-17, (31.1% identity in 299 aa overlap). Alternative nucleotide at position 2954439 (T->C; R104G) has been observed. Predicted possible vaccine candidate (See Zvi et al., 2008). | 0.664 |
| Rv3740c | Rv3741c | Rv3740c | Rv3741c | Possible triacylglycerol synthase (diacylglycerol acyltransferase); Upon expression in E.coli has a weak triacylglycerol synthase function, making triacylglycerol (TG) from diolein and long-chain fatty acyl-CoA. Also functions weakly as a wax synthase, as it incorporates palmityl alcohol into wax esters in the presence of palmitoyl-CoA. | Rv3741c, (MTV025.089c), len: 224 aa. Possible oxidoreductase, probably combines with product of upstream ORF MTV025.090c to form a functional monooxygenase, highly similar to C-terminal end of various oxidoreductases e.g. Q9APW3 aromatic-ring hyroxylase from Pseudomonas aeruginosa (508 aa), FASTA scores: opt: 549, E(): 5.9e-28, (56.1% identity in 155 aa overlap); Q9A588|CC2569 monooxygenase (flavin-binding family) from Caulobacter crescentus (498 aa), FASTA scores: opt: 487, E(): 5.6e-24, (39.55% identity in 225 aa overlap); Q9RZT0|DRB0033 arylesterase/monoxygenase from Deinococcus rad [...] | 0.980 |
| Rv3740c | Rv3742c | Rv3740c | Rv3742c | Possible triacylglycerol synthase (diacylglycerol acyltransferase); Upon expression in E.coli has a weak triacylglycerol synthase function, making triacylglycerol (TG) from diolein and long-chain fatty acyl-CoA. Also functions weakly as a wax synthase, as it incorporates palmityl alcohol into wax esters in the presence of palmitoyl-CoA. | Rv3742c, (MTV025.090c), len: 131 aa. Possible oxidoreductase, probably combines with product of downstream ORF MTV025.090c to form a functional monooxygenase, highly similar to N-terminal end of various oxidoreductases e.g. Q9A588|CC2569 monooxygenase (flavin-binding family) from Caulobacter crescentus (498 aa), FASTA scores: opt: 170, E(): 0.00048, (47.55% identity in 103 aa overlap); Q9APW3 aromatic-ring hyroxylase from Pseudomonas aeruginosa (508 aa) FASTA scores: opt: 160,E(): 0.0022, (50.55% identity in 87 aa overlap); Q9RZT0|DRB0033 arylesterase/monoxygenase from Deinococcus radi [...] | 0.978 |
| Rv3740c | acrA1 | Rv3740c | Rv3391 | Possible triacylglycerol synthase (diacylglycerol acyltransferase); Upon expression in E.coli has a weak triacylglycerol synthase function, making triacylglycerol (TG) from diolein and long-chain fatty acyl-CoA. Also functions weakly as a wax synthase, as it incorporates palmityl alcohol into wax esters in the presence of palmitoyl-CoA. | Rv3391, (MTV004.49), len: 650 aa. Possible acrA1,multi functional protein with fatty acyl-CoA reductase activity in C-terminal part. Indeed C-terminal part highly similar to P94129|ACR1 fatty acyl-CoA reductase from Acinetobacter calcoaceticus (295 aa), FASTA scores: opt: 767, E(): 1.4e-36, (45.4% identity in 260 aa overlap); and similar to other oxidoreductases dehydrogenases/reductases e.g. Q9Y3A1 CGI-93 protein (similarity with SDR family) from Homo sapiens (Human) (291 aa), FASTA scores: opt: 363,E(): 1.5e-13, (38.65% identity in 194 aa overlap); Q9L146|SC6D11.09 putative oxidoredu [...] | 0.771 |
| Rv3740c | dagK | Rv3740c | Rv2252 | Possible triacylglycerol synthase (diacylglycerol acyltransferase); Upon expression in E.coli has a weak triacylglycerol synthase function, making triacylglycerol (TG) from diolein and long-chain fatty acyl-CoA. Also functions weakly as a wax synthase, as it incorporates palmityl alcohol into wax esters in the presence of palmitoyl-CoA. | Diacylglycerol kinase; Catalyzes the phosphorylation of diacylglycerol (DAG) into phosphatidic acid. Is involved in the biosynthesis of phosphatidylinositol mannosides (PIMs), probably via a role in the biosynthesis of phosphatidylinositol (PI), a PIM precursor, which is derived from phosphatidic acid (By similarity); Belongs to the diacylglycerol/lipid kinase family. | 0.900 |
| Rv3740c | lipY | Rv3740c | Rv3097c | Possible triacylglycerol synthase (diacylglycerol acyltransferase); Upon expression in E.coli has a weak triacylglycerol synthase function, making triacylglycerol (TG) from diolein and long-chain fatty acyl-CoA. Also functions weakly as a wax synthase, as it incorporates palmityl alcohol into wax esters in the presence of palmitoyl-CoA. | Triacylglycerol lipase; Responsible for the utilization of stored long-chain triacylglycerol (TG) during dormancy and reactivation stage of the infection cycle. Catalyzes the hydrolysis of long-chain triacylglycerol with high specific activity; In the C-terminal section; belongs to the 'GDXG' lipolytic enzyme family. | 0.919 |
| Rv3740c | pks2 | Rv3740c | Rv3825c | Possible triacylglycerol synthase (diacylglycerol acyltransferase); Upon expression in E.coli has a weak triacylglycerol synthase function, making triacylglycerol (TG) from diolein and long-chain fatty acyl-CoA. Also functions weakly as a wax synthase, as it incorporates palmityl alcohol into wax esters in the presence of palmitoyl-CoA. | Polyketide synthase Pks2; Catalyzes the synthesis of the hepta- and octamethyl phthioceranic acids and/or hydroxyphthioceranic acids that are the major acyl constituents of sulfolipids. | 0.533 |
| Rv3741c | Rv3740c | Rv3741c | Rv3740c | Rv3741c, (MTV025.089c), len: 224 aa. Possible oxidoreductase, probably combines with product of upstream ORF MTV025.090c to form a functional monooxygenase, highly similar to C-terminal end of various oxidoreductases e.g. Q9APW3 aromatic-ring hyroxylase from Pseudomonas aeruginosa (508 aa), FASTA scores: opt: 549, E(): 5.9e-28, (56.1% identity in 155 aa overlap); Q9A588|CC2569 monooxygenase (flavin-binding family) from Caulobacter crescentus (498 aa), FASTA scores: opt: 487, E(): 5.6e-24, (39.55% identity in 225 aa overlap); Q9RZT0|DRB0033 arylesterase/monoxygenase from Deinococcus rad [...] | Possible triacylglycerol synthase (diacylglycerol acyltransferase); Upon expression in E.coli has a weak triacylglycerol synthase function, making triacylglycerol (TG) from diolein and long-chain fatty acyl-CoA. Also functions weakly as a wax synthase, as it incorporates palmityl alcohol into wax esters in the presence of palmitoyl-CoA. | 0.980 |
| Rv3741c | Rv3742c | Rv3741c | Rv3742c | Rv3741c, (MTV025.089c), len: 224 aa. Possible oxidoreductase, probably combines with product of upstream ORF MTV025.090c to form a functional monooxygenase, highly similar to C-terminal end of various oxidoreductases e.g. Q9APW3 aromatic-ring hyroxylase from Pseudomonas aeruginosa (508 aa), FASTA scores: opt: 549, E(): 5.9e-28, (56.1% identity in 155 aa overlap); Q9A588|CC2569 monooxygenase (flavin-binding family) from Caulobacter crescentus (498 aa), FASTA scores: opt: 487, E(): 5.6e-24, (39.55% identity in 225 aa overlap); Q9RZT0|DRB0033 arylesterase/monoxygenase from Deinococcus rad [...] | Rv3742c, (MTV025.090c), len: 131 aa. Possible oxidoreductase, probably combines with product of downstream ORF MTV025.090c to form a functional monooxygenase, highly similar to N-terminal end of various oxidoreductases e.g. Q9A588|CC2569 monooxygenase (flavin-binding family) from Caulobacter crescentus (498 aa), FASTA scores: opt: 170, E(): 0.00048, (47.55% identity in 103 aa overlap); Q9APW3 aromatic-ring hyroxylase from Pseudomonas aeruginosa (508 aa) FASTA scores: opt: 160,E(): 0.0022, (50.55% identity in 87 aa overlap); Q9RZT0|DRB0033 arylesterase/monoxygenase from Deinococcus radi [...] | 0.996 |
| Rv3742c | Rv3740c | Rv3742c | Rv3740c | Rv3742c, (MTV025.090c), len: 131 aa. Possible oxidoreductase, probably combines with product of downstream ORF MTV025.090c to form a functional monooxygenase, highly similar to N-terminal end of various oxidoreductases e.g. Q9A588|CC2569 monooxygenase (flavin-binding family) from Caulobacter crescentus (498 aa), FASTA scores: opt: 170, E(): 0.00048, (47.55% identity in 103 aa overlap); Q9APW3 aromatic-ring hyroxylase from Pseudomonas aeruginosa (508 aa) FASTA scores: opt: 160,E(): 0.0022, (50.55% identity in 87 aa overlap); Q9RZT0|DRB0033 arylesterase/monoxygenase from Deinococcus radi [...] | Possible triacylglycerol synthase (diacylglycerol acyltransferase); Upon expression in E.coli has a weak triacylglycerol synthase function, making triacylglycerol (TG) from diolein and long-chain fatty acyl-CoA. Also functions weakly as a wax synthase, as it incorporates palmityl alcohol into wax esters in the presence of palmitoyl-CoA. | 0.978 |
| Rv3742c | Rv3741c | Rv3742c | Rv3741c | Rv3742c, (MTV025.090c), len: 131 aa. Possible oxidoreductase, probably combines with product of downstream ORF MTV025.090c to form a functional monooxygenase, highly similar to N-terminal end of various oxidoreductases e.g. Q9A588|CC2569 monooxygenase (flavin-binding family) from Caulobacter crescentus (498 aa), FASTA scores: opt: 170, E(): 0.00048, (47.55% identity in 103 aa overlap); Q9APW3 aromatic-ring hyroxylase from Pseudomonas aeruginosa (508 aa) FASTA scores: opt: 160,E(): 0.0022, (50.55% identity in 87 aa overlap); Q9RZT0|DRB0033 arylesterase/monoxygenase from Deinococcus radi [...] | Rv3741c, (MTV025.089c), len: 224 aa. Possible oxidoreductase, probably combines with product of upstream ORF MTV025.090c to form a functional monooxygenase, highly similar to C-terminal end of various oxidoreductases e.g. Q9APW3 aromatic-ring hyroxylase from Pseudomonas aeruginosa (508 aa), FASTA scores: opt: 549, E(): 5.9e-28, (56.1% identity in 155 aa overlap); Q9A588|CC2569 monooxygenase (flavin-binding family) from Caulobacter crescentus (498 aa), FASTA scores: opt: 487, E(): 5.6e-24, (39.55% identity in 225 aa overlap); Q9RZT0|DRB0033 arylesterase/monoxygenase from Deinococcus rad [...] | 0.996 |
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