node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
add | apt | b1623 | b0469 | Adenosine deaminase; Protein involved in nucleobase, nucleoside and nucleotide interconversion; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.871 |
add | cdd | b1623 | b2143 | Adenosine deaminase; Protein involved in nucleobase, nucleoside and nucleotide interconversion; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. | Cytidine/deoxycytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | 0.714 |
add | deoA | b1623 | b4382 | Adenosine deaminase; Protein involved in nucleobase, nucleoside and nucleotide interconversion; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis; Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.443 |
add | deoD | b1623 | b4384 | Adenosine deaminase; Protein involved in nucleobase, nucleoside and nucleotide interconversion; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. | Purine nucleoside phosphorylase 1; Cleavage of guanosine or inosine to respective bases and sugar-1-phosphate molecules. | 0.980 |
add | gsk | b1623 | b0477 | Adenosine deaminase; Protein involved in nucleobase, nucleoside and nucleotide interconversion; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. | Inosine-guanosine kinase; Protein involved in nucleobase, nucleoside and nucleotide interconversion. | 0.971 |
add | xapA | b1623 | b2407 | Adenosine deaminase; Protein involved in nucleobase, nucleoside and nucleotide interconversion; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. | Purine nucleoside phosphorylase 2; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. This protein can degrade all purine nucleosides including xanthosine, inosine and guanosine, but cannot cleave adenosine, deoxyadenosine or hypoxanthine arabinoside. Has a preference for the neutral over the monoanionic form of xanthosine. | 0.723 |
add | yaiE | b1623 | b0391 | Adenosine deaminase; Protein involved in nucleobase, nucleoside and nucleotide interconversion; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. | UPF0345 family protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. Is not able to produce D-ribose 1-phosphate from D-ribose and phosphate. | 0.948 |
apt | add | b0469 | b1623 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Adenosine deaminase; Protein involved in nucleobase, nucleoside and nucleotide interconversion; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. | 0.871 |
apt | cdd | b0469 | b2143 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Cytidine/deoxycytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | 0.434 |
apt | deoA | b0469 | b4382 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis; Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.490 |
apt | deoD | b0469 | b4384 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Purine nucleoside phosphorylase 1; Cleavage of guanosine or inosine to respective bases and sugar-1-phosphate molecules. | 0.980 |
apt | gsk | b0469 | b0477 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Inosine-guanosine kinase; Protein involved in nucleobase, nucleoside and nucleotide interconversion. | 0.937 |
apt | udk | b0469 | b2066 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Uridine/cytidine kinase; Protein involved in nucleobase, nucleoside and nucleotide interconversion; Belongs to the uridine kinase family. | 0.444 |
apt | udp | b0469 | b3831 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. | 0.415 |
apt | yaiE | b0469 | b0391 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | UPF0345 family protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. Is not able to produce D-ribose 1-phosphate from D-ribose and phosphate. | 0.929 |
cdd | add | b2143 | b1623 | Cytidine/deoxycytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | Adenosine deaminase; Protein involved in nucleobase, nucleoside and nucleotide interconversion; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. | 0.714 |
cdd | apt | b2143 | b0469 | Cytidine/deoxycytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.434 |
cdd | deoA | b2143 | b4382 | Cytidine/deoxycytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis; Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.986 |
cdd | deoD | b2143 | b4384 | Cytidine/deoxycytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | Purine nucleoside phosphorylase 1; Cleavage of guanosine or inosine to respective bases and sugar-1-phosphate molecules. | 0.949 |
cdd | gsk | b2143 | b0477 | Cytidine/deoxycytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | Inosine-guanosine kinase; Protein involved in nucleobase, nucleoside and nucleotide interconversion. | 0.658 |