node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
arcA | insQ | b4401 | b1432 | Response regulator in two-component regulatory system with ArcB or CpxA; Member of the two-component regulatory system ArcB/ArcA. Represses a wide variety of aerobic enzymes under anaerobic conditions. Controls the resistance of E.coli to dyes; required for expression of the alkaline phosphatase and sex factor F genes; It also may be involved in the osmoregulation of envelope proteins. When activated by ArcB, it negatively regulates the expression of genes of aerobic function. Activates the transcription of the plfB operon by binding to its promoter. | Putative transposase InsQ for insertion sequence element IS609; Required for the transposition of the insertion element. In the C-terminal section; belongs to the transposase 35 family. | 0.529 |
casC | insQ | b2758 | b1432 | CRISP RNA (crRNA) containing Cascade antiviral complex protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). | Putative transposase InsQ for insertion sequence element IS609; Required for the transposition of the insertion element. In the C-terminal section; belongs to the transposase 35 family. | 0.408 |
casC | ruvC | b2758 | b1863 | CRISP RNA (crRNA) containing Cascade antiviral complex protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). | Component of RuvABC resolvasome, endonuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.809 |
casC | ygbF | b2758 | b2754 | CRISP RNA (crRNA) containing Cascade antiviral complex protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). | CRISPR adaptation ssRNA endonuclease; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). The Cas1-Cas2 complex is involved in CRISPR adaptation, the first stage of CRISPR immunity, being required for the addition/removal of CRISPR spacers at the l [...] | 0.999 |
chpS | insQ | b4224 | b1432 | Antitoxin of the ChpBS toxin-antitoxin system; Antitoxin component of a type II toxin-antitoxin (TA) system. May be involved in the regulation of cell growth. It acts as a suppressor of the endoribonuclease (inhibitory function) of ChpB protein. Both ChpS and ChpB probably bind to the promoter region of the chpS-chpB operon to autoregulate their synthesis. | Putative transposase InsQ for insertion sequence element IS609; Required for the transposition of the insertion element. In the C-terminal section; belongs to the transposase 35 family. | 0.520 |
insQ | arcA | b1432 | b4401 | Putative transposase InsQ for insertion sequence element IS609; Required for the transposition of the insertion element. In the C-terminal section; belongs to the transposase 35 family. | Response regulator in two-component regulatory system with ArcB or CpxA; Member of the two-component regulatory system ArcB/ArcA. Represses a wide variety of aerobic enzymes under anaerobic conditions. Controls the resistance of E.coli to dyes; required for expression of the alkaline phosphatase and sex factor F genes; It also may be involved in the osmoregulation of envelope proteins. When activated by ArcB, it negatively regulates the expression of genes of aerobic function. Activates the transcription of the plfB operon by binding to its promoter. | 0.529 |
insQ | casC | b1432 | b2758 | Putative transposase InsQ for insertion sequence element IS609; Required for the transposition of the insertion element. In the C-terminal section; belongs to the transposase 35 family. | CRISP RNA (crRNA) containing Cascade antiviral complex protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). | 0.408 |
insQ | chpS | b1432 | b4224 | Putative transposase InsQ for insertion sequence element IS609; Required for the transposition of the insertion element. In the C-terminal section; belongs to the transposase 35 family. | Antitoxin of the ChpBS toxin-antitoxin system; Antitoxin component of a type II toxin-antitoxin (TA) system. May be involved in the regulation of cell growth. It acts as a suppressor of the endoribonuclease (inhibitory function) of ChpB protein. Both ChpS and ChpB probably bind to the promoter region of the chpS-chpB operon to autoregulate their synthesis. | 0.520 |
insQ | ruvC | b1432 | b1863 | Putative transposase InsQ for insertion sequence element IS609; Required for the transposition of the insertion element. In the C-terminal section; belongs to the transposase 35 family. | Component of RuvABC resolvasome, endonuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.876 |
insQ | ves | b1432 | b1742 | Putative transposase InsQ for insertion sequence element IS609; Required for the transposition of the insertion element. In the C-terminal section; belongs to the transposase 35 family. | Cold- and stress-inducible protein; Belongs to the Ves family. | 0.503 |
insQ | ybdN | b1432 | b0602 | Putative transposase InsQ for insertion sequence element IS609; Required for the transposition of the insertion element. In the C-terminal section; belongs to the transposase 35 family. | PAPS reductase-like domain protein. | 0.493 |
insQ | ybhI | b1432 | b0770 | Putative transposase InsQ for insertion sequence element IS609; Required for the transposition of the insertion element. In the C-terminal section; belongs to the transposase 35 family. | Putative DASS family tricarboxylate or dicarboxylate transporter; Putative membrane pump protein. | 0.462 |
insQ | yebW | b1432 | b1837 | Putative transposase InsQ for insertion sequence element IS609; Required for the transposition of the insertion element. In the C-terminal section; belongs to the transposase 35 family. | Uncharacterized protein. | 0.642 |
insQ | ygbF | b1432 | b2754 | Putative transposase InsQ for insertion sequence element IS609; Required for the transposition of the insertion element. In the C-terminal section; belongs to the transposase 35 family. | CRISPR adaptation ssRNA endonuclease; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). The Cas1-Cas2 complex is involved in CRISPR adaptation, the first stage of CRISPR immunity, being required for the addition/removal of CRISPR spacers at the l [...] | 0.586 |
insQ | yraQ | b1432 | b3151 | Putative transposase InsQ for insertion sequence element IS609; Required for the transposition of the insertion element. In the C-terminal section; belongs to the transposase 35 family. | Putative inner membrane permease. | 0.781 |
ruvC | casC | b1863 | b2758 | Component of RuvABC resolvasome, endonuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | CRISP RNA (crRNA) containing Cascade antiviral complex protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). | 0.809 |
ruvC | insQ | b1863 | b1432 | Component of RuvABC resolvasome, endonuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | Putative transposase InsQ for insertion sequence element IS609; Required for the transposition of the insertion element. In the C-terminal section; belongs to the transposase 35 family. | 0.876 |
ruvC | ygbF | b1863 | b2754 | Component of RuvABC resolvasome, endonuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | CRISPR adaptation ssRNA endonuclease; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). The Cas1-Cas2 complex is involved in CRISPR adaptation, the first stage of CRISPR immunity, being required for the addition/removal of CRISPR spacers at the l [...] | 0.805 |
ves | insQ | b1742 | b1432 | Cold- and stress-inducible protein; Belongs to the Ves family. | Putative transposase InsQ for insertion sequence element IS609; Required for the transposition of the insertion element. In the C-terminal section; belongs to the transposase 35 family. | 0.503 |
ybdN | insQ | b0602 | b1432 | PAPS reductase-like domain protein. | Putative transposase InsQ for insertion sequence element IS609; Required for the transposition of the insertion element. In the C-terminal section; belongs to the transposase 35 family. | 0.493 |