STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppdBPutative prepilin peptidase-dependent protein; Not yet known. (187 aa)    
Predicted Functional Partners:
ppdA
Putative prepilin peptidase-dependent protein; Not yet known.
  
 
 0.996
ppdC
Putative prepilin peptidase-dependent protein; Not yet known.
  
  
 0.951
ygdB
DUF2509 family protein.
  
  
 0.918
recC
Exonuclease V (RecBCD complex), gamma chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a rapid (>1 kb/second) and highly processive (>30 kb) ATP-dependent bidirectional helicase. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator, 5'-GCTGGTGG-3') sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to Chi site, by nicking one strand or switching the strand degraded (depending on the reaction conditions). The properties and activities of the enzyme are changed at Chi. The Chi-alter [...]
       0.762
gspK
General secretory pathway component, cryptic; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. Belongs to the GSP K family.
  
 
 0.752
ppdD
Putative prepilin peptidase-dependent pilin; Not yet known; Belongs to the N-Me-Phe pilin family.
   
  
 0.734
sgcB
Putative enzyme IIB component of PTS; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.
      
 0.624
hofC
Assembly protein in type IV pilin biogenesis, transmembrane protein; Putative integral membrane protein involved in biogenesis of fimbriae, protein transport, DNA uptake.
  
  
 0.615
hofB
T2SE secretion family protein; Putative integral membrane protein involved in biogenesis of fimbriae, protein transport, DNA uptake; Belongs to the GSP E family.
     
 0.591
yfdN
Uncharacterized protein YfdN; CPS-53 (KpLE1) prophage; putative methyltransferase;Phage or Prophage Related.
   
  
 0.573
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.