node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
katE | osmC | b1732 | b1482 | Catalase HPII, heme d-containing; Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. | Lipoyl-dependent Cys-based peroxidase, hydroperoxide resistance; Preferentially metabolizes organic hydroperoxides over inorganic hydrogen peroxide; Belongs to the OsmC/Ohr family. | 0.906 |
katE | osmE | b1732 | b1739 | Catalase HPII, heme d-containing; Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. | Osmotically-inducible lipoprotein; Activator of ntrL gene; Protein involved in transcription activator activity, transcription and response to osmotic stress. | 0.527 |
katE | osmY | b1732 | b4376 | Catalase HPII, heme d-containing; Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. | Salt-inducible putative ABC transporter periplasmic binding protein; Hyperosmotically inducible periplasmic protein; Protein involved in response to osmotic stress. | 0.871 |
katE | otsA | b1732 | b1896 | Catalase HPII, heme d-containing; Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. | Trehalose-6-phosphate synthase; Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6- phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor. Essential for viability of the cells at low temperatures and at elevated osmotic strength. Belongs to the glycosyltransferase 20 family. | 0.900 |
katE | rpoS | b1732 | b2741 | Catalase HPII, heme d-containing; Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. | RNA polymerase, sigma S (sigma 38) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. Controls, positively or negatively, the expression of several hundred genes, which are mainly involved in metabolism, transport, regulation and stress management. | 0.905 |
katE | ybaY | b1732 | b0453 | Catalase HPII, heme d-containing; Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. | Outer membrane lipoprotein; Glycoprotein/polysaccharide metabolism; Protein involved in lipoprotein biosynthetic process and glycoprotein biosynthetic process. | 0.461 |
katE | ygaU | b1732 | b2665 | Catalase HPII, heme d-containing; Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. | Uncharacterized protein; Highly specific potassium binding protein that is required for normal growth in the presence of high levels of external K(+). May act as a sensor of cytoplasmic K(+) concentration. Binds a single K(+) ion, which induces a large conformational change. Can also bind the larger alkali metal ions Rb(+) and Cs(+), and NH(4)(+). May be involved in the regulation of peptidoglycan cross-linking. | 0.524 |
katE | yjbJ | b1732 | b4045 | Catalase HPII, heme d-containing; Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. | Stress-induced protein, UPF0337 family; Belongs to the UPF0337 (CsbD) family. | 0.571 |
katE | yqjD | b1732 | b3098 | Catalase HPII, heme d-containing; Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. | Membrane-anchored ribosome-binding protein; Upon overexpression inhibits growth. | 0.418 |
osmC | katE | b1482 | b1732 | Lipoyl-dependent Cys-based peroxidase, hydroperoxide resistance; Preferentially metabolizes organic hydroperoxides over inorganic hydrogen peroxide; Belongs to the OsmC/Ohr family. | Catalase HPII, heme d-containing; Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. | 0.906 |
osmC | osmE | b1482 | b1739 | Lipoyl-dependent Cys-based peroxidase, hydroperoxide resistance; Preferentially metabolizes organic hydroperoxides over inorganic hydrogen peroxide; Belongs to the OsmC/Ohr family. | Osmotically-inducible lipoprotein; Activator of ntrL gene; Protein involved in transcription activator activity, transcription and response to osmotic stress. | 0.899 |
osmC | osmY | b1482 | b4376 | Lipoyl-dependent Cys-based peroxidase, hydroperoxide resistance; Preferentially metabolizes organic hydroperoxides over inorganic hydrogen peroxide; Belongs to the OsmC/Ohr family. | Salt-inducible putative ABC transporter periplasmic binding protein; Hyperosmotically inducible periplasmic protein; Protein involved in response to osmotic stress. | 0.905 |
osmC | otsA | b1482 | b1896 | Lipoyl-dependent Cys-based peroxidase, hydroperoxide resistance; Preferentially metabolizes organic hydroperoxides over inorganic hydrogen peroxide; Belongs to the OsmC/Ohr family. | Trehalose-6-phosphate synthase; Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6- phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor. Essential for viability of the cells at low temperatures and at elevated osmotic strength. Belongs to the glycosyltransferase 20 family. | 0.781 |
osmC | rpoS | b1482 | b2741 | Lipoyl-dependent Cys-based peroxidase, hydroperoxide resistance; Preferentially metabolizes organic hydroperoxides over inorganic hydrogen peroxide; Belongs to the OsmC/Ohr family. | RNA polymerase, sigma S (sigma 38) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. Controls, positively or negatively, the expression of several hundred genes, which are mainly involved in metabolism, transport, regulation and stress management. | 0.683 |
osmC | ybaY | b1482 | b0453 | Lipoyl-dependent Cys-based peroxidase, hydroperoxide resistance; Preferentially metabolizes organic hydroperoxides over inorganic hydrogen peroxide; Belongs to the OsmC/Ohr family. | Outer membrane lipoprotein; Glycoprotein/polysaccharide metabolism; Protein involved in lipoprotein biosynthetic process and glycoprotein biosynthetic process. | 0.750 |
osmC | ygaU | b1482 | b2665 | Lipoyl-dependent Cys-based peroxidase, hydroperoxide resistance; Preferentially metabolizes organic hydroperoxides over inorganic hydrogen peroxide; Belongs to the OsmC/Ohr family. | Uncharacterized protein; Highly specific potassium binding protein that is required for normal growth in the presence of high levels of external K(+). May act as a sensor of cytoplasmic K(+) concentration. Binds a single K(+) ion, which induces a large conformational change. Can also bind the larger alkali metal ions Rb(+) and Cs(+), and NH(4)(+). May be involved in the regulation of peptidoglycan cross-linking. | 0.855 |
osmC | yjbJ | b1482 | b4045 | Lipoyl-dependent Cys-based peroxidase, hydroperoxide resistance; Preferentially metabolizes organic hydroperoxides over inorganic hydrogen peroxide; Belongs to the OsmC/Ohr family. | Stress-induced protein, UPF0337 family; Belongs to the UPF0337 (CsbD) family. | 0.708 |
osmC | yqjD | b1482 | b3098 | Lipoyl-dependent Cys-based peroxidase, hydroperoxide resistance; Preferentially metabolizes organic hydroperoxides over inorganic hydrogen peroxide; Belongs to the OsmC/Ohr family. | Membrane-anchored ribosome-binding protein; Upon overexpression inhibits growth. | 0.802 |
osmE | katE | b1739 | b1732 | Osmotically-inducible lipoprotein; Activator of ntrL gene; Protein involved in transcription activator activity, transcription and response to osmotic stress. | Catalase HPII, heme d-containing; Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. | 0.527 |
osmE | osmC | b1739 | b1482 | Osmotically-inducible lipoprotein; Activator of ntrL gene; Protein involved in transcription activator activity, transcription and response to osmotic stress. | Lipoyl-dependent Cys-based peroxidase, hydroperoxide resistance; Preferentially metabolizes organic hydroperoxides over inorganic hydrogen peroxide; Belongs to the OsmC/Ohr family. | 0.899 |