STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
slyATranscriptional regulator for cryptic hemolysin; Transcription regulator that can specifically activate or repress expression of target genes; Belongs to the SlyA family. (146 aa)    
Predicted Functional Partners:
marR
Multiple antibiotic resistance protein; Residues 1 to 125 of 125 are 98.40 pct identical to residues 1 to 125 of 125 from Escherichia coli K-12 Strain MG1655: B1530.
  
   
 0.841
hlyE
Putative pore forming hemolysin; Toxin, which has some hemolytic activity towards mammalian cells. Acts by forming a pore-like structure upon contact with mammalian cells (By similarity); Belongs to the hemolysin E family.
      
 0.764
edcC
Orf; Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. Phenolic acid decarboxylase that catalyzes the reversible decarboxylation of 4-hydroxybenzoate and vanillate. Belongs to the UbiD family. YclC subfamily.
      
 0.721
ecdB
Putative decarboxylase; Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for phenolic acid decarboxylase (By similarity); Belongs to the UbiX/PAD1 family. YclB subfamily.
      
 0.721
fhlA
Formate hydrogen-lyase transcriptional activator for fdhF, hyc and hyp operons; Residues 1 to 692 of 692 are 99.56 pct identical to residues 1 to 692 of 692 from Escherichia coli K-12 Strain MG1655: B2731.
      
 0.715
pqiA
Paraquat-inducible protein A; Residues 1 to 417 of 417 are 99.76 pct identical to residues 1 to 417 of 417 from Escherichia coli K-12 Strain MG1655: B0950.
      
 0.700
phoP
Transcriptional regulatory protein; Member of the two-component regulatory system PhoQ/PhoP involved in virulence, adaptation to low Mg(2+) environments and the control of acid resistance genes.
   
  
 0.629
ydhI
Orf, hypothetical protein; Residues 1 to 78 of 78 are 100.00 pct identical to residues 1 to 78 of 78 from Escherichia coli K-12 Strain MG1655: B1643.
  
  
 0.601
ydhJ
Putative membrane protein; Residues 1 to 299 of 299 are 99.66 pct identical to residues 1 to 299 of 299 from Escherichia coli K-12 Strain MG1655: B1644; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
  
 0.597
himA
Integration host factor (IHF), alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.
   
  
 0.567
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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