STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECs04052-keto-4-pentenoate hydratase; Similar to MHPD_ECOLI gi|1786546 percent identity 98 in 269 aa but differs at N-ter. (269 aa)    
Predicted Functional Partners:
ECs0404
2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase; Similar to MHPC_ECOLI gi|1786545 percent identity 99 in 308 aa (Conserved in E.coli K-12).
 
 
 0.998
ECs0407
4-hydroxy-2-ketovalerate aldolase; Similar to MHPE_ECOLI gi|1786548 percent identity 99 in 337 aa (Conserved in E.coli K-12).
 
 
 0.998
ECs0406
Acetaldehyde dehydrogenase; Similar to MHPF_ECOLI gi|1786547 percent identity 99 in 316 aa (Conserved in E.coli K-12).
 
  
 0.984
ECs0403
2,3-dihydroxyphenylpropionate 1,2-dioxygenase; Identical to MHPB_ECOLI gi|1786544 (Conserved in E.coli K-12).
 
  
 0.963
ECs0402
3-(3-hydroxyphenyl)propionate hydroxylase; Similar to MHPA_ECOLI gi|1786543 percent identity 99 in 554 aa (Conserved in E.coli K-12).
 
  
 0.922
ECs0401
Transcriptional regulator for mhp operon; Similar to MHPR_ECOLI gi|1786541 percent identity 98 in 315 aa (Conserved in E.coli K-12).
 
  
 0.828
ECs3405
Phenylpropionate dioxygenase small terminal subunit; Similar to HCAA2_ECOLI gi|1788889 percent identity 99 in 172 aa (Conserved in E.coli K-12).
 
   
 0.786
ECs3404
Phenylpropionate dioxygenase large terminal subunit; Similar to HCAA1_ECOLI gi|1788888 percent identity 100 in 453 aa (Conserved in E.coli K-12).
 
   
 0.783
ECs3130
Hypothetical protein; Similar to B2245_ECOLI gi|1788578 percent identity 98 in 250 aa but differs at N-ter, GTG start (Conserved in E.coli K-12).
 
  
 0.742
ECs4004
Hypothetical protein; Similar to YHAF_ECOLI gi|1789514 percent identity 99 in 256 aa (Conserved in E.coli K-12).
 
  
 0.713
Your Current Organism:
Escherichia coli O157H7 Sakai
NCBI taxonomy Id: 386585
Other names: E. coli O157:H7 str. Sakai, Escherichia coli O157:H7 str. Sakai, Escherichia coli O157:H7 strain Sakai
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.