STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECs4109Malate dehydrogenase; Similar to MDH_ECOLI gi|1789632 percent identity 100 in 312 aa (Conserved in E.coli K-12). (312 aa)    
Predicted Functional Partners:
ECs2317
Similar to FUMC_ECOLI gi|1787896 percent identity 99 in 467 aa (Conserved in E.coli K-12).
  
 0.995
ECs0745
Citrate synthase; Similar to GLTA_ECOLI gi|1786939 percent identity 99 in 426 aa (Conserved in E.coli K-12).
  
 0.988
ECs2000
Putative oxidoreductase; Similar to YDBK_ECOLI gi|1787642 percent identity 99 in 1174 aa (Conserved in E.coli K-12).
  
 
 0.988
ECs2318
Similar to FUMA_ECOLI gi|1787897 percent identity 99 in 548 aa, similar to FUMB_ECOLI gi|1790564 percent identity 89 in 548 aa (Conserved in E.coli K-12).
  
 
 0.988
ECs0757
Probable fumarate hydratase,similar to fumarate hydratases e.g. fumarate hydratase class I, aerobic (fumarase) - Escherichia coli gi|120598|sp|P00923|FUMA_ECOLI percent identity 68 in 545 aa.
  
 
 0.979
ECs5104
Fumarase B; Similar to FUMA_ECOLI gi|1787897 percent identity 89 in 548 aa, similar to FUMB_ECOLI gi|1790564 percent identity 99 in 548 aa (Conserved in E.coli K-12).
  
 
 0.979
ECs1608
Isocitrate dehydrogenase; Similar to ICDA_ECOLI gi|1787381 percent identity 99 in 416 aa (Conserved in E.coli K-12).
  
 
 0.970
ECs1011
Aspartate aminotransferase; Similar to ASPC_ECOLI gi|1787159 percent identity 99 in 396 aa (Conserved in E.coli K-12).
   
 0.963
ECs4091
Glutamate synthase large subunit; Similar to GLTB_ECOLI gi|1789605 percent identity 99 in 1517 aa (Conserved in E.coli K-12).
  
 
 0.959
ECs3325
Putative multimodular enzyme; Similar to B2463_ECOLI gi|1788806 percent identity 99 in 759 aa (Conserved in E.coli K-12).
  
 0.958
Your Current Organism:
Escherichia coli O157H7 Sakai
NCBI taxonomy Id: 386585
Other names: E. coli O157:H7 str. Sakai, Escherichia coli O157:H7 str. Sakai, Escherichia coli O157:H7 strain Sakai
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.