STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDG85254.1Long-chain acyl-CoA synthetase. (604 aa)    
Predicted Functional Partners:
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
  0.788
SDG43927.1
PAS domain S-box-containing protein.
   
 
  0.729
SDG53772.1
PAS domain S-box-containing protein.
   
 
  0.729
SDG56188.1
PAS domain S-box-containing protein.
   
 
  0.729
SDG96884.1
PAS domain S-box-containing protein.
   
 
  0.729
SDH23882.1
PAS domain S-box-containing protein.
   
 
  0.729
SDG75744.1
Ankyrin repeat.
  
 0.694
rplE
Large subunit ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
    
 
 0.668
SDH26485.1
3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
   
 0.628
hisZ
ATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
 
     0.615
Your Current Organism:
Roseospirillum parvum
NCBI taxonomy Id: 83401
Other names: DSM 12498, R. parvum, Roseospirillum parvum Glaeser and Overmann 2001, strain 930I
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.